Item Type | Name |
Concept
|
Viral Core Proteins
|
Concept
|
Cytoskeletal Proteins
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Proto-Oncogene Proteins c-myc
|
Concept
|
Adenovirus E4 Proteins
|
Concept
|
Membrane Proteins
|
Concept
|
Viral Regulatory and Accessory Proteins
|
Concept
|
DNA-Binding Proteins
|
Concept
|
Oncogene Proteins, Fusion
|
Concept
|
Heat-Shock Proteins
|
Concept
|
Luminescent Proteins
|
Concept
|
Chromosomal Proteins, Non-Histone
|
Concept
|
Carrier Proteins
|
Concept
|
Oncogene Proteins
|
Concept
|
Cell Cycle Proteins
|
Concept
|
Viral Structural Proteins
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
ras Proteins
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Capsid Proteins
|
Concept
|
Fungal Proteins
|
Concept
|
Saccharomyces cerevisiae Proteins
|
Concept
|
Nuclear Proteins
|
Concept
|
Recombinant Proteins
|
Concept
|
Neoplasm Proteins
|
Concept
|
CCAAT-Enhancer-Binding Proteins
|
Concept
|
Viral Matrix Proteins
|
Concept
|
Viral Fusion Proteins
|
Concept
|
Proto-Oncogene Proteins c-fos
|
Concept
|
Mutant Proteins
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Proto-Oncogene Proteins c-mdm2
|
Concept
|
Proto-Oncogene Proteins c-maf
|
Concept
|
Cyclin-Dependent Kinase Inhibitor Proteins
|
Concept
|
Proto-Oncogene Proteins
|
Concept
|
Viral Envelope Proteins
|
Concept
|
Tumor Suppressor Proteins
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Viral Proteins
|
Concept
|
Repressor Proteins
|
Concept
|
Immediate-Early Proteins
|
Concept
|
Cornified Envelope Proline-Rich Proteins
|
Concept
|
Proteins
|
Concept
|
Microtubule-Associated Proteins
|
Academic Article
|
Oncogenic capacity of the E2F1 gene.
|
Academic Article
|
E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model.
|
Academic Article
|
The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes.
|
Academic Article
|
Regulation of E2F-1 gene expression by p130 (Rb2) and D-type cyclin kinase activity.
|
Academic Article
|
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.
|
Academic Article
|
A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.
|
Academic Article
|
Role of E2F in cell cycle control and cancer.
|
Academic Article
|
Differential activities of E2F family members: unique functions in regulating transcription.
|
Academic Article
|
Conditional transformation of rat embryo fibroblast cells by a cyclin D1-cdk4 fusion gene.
|
Academic Article
|
ARF differentially modulates apoptosis induced by E2F1 and Myc.
|
Academic Article
|
Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.
|
Academic Article
|
Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues.
|
Academic Article
|
E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks.
|
Academic Article
|
Expression of transcription factor E2F1 induces quiescent cells to enter S phase.
|
Academic Article
|
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development.
|
Academic Article
|
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.
|
Academic Article
|
Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin.
|
Academic Article
|
Regulation of BRCA1 expression by the Rb-E2F pathway.
|
Academic Article
|
E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo.
|
Academic Article
|
E2F-1 gene transfer enhances invasiveness of human head and neck carcinoma cell lines.
|
Academic Article
|
Regulation of cellular invasion and matrix metalloproteinase activity in HepG2 cell by connexin 26 transfection.
|
Academic Article
|
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.
|
Academic Article
|
Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
|
Academic Article
|
ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.
|
Academic Article
|
Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.
|
Academic Article
|
A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.
|
Academic Article
|
Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif.
|
Academic Article
|
High-affinity binding of the cell cycle-regulated transcription factors E2F1 and E2F4 to benzo[a]pyrene diol epoxide-DNA adducts.
|
Academic Article
|
The paradox of E2F1: oncogene and tumor suppressor gene.
|
Academic Article
|
Molecular cloning and characterization of a novel mouse epidermal differentiation gene and its promoter.
|
Academic Article
|
The RB-E2F1 pathway regulates autophagy.
|
Academic Article
|
Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck.
|
Academic Article
|
The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro.
|
Academic Article
|
Myc lacks E2F1's ability to suppress skin carcinogenesis.
|
Academic Article
|
Human cytomegalovirus US7, US8, US9, and US10 are cytoplasmic glycoproteins, not found at cell surfaces, and US9 does not mediate cell-to-cell spread.
|
Academic Article
|
Binding of human cytomegalovirus US2 to major histocompatibility complex class I and II proteins is not sufficient for their degradation.
|
Academic Article
|
Herpes simplex virus gE/gI expressed in epithelial cells interferes with cell-to-cell spread.
|
Academic Article
|
Human cytomegalovirus US3 chimeras containing US2 cytosolic residues acquire major histocompatibility class I and II protein degradation properties.
|
Academic Article
|
Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity.
|
Academic Article
|
Herpes simplex virus glycoproteins gD and gE/gI serve essential but redundant functions during acquisition of the virion envelope in the cytoplasm.
|
Academic Article
|
Human cytomegalovirus US2 causes similar effects on both major histocompatibility complex class I and II proteins in epithelial and glial cells.
|
Academic Article
|
Redistribution of cellular and herpes simplex virus proteins from the trans-golgi network to cell junctions without enveloped capsids.
|
Academic Article
|
Herpes keratitis in the absence of anterograde transport of virus from sensory ganglia to the cornea.
|
Academic Article
|
The extracellular domain of herpes simplex virus gE is indispensable for efficient cell-to-cell spread: evidence for gE/gI receptors.
|
Academic Article
|
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL.
|
Academic Article
|
Inhibition of TCR signaling by herpes simplex virus.
|
Academic Article
|
Herpes simplex virus gE/gI must accumulate in the trans-Golgi network at early times and then redistribute to cell junctions to promote cell-cell spread.
|
Academic Article
|
The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins.
|
Academic Article
|
Herpes simplex virus capsids are transported in neuronal axons without an envelope containing the viral glycoproteins.
|
Academic Article
|
Cytoplasmic residues of herpes simplex virus glycoprotein gE required for secondary envelopment and binding of tegument proteins VP22 and UL11 to gE and gD.
|
Academic Article
|
A herpes simplex virus gD-YFP fusion glycoprotein is transported separately from viral capsids in neuronal axons.
|
Academic Article
|
Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma.
|
Academic Article
|
Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.
|
Academic Article
|
Herpes simplex virus gE/gI and US9 proteins promote transport of both capsids and virion glycoproteins in neuronal axons.
|
Academic Article
|
HCMV gH/gL/UL128-131 interferes with virus entry into epithelial cells: evidence for cell type-specific receptors.
|
Academic Article
|
Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans.
|
Academic Article
|
Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase.
|
Academic Article
|
Adenovirus vectors expressing hantavirus proteins protect hamsters against lethal challenge with andes virus.
|
Academic Article
|
Fusion between perinuclear virions and the outer nuclear membrane requires the fusogenic activity of herpes simplex virus gB.
|
Academic Article
|
A human cytomegalovirus gO-null mutant fails to incorporate gH/gL into the virion envelope and is unable to enter fibroblasts and epithelial and endothelial cells.
|
Academic Article
|
Human cytomegalovirus TR strain glycoprotein O acts as a chaperone promoting gH/gL incorporation into virions but is not present in virions.
|
Academic Article
|
XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments.
|
Academic Article
|
Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells.
|
Academic Article
|
Herpes simplex virus glycoproteins gB and gD function in a redundant fashion to promote secondary envelopment.
|
Academic Article
|
Anterograde transport of herpes simplex virus capsids in neurons by both separate and married mechanisms.
|
Academic Article
|
Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis.
|
Academic Article
|
Low-pH-dependent changes in the conformation and oligomeric state of the prefusion form of herpes simplex virus glycoprotein B are separable from fusion activity.
|
Academic Article
|
Human cytomegalovirus glycoprotein gO complexes with gH/gL, promoting interference with viral entry into human fibroblasts but not entry into epithelial cells.
|
Academic Article
|
Altered fear learning across development in both mouse and human.
|
Academic Article
|
Herpes simplex virus membrane proteins gE/gI and US9 act cooperatively to promote transport of capsids and glycoproteins from neuron cell bodies into initial axon segments.
|
Academic Article
|
HCMV gB shares structural and functional properties with gB proteins from other herpesviruses.
|
Academic Article
|
Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.
|
Academic Article
|
Human cytomegalovirus (HCMV) glycoprotein gB promotes virus entry in trans acting as the viral fusion protein rather than as a receptor-binding protein.
|
Academic Article
|
Human cytomegalovirus Fc? binding proteins gp34 and gp68 antagonize Fc? receptors I, II and III.
|
Academic Article
|
Herpes simplex virus gE/gI extracellular domains promote axonal transport and spread from neurons to epithelial cells.
|
Academic Article
|
The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells.
|
Academic Article
|
APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma.
|
Academic Article
|
Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
|
Academic Article
|
Human Cytomegalovirus gH/gL Forms a Stable Complex with the Fusion Protein gB in Virions.
|
Academic Article
|
Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.
|
Academic Article
|
Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression.
|
Academic Article
|
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci.
|
Academic Article
|
Herpes Simplex Virus gE/gI and US9 Promote both Envelopment and Sorting of Virus Particles in the Cytoplasm of Neurons, Two Processes That Precede Anterograde Transport in Axons.
|
Academic Article
|
Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism.
|
Academic Article
|
CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.
|
Academic Article
|
Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.
|
Academic Article
|
The Human Cytomegalovirus Trimer and Pentamer Promote Sequential Steps in Entry into Epithelial and Endothelial Cells at Cell Surfaces and Endosomes.
|
Academic Article
|
The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation.
|
Concept
|
Ataxia Telangiectasia Mutated Proteins
|
Academic Article
|
Characterization of the Herpes Simplex Virus (HSV) Tegument Proteins That Bind to gE/gI and US9, Which Promote Assembly of HSV and Transport into Neuronal Axons.
|
Academic Article
|
Anterograde transport of a-herpesviruses in neuronal axons.
|
Academic Article
|
Herpesvirus Nuclear Egress across the Outer Nuclear Membrane.
|
Academic Article
|
Identification of functionally important domains of human cytomegalovirus gO that act after trimer binding to receptors.
|
Academic Article
|
Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport.
|