"RNA, Catalytic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
| Descriptor ID |
D016337
|
| MeSH Number(s) |
D08.811.797 D13.444.735.790.199
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "RNA, Catalytic".
Below are MeSH descriptors whose meaning is more specific than "RNA, Catalytic".
This graph shows the total number of publications written about "RNA, Catalytic" by people in this website by year, and whether "RNA, Catalytic" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1998 | 3 | 0 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA, Catalytic" by people in Profiles.
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A suppressor tRNA-mediated feedforward loop eliminates leaky gene expression in bacteria. Nucleic Acids Res. 2021 03 18; 49(5):e25.
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Tuning RNA folding and function through rational design of junction topology. Nucleic Acids Res. 2017 09 19; 45(16):9706-9715.
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Secondary structure encodes a cooperative tertiary folding funnel in the Azoarcus ribozyme. Nucleic Acids Res. 2016 Jan 08; 44(1):402-12.
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Engineering high-speed allosteric hammerhead ribozymes. Biol Chem. 2007 Aug; 388(8):779-86.
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Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006 May; 12(5):797-806.
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Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 2004 Sep 23; 431(7007):471-6.
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Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7392-7.
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Design, targeting, and initial screening of sTRSV-derived hairpin ribozymes for optimum helix 1 length and catalytic efficiency in vitro. Methods Mol Biol. 2004; 252:339-58.
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Reduction of functional N-methyl-D-aspartate receptors in neurons by RNase P-mediated cleavage of the NR1 mRNA. J Neurochem. 2001 Mar; 76(5):1386-94.
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Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors. Clin Cancer Res. 2000 May; 6(5):2094-103.