"Deubiquitinating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that remove UBIQUITIN from a protein substrate, including POLYUBIQUITIN, or from other molecules.
| Descriptor ID |
D000072017
|
| MeSH Number(s) |
D08.811.037
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Deubiquitinating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Deubiquitinating Enzymes".
This graph shows the total number of publications written about "Deubiquitinating Enzymes" by people in this website by year, and whether "Deubiquitinating Enzymes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Deubiquitinating Enzymes" by people in Profiles.
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Elevated post-ischemic ubiquitination results from suppression of deubiquitinase activity and not proteasome inhibition. Cell Mol Life Sci. 2021 Mar; 78(5):2169-2183.
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BRCA1/BRCA2-containing complex subunit 3 controls oligodendrocyte differentiation by dynamically regulating lysine 63-linked ubiquitination. Glia. 2019 09; 67(9):1775-1792.
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Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis. ChemMedChem. 2018 10 08; 13(19):2014-2023.
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Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome. Am J Hum Genet. 2018 02 01; 102(2):296-308.
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Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. J Autoimmun. 2017 Jun; 80:65-76.
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Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol Cell. 2015 Sep 17; 59(6):970-83.
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OTUD7B controls non-canonical NF-?B activation through deubiquitination of TRAF3. Nature. 2013 Feb 21; 494(7437):371-4.
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NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes. J Biol Chem. 2011 Apr 01; 286(13):11734-45.
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The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments. J Biol Chem. 2010 Oct 01; 285(40):30982-8.
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OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity. J Biol Chem. 2009 Jun 12; 284(24):16135-16145.