"HLA-D Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.
Descriptor ID |
D006681
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MeSH Number(s) |
D12.776.395.550.509.400 D12.776.543.550.440.400 D23.050.301.500.400.400 D23.050.301.500.450.400 D23.050.705.552.410.400 D23.050.705.552.450.400
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Concept/Terms |
HLA-D Antigens- HLA-D Antigens
- HLA D Antigens
- Human Class II Antigens
- HLA-D
- HLA-Dw Antigens
- Antigens, HLA-Dw
- HLA Dw Antigens
- Antigens, HLA-D
- Antigens, HLA D
- Immune Response-Associated Antigens, Human
- Class II Human Antigens
- Ia-Like Antigens, Human
- Antigens, Human Ia-Like
- Human Ia-Like Antigens
- Ia Like Antigens, Human
- Immune-Associated Antigens, Human
- Antigens, Human Immune-Associated
- Human Immune-Associated Antigens
- Immune Associated Antigens, Human
- Immune-Response Antigens, Human
- Antigens, Human Immune-Response
- Human Immune-Response Antigens
- Immune Response Antigens, Human
- Immune Response Associated Antigens, Human
- HLA-Dw
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Below are MeSH descriptors whose meaning is more general than "HLA-D Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-D Antigens".
This graph shows the total number of publications written about "HLA-D Antigens" by people in this website by year, and whether "HLA-D Antigens" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 2 | 2 |
1995 | 1 | 0 | 1 |
1999 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 2 | 2 |
2006 | 1 | 0 | 1 |
2008 | 2 | 0 | 2 |
2009 | 1 | 1 | 2 |
2011 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-D Antigens" by people in Profiles.
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Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy. Clin Pharmacol Ther. 2014 Sep; 96(3):360-369.
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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. Nat Neurosci. 2013 Jul; 16(7):848-50.
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Mismatched human leukocyte antigen class II-restricted CD8? cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation. Cancer Sci. 2011 Jul; 102(7):1281-6.
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Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population. Genes Immun. 2010 Jan; 11(1):94-7.
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In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. J Immunol. 2009 May 15; 182(10):6342-52.
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Increased HLA-DMB expression in the tumor epithelium is associated with increased CTL infiltration and improved prognosis in advanced-stage serous ovarian cancer. Clin Cancer Res. 2008 Dec 01; 14(23):7667-73.
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HLA class II alleles specify phenotypes of ketosis-prone diabetes. Diabetes Care. 2008 Jun; 31(6):1195-200.
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Small molecules that enhance the catalytic efficiency of HLA-DM. J Immunol. 2006 Apr 01; 176(7):4208-20.
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Report of meeting on the development of influenza vaccines with broad spectrum and long-lasting immune responses, World Health Organization, Geneva, Switzerland, 26-27 February 2004. Vaccine. 2005 Feb 18; 23(13):1529-33.
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Human cytomegalovirus US2 causes similar effects on both major histocompatibility complex class I and II proteins in epithelial and glial cells. J Virol. 2003 Sep; 77(17):9287-94.