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CHEN, JUNJIE
One or more keywords matched the following items that are connected to CHEN, JUNJIE
Item TypeName
Academic Article Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.
Academic Article MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Concept Homeodomain Proteins
Concept Cytoskeletal Proteins
Concept Adaptor Proteins, Signal Transducing
Concept Membrane Proteins
Concept DNA-Binding Proteins
Concept Heat-Shock Proteins
Concept Insulin Receptor Substrate Proteins
Concept Fanconi Anemia Complementation Group Proteins
Concept Chromosomal Proteins, Non-Histone
Concept Carrier Proteins
Concept Cell Cycle Proteins
Concept Mitochondrial Proteins
Concept Green Fluorescent Proteins
Concept Recombinant Fusion Proteins
Concept Calcium-Binding Proteins
Concept Fungal Proteins
Concept Saccharomyces cerevisiae Proteins
Concept rho GTP-Binding Proteins
Concept Nuclear Proteins
Concept Recombinant Proteins
Concept Neoplasm Proteins
Concept CCAAT-Enhancer-Binding Proteins
Concept Nonheme Iron Proteins
Concept Microtubule Proteins
Concept Mutant Proteins
Concept Pol1 Transcription Initiation Complex Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept Apoptosis Regulatory Proteins
Concept Telomere-Binding Proteins
Concept Proto-Oncogene Proteins
Concept Cullin Proteins
Concept Nerve Tissue Proteins
Concept Tumor Suppressor Proteins
Concept RNA-Binding Proteins
Concept SMN Complex Proteins
Concept Repressor Proteins
Concept Xenopus Proteins
Concept Schizosaccharomyces pombe Proteins
Concept Ubiquitinated Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Proteins
Concept Microtubule-Associated Proteins
Academic Article Whole-genome screening identifies proteins localized to distinct nuclear bodies.
Academic Article Akt regulates TPP1 homodimerization and telomere protection.
Academic Article Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.
Academic Article Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability.
Academic Article ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.
Academic Article The HARP domain dictates the annealing helicase activity of HARP/SMARCAL1.
Academic Article Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.
Academic Article FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.
Academic Article SOSS complexes participate in the maintenance of genomic stability.
Academic Article Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis.
Academic Article miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13.
Academic Article UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold.
Academic Article X-ray-mediated reduction in basic fibroblast growth factor expression in primary rat astrocyte cultures.
Academic Article Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.
Academic Article Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint.
Academic Article Use of siRNA to study the function of MDC1 in DNA damage responses.
Academic Article Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains.
Academic Article MDC1 regulates DNA-PK autophosphorylation in response to DNA damage.
Academic Article Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
Academic Article Chfr is required for tumor suppression and Aurora A regulation.
Academic Article Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo.
Academic Article RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.
Academic Article VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation.
Academic Article DNA-damage checkpoints: location, location, location.
Academic Article Topoisomerase IIalpha controls the decatenation checkpoint.
Academic Article p30 DBC is a potential regulator of tumorigenesis.
Academic Article Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.
Academic Article A pocket on the surface of the N-terminal BRCT domain of Mcph1 is required to prevent abnormal chromosome condensation.
Academic Article Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.
Academic Article Characterization of the DOT1L network: implications of diverse roles for DOT1L.
Academic Article The 53BP1-EXPAND1 connection in chromatin structure regulation.
Academic Article Critical roles of ring finger protein RNF8 in replication stress responses.
Academic Article The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection.
Academic Article Binding of TFIID to the CYC1 TATA boxes in yeast occurs independently of upstream activating sequences.
Academic Article Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.
Academic Article Evidence that partial unwrapping of DNA from nucleosomes facilitates the binding of heat shock factor following DNA replication in yeast.
Academic Article Characterization of tumor-associated Chk2 mutations.
Academic Article Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development.
Academic Article The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity.
Academic Article Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control.
Academic Article Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX.
Academic Article UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress.
Academic Article Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
Academic Article Early events in the DNA damage response.
Academic Article The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis.
Academic Article Gemcitabine-induced activation of checkpoint signaling pathways that affect tumor cell survival.
Academic Article Human TopBP1 ensures genome integrity during normal S phase.
Academic Article Chk1 is required to maintain claspin stability.
Academic Article Signaling networks controlled by the MRN complex and MDC1 during early DNA damage responses.
Academic Article Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function.
Academic Article c-Myc interacts with TRF1/PIN2 and regulates telomere length.
Academic Article MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage.
Academic Article Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.
Academic Article Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.
Academic Article Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly.
Academic Article MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks.
Academic Article Functional interaction between Chfr and Kif22 controls genomic stability.
Academic Article MRG15 is a novel PALB2-interacting factor involved in homologous recombination.
Academic Article N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair.
Academic Article Interactions between DBC1 and SIRT 1 are deregulated in breast cancer cells.
Academic Article MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.
Academic Article BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.
Academic Article SON is a spliceosome-associated factor required for mitotic progression.
Academic Article The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments.
Academic Article RAD18 lives a double life: Its implication in DNA double-strand break repair.
Academic Article Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.
Academic Article The role of the human SWI5-MEI5 complex in homologous recombination repair.
Academic Article MDC1 collaborates with TopBP1 in DNA replication checkpoint control.
Academic Article hSWS1?SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.
Academic Article MEMO1, a new IRS1-interacting protein, induces epithelial-mesenchymal transition in mammary epithelial cells.
Academic Article PTPN14 is required for the density-dependent control of YAP1.
Academic Article The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1.
Academic Article RIF1 counteracts BRCA1-mediated end resection during DNA repair.
Academic Article FIGNL1-containing protein complex is required for efficient homologous recombination repair.
Academic Article Deubiquitylation and stabilization of PTEN by USP13.
Academic Article A distal heat shock element promotes the rapid response to heat shock of the HSP26 gene in the yeast Saccharomyces cerevisiae.
Academic Article A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo.
Academic Article Loss of transactivation and transrepression function, and not RPA binding, alters growth suppression by p53.
Academic Article Cyclin-binding motifs are essential for the function of p21CIP1.
Academic Article p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex.
Academic Article Association of BRCA1 with Rad51 in mitotic and meiotic cells.
Academic Article Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage.
Academic Article Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
Academic Article Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.
Academic Article MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways.
Academic Article Human claspin is required for replication checkpoint control.
Academic Article Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment.
Academic Article The BRCT domain is a phospho-protein binding domain.
Academic Article 53BP1 is required for class switch recombination.
Academic Article DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains.
Academic Article ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis.
Academic Article BRCA1 participates in DNA decatenation.
Academic Article Genomic instability in laminopathy-based premature aging.
Academic Article The mitotic checkpoint in cancer and aging: what have mice taught us?
Academic Article 53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice.
Academic Article MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals.
Academic Article CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage.
Academic Article Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Academic Article Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response.
Academic Article CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.
Academic Article Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.
Academic Article DBC1 is a negative regulator of SIRT1.
Academic Article Mammalian DNA damage response pathway.
Academic Article Polo-like kinase 1 is essential for early embryonic development and tumor suppression.
Academic Article When loose ends finally meet.
Academic Article Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.
Academic Article Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.
Academic Article PALB2 is an integral component of the BRCA complex required for homologous recombination repair.
Academic Article RAD18 transmits DNA damage signalling to elicit homologous recombination repair.
Academic Article PALB2 regulates recombinational repair through chromatin association and oligomerization.
Academic Article A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Academic Article Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.
Academic Article Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.
Academic Article Angiomotin-like proteins associate with and negatively regulate YAP1.
Academic Article SET nuclear oncogene associates with microcephalin/MCPH1 and regulates chromosome condensation.
Academic Article RAD18-BRCTx interaction is required for efficient repair of UV-induced DNA damage.
Academic Article The E3 ligase RNF8 regulates KU80 removal and NHEJ repair.
Academic Article Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair.
Academic Article ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
Academic Article PNUTS functions as a proto-oncogene by sequestering PTEN.
Academic Article PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis.
Academic Article Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Academic Article Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response.
Academic Article Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.
Academic Article BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway.
Academic Article DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Academic Article p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
Academic Article Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks.
Academic Article Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.
Academic Article The role of Vpr in HIV-1 disease progression is independent of its G2 arrest induction function.
Academic Article The tandem BRCT domain of 53BP1 is not required for its repair function.
Academic Article Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells.
Academic Article Differences in DNA double strand breaks repair in male germ cell types: lessons learned from a differential expression of Mdc1 and 53BP1.
Academic Article New players in the BRCA1-mediated DNA damage responsive pathway.
Academic Article Histone ubiquitination associates with BRCA1-dependent DNA damage response.
Academic Article Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression.
Academic Article CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Academic Article MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells.
Academic Article RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo.
Academic Article KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR).
Academic Article FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions.
Academic Article TopBP1 controls BLM protein level to maintain genome stability.
Academic Article Claspin, a regulator of Chk1 in DNA replication stress pathway.
Academic Article BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP.
Academic Article Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.
Academic Article TopBP1 stabilizes BLM protein to suppress sister chromatid exchange.
Academic Article BRCA proteins and DNA damage checkpoints
Academic Article Tankyrase Inhibitors Target YAP by Stabilizing Angiomotin Family Proteins
Concept Poly-ADP-Ribose Binding Proteins
Concept LIM Domain Proteins
Concept Ataxia Telangiectasia Mutated Proteins
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