"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053148
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
|
| Concept/Terms |
Procaspase-3- Procaspase-3
- Procaspase 3
- Pro-Caspase-3
- Pro Caspase 3
|
Below are MeSH descriptors whose meaning is more general than "Caspase 3".
Below are MeSH descriptors whose meaning is more specific than "Caspase 3".
This graph shows the total number of publications written about "Caspase 3" by people in this website by year, and whether "Caspase 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 5 | 5 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 8 | 8 |
| 2005 | 0 | 12 | 12 |
| 2006 | 1 | 5 | 6 |
| 2007 | 0 | 6 | 6 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 7 | 7 |
| 2010 | 1 | 4 | 5 |
| 2011 | 1 | 3 | 4 |
| 2012 | 0 | 4 | 4 |
| 2013 | 1 | 3 | 4 |
| 2014 | 3 | 3 | 6 |
| 2015 | 1 | 8 | 9 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 2 | 3 |
| 2020 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 3" by people in Profiles.
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Mitochondria-Targeting Type-I Photodrug: Harnessing Caspase-3 Activity for Pyroptotic Oncotherapy. J Am Chem Soc. 2024 04 03; 146(13):9413-9421.
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Cellular autophagy, an unbidden effect of caspase inhibition by zVAD-fmk. FEBS J. 2022 06; 289(11):3097-3100.
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Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells. Chem Biol Interact. 2020 Nov 01; 331:109279.
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Recombinant Anti-M?llerian Hormone (rAMH) for Stalling In Vitro Granulosa Cell Replication. Reprod Sci. 2020 10; 27(10):1873-1878.
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Fetal Surgery Decreases Anesthesia-Induced Neuroapoptosis in the Mid-Gestational Fetal Ovine Brain. Fetal Diagn Ther. 2019; 46(2):111-118.
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NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway. Int J Mol Sci. 2018 May 31; 19(6).
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Changes in Oxidant Defense, Apoptosis, and Cognitive Abilities During Treatment for Childhood Leukemia. Biol Res Nurs. 2018 07; 20(4):393-402.
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Neuronal degeneration and regeneration induced by axotomy in the olfactory epithelium of Xenopus laevis. Dev Neurobiol. 2017 11; 77(11):1308-1320.
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Aleglitazar, a dual peroxisome proliferator-activated receptor-a and -? agonist, protects cardiomyocytes against the adverse effects of hyperglycaemia. Diab Vasc Dis Res. 2017 03; 14(2):152-162.
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The effect of celecoxib and its combination with imatinib on human HT-29 colorectal cancer cells: Involvement of COX-2, Caspase-3, VEGF and NF-?B genes expression. Cell Mol Biol (Noisy-le-grand). 2016 Feb 29; 62(2):68-74.