Histocompatibility Antigens Class I
"Histocompatibility Antigens Class I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
Descriptor ID |
D015395
|
MeSH Number(s) |
D12.776.395.550.489 D12.776.543.550.439 D23.050.301.500.100 D23.050.705.552.100
|
Concept/Terms |
Histocompatibility Antigens Class I- Histocompatibility Antigens Class I
- Class I Histocompatibility Antigens
- Class I Antigens
- Antigens, Class I
- I Antigens, Class
- Class I Major Histocompatibility Antigens
|
Below are MeSH descriptors whose meaning is more general than "Histocompatibility Antigens Class I".
Below are MeSH descriptors whose meaning is more specific than "Histocompatibility Antigens Class I".
This graph shows the total number of publications written about "Histocompatibility Antigens Class I" by people in this website by year, and whether "Histocompatibility Antigens Class I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1994 | 0 | 3 | 3 |
1995 | 0 | 2 | 2 |
1996 | 3 | 0 | 3 |
1997 | 2 | 2 | 4 |
1998 | 3 | 3 | 6 |
1999 | 4 | 2 | 6 |
2000 | 1 | 4 | 5 |
2001 | 4 | 1 | 5 |
2002 | 2 | 0 | 2 |
2003 | 5 | 3 | 8 |
2004 | 2 | 3 | 5 |
2005 | 7 | 4 | 11 |
2006 | 2 | 1 | 3 |
2007 | 5 | 1 | 6 |
2008 | 3 | 2 | 5 |
2009 | 2 | 3 | 5 |
2010 | 0 | 2 | 2 |
2011 | 3 | 2 | 5 |
2012 | 1 | 4 | 5 |
2013 | 7 | 4 | 11 |
2014 | 2 | 3 | 5 |
2015 | 2 | 0 | 2 |
2016 | 4 | 2 | 6 |
2017 | 2 | 2 | 4 |
2018 | 5 | 0 | 5 |
2019 | 5 | 2 | 7 |
2020 | 1 | 1 | 2 |
2021 | 1 | 1 | 2 |
2022 | 0 | 2 | 2 |
2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histocompatibility Antigens Class I" by people in Profiles.
-
Current perspectives on mass spectrometry-based immunopeptidomics: the computational angle to tumor antigen discovery. J Immunother Cancer. 2023 10; 11(10).
-
Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities. JCI Insight. 2022 11 22; 7(22).
-
Risk of Hepatocellular Carcinoma in Patients with Various HFE Genotypes. Dig Dis Sci. 2023 01; 68(1):312-322.
-
Influence of T Cell-Mediated Immune Surveillance on Somatic Mutation Occurrences in Melanoma. Front Immunol. 2021; 12:703821.
-
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance. Nat Commun. 2021 12 06; 12(1):7041.
-
MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation. J Clin Invest. 2021 01 04; 131(1).
-
Anti-tumour immunity induces aberrant peptide presentation in melanoma. Nature. 2021 02; 590(7845):332-337.
-
Alternative splicing of MR1 regulates antigen presentation to MAIT cells. Sci Rep. 2020 09 22; 10(1):15429.
-
MHC class I and II peptide homology regulates the cellular immune response. FASEB J. 2020 06; 34(6):8082-8101.
-
Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy. Breast Cancer Res. 2019 12 11; 21(1):142.