"Caspase 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 7; CASPASE 8; and CASPASE 10. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053178
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| MeSH Number(s) |
D08.811.277.656.262.500.126.350.600 D08.811.277.656.300.200.126.350.600 D12.644.360.075.405.350.600 D12.776.476.075.405.350.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caspase 6".
Below are MeSH descriptors whose meaning is more specific than "Caspase 6".
This graph shows the total number of publications written about "Caspase 6" by people in this website by year, and whether "Caspase 6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 6" by people in Profiles.
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Characterization of Calpain and Caspase-6-Generated Glial Fibrillary Acidic Protein Breakdown Products Following Traumatic Brain Injury and Astroglial Cell Injury. Int J Mol Sci. 2022 Aug 11; 23(16).
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Huntingtin's critical cleavage. Nat Neurosci. 2006 Sep; 9(9):1088-9.
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Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology. 2005 Jan; 146(1):22-32.
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Sequence-based discovery of a synthetic peptide inhibitor of caspase 6. Apoptosis. 2003 Aug; 8(4):371-6.
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Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells. Mol Cell Biol. 2001 Aug; 21(15):4856-67.
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Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death. Clin Cancer Res. 2001 May; 7(5):1474-80.
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Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis. J Cell Biol. 1997 Sep 22; 138(6):1379-94.