"HLA-C Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
| Descriptor ID |
D015236
|
| MeSH Number(s) |
D12.776.395.550.489.600 D12.776.543.550.439.600 D23.050.301.500.100.600 D23.050.301.500.450.390 D23.050.705.552.100.600 D23.050.705.552.450.390
|
| Concept/Terms |
HLA-C Antigens- HLA-C Antigens
- HLA C Antigens
- HLA-C
- Antigens, HLA-C
- Antigens, HLA C
|
Below are MeSH descriptors whose meaning is more general than "HLA-C Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-C Antigens".
This graph shows the total number of publications written about "HLA-C Antigens" by people in this website by year, and whether "HLA-C Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2001 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "HLA-C Antigens" by people in Profiles.
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ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts. Proc Natl Acad Sci U S A. 2021 03 02; 118(9).
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Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application. Sci Rep. 2016 Feb 23; 6:21757.
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Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS). Blood. 2013 Sep 12; 122(11):1974-82.
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Effect of donor-recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis. Lancet Oncol. 2011 Dec; 12(13):1214-21.
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A new HLA-C allele, C*08:43, identified during a UCLA Immunogenetics Centre cell exchange. Tissue Antigens. 2011 Dec; 78(6):459-60.
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Reassessing the impact of donor HLA-C genotype on long-term liver transplant survival. Am J Transplant. 2009 Jul; 9(7):1674-8.
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HLA-A, -B, -C, and -DRB1 allele and haplotype frequencies distinguish Eastern European Americans from the general European American population. Tissue Antigens. 2009 Jan; 73(1):17-32.
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Twenty-three novel alleles increase diversity at the HLA-C locus. Tissue Antigens. 2008 Jun; 71(6):560-3.
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Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome. Mol Immunol. 2008 May; 45(9):2429-36.
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HLA-A, -B, -C, -DRB1 allele and haplotype frequencies in an African American population. Tissue Antigens. 2007 Jan; 69(1):73-85.