"Caspase 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 7; CASPASE 8; and CASPASE 10. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053178
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| MeSH Number(s) |
D08.811.277.656.262.500.126.350.600 D08.811.277.656.300.200.126.350.600 D12.644.360.075.405.350.600 D12.776.476.075.405.350.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caspase 6".
Below are MeSH descriptors whose meaning is more specific than "Caspase 6".
This graph shows the total number of publications written about "Caspase 6" by people in this website by year, and whether "Caspase 6" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 6" by people in Profiles.
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Characterization of Calpain and Caspase-6-Generated Glial Fibrillary Acidic Protein Breakdown Products Following Traumatic Brain Injury and Astroglial Cell Injury. Int J Mol Sci. 2022 Aug 11; 23(16).
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Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice. Neurobiol Dis. 2015 Apr; 76:24-36.
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TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivation. Mol Cell Biochem. 2013 Feb; 374(1-2):181-90.
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Peptide inhibitors: Four of a kind beats a pair. Nat Chem Biol. 2012 Jun 18; 8(7):606-7.
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Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice. Hum Mol Genet. 2012 May 01; 21(9):1954-67.
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Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6. Clin Cancer Res. 2011 Apr 01; 17(7):1796-806.
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Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML. Blood. 2010 Jan 14; 115(2):306-14.
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Desmin mediates TNF-alpha-induced aggregate formation and intercalated disk reorganization in heart failure. J Cell Biol. 2008 Jun 02; 181(5):761-75.
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Huntingtin's critical cleavage. Nat Neurosci. 2006 Sep; 9(9):1088-9.
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Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology. 2005 Jan; 146(1):22-32.