"Deubiquitinating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that remove UBIQUITIN from a protein substrate, including POLYUBIQUITIN, or from other molecules.
| Descriptor ID |
D000072017
|
| MeSH Number(s) |
D08.811.037
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Deubiquitinating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Deubiquitinating Enzymes".
This graph shows the total number of publications written about "Deubiquitinating Enzymes" by people in this website by year, and whether "Deubiquitinating Enzymes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deubiquitinating Enzymes" by people in Profiles.
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The deubiquitinase ZRANB1 is an E3 ubiquitin ligase for SLC7A11 and regulates ferroptotic resistance. J Cell Biol. 2023 11 06; 222(11).
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A gene signature consisting of ubiquitin ligases and deubiquitinating enzymes of SKP2 is associated with clinical outcome in breast cancer. Sci Rep. 2022 02 15; 12(1):2478.
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USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer. Genes Dev. 2021 10 01; 35(19-20):1327-1332.
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Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance. Nat Commun. 2021 06 29; 12(1):4033.
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Targeting ubiquitin signaling for cancer immunotherapy. Signal Transduct Target Ther. 2021 01 13; 6(1):16.
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Elevated post-ischemic ubiquitination results from suppression of deubiquitinase activity and not proteasome inhibition. Cell Mol Life Sci. 2021 Mar; 78(5):2169-2183.
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Regulation of Histone Ubiquitination in Response to DNA Double Strand Breaks. Cells. 2020 07 16; 9(7).
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CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell models. Sci Rep. 2020 03 24; 10(1):5350.
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Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne. Genes Dev. 2019 12 01; 33(23-24):1702-1717.
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BRCA1/BRCA2-containing complex subunit 3 controls oligodendrocyte differentiation by dynamically regulating lysine 63-linked ubiquitination. Glia. 2019 09; 67(9):1775-1792.