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XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
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XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis. Cell Death Differ. 2002 Sep; 9(9):881-92.
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subject areas
Apoptosis
Apoptosis Regulatory Proteins
Apoptotic Protease-Activating Factor 1
bcl-2-Associated X Protein
Binding Sites
Caenorhabditis elegans Proteins
Carrier Proteins
Caspase 3
Caspase 9
Caspases
Cells, Cultured
Cysteine Endopeptidases
Enzyme Inhibitors
Eukaryotic Cells
fas Receptor
Humans
Intracellular Signaling Peptides and Proteins
Mitochondrial Proteins
Models, Biological
Multienzyme Complexes
Mutation
Proteasome Endopeptidase Complex
Proteins
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2
Signal Transduction
X-Linked Inhibitor of Apoptosis Protein