"RNA, Catalytic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
| Descriptor ID |
D016337
|
| MeSH Number(s) |
D08.811.797 D13.444.735.790.199
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "RNA, Catalytic".
Below are MeSH descriptors whose meaning is more specific than "RNA, Catalytic".
This graph shows the total number of publications written about "RNA, Catalytic" by people in this website by year, and whether "RNA, Catalytic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 1 | 1 | 2 |
| 1998 | 4 | 4 | 8 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 3 | 2 | 5 |
| 2005 | 0 | 1 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "RNA, Catalytic" by people in Profiles.
-
A suppressor tRNA-mediated feedforward loop eliminates leaky gene expression in bacteria. Nucleic Acids Res. 2021 03 18; 49(5):e25.
-
Tuning RNA folding and function through rational design of junction topology. Nucleic Acids Res. 2017 09 19; 45(16):9706-9715.
-
Molecular Dynamics Study of Twister Ribozyme: Role of Mg(2+) Ions and the Hydrogen-Bonding Network in the Active Site. Biochemistry. 2016 07 12; 55(27):3834-46.
-
Non-coding RNAs: Therapeutic Strategies and Delivery Systems. Adv Exp Med Biol. 2016; 937:229-37.
-
Secondary structure encodes a cooperative tertiary folding funnel in the Azoarcus ribozyme. Nucleic Acids Res. 2016 Jan 08; 44(1):402-12.
-
An open-label, phase 2 trial of RPI.4610 (Angiozyme) in the treatment of metastatic breast cancer. Cancer. 2012 Sep 01; 118(17):4098-104.
-
Solution structure of RNase P RNA. RNA. 2011 Jun; 17(6):1159-71.
-
The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death. J Cell Biol. 2008 Nov 03; 183(3):429-39.
-
Multiple myeloma cell killing by depletion of the MET receptor tyrosine kinase. Cancer Res. 2007 Oct 15; 67(20):9913-20.
-
Engineering high-speed allosteric hammerhead ribozymes. Biol Chem. 2007 Aug; 388(8):779-86.