"Gene Fusion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.
| Descriptor ID |
D050939
|
| MeSH Number(s) |
G05.728.385
|
| Concept/Terms |
Gene Fusion- Gene Fusion
- Fusion, Gene
- Fusions, Gene
- Gene Fusions
|
Below are MeSH descriptors whose meaning is more general than "Gene Fusion".
Below are MeSH descriptors whose meaning is more specific than "Gene Fusion".
This graph shows the total number of publications written about "Gene Fusion" by people in this website by year, and whether "Gene Fusion" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2011 | 1 | 2 | 3 |
| 2013 | 0 | 3 | 3 |
| 2014 | 3 | 1 | 4 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 0 | 2 |
| 2020 | 3 | 1 | 4 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Fusion" by people in Profiles.
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Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions. Clin Cancer Res. 2025 Feb 03; 31(3):561-572.
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An optimized workflow of full-length transcriptome sequencing for accurate fusion transcript identification. RNA Biol. 2024 01; 21(1):122-131.
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BCR::ZNF711 and BCR::CYLC2 Fusions: Novel BCR Fusions Expanding the Molecular Spectrum of Gene Fusions in Melanoma. Am J Dermatopathol. 2024 Nov 01; 46(11):797-799.
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TPPP-BRD9 fusion-related gallbladder carcinomas are frequently associated with intracholecystic neoplasia, neuroendocrine carcinoma, and a distinctive small tubular-type adenocarcinoma commonly accompanied with a syringomatous pattern. Hum Pathol. 2024 08; 150:67-73.
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Spitz Melanoma With SLC20A1::ALK Fusion: A Novel Fusion Previously Undescribed in Spitz Melanocytic Neoplasm. Am J Dermatopathol. 2024 Oct 01; 46(10):700-703.
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RNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison. Arch Pathol Lab Med. 2024 May 01; 148(5):538-544.
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Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types. Clin Cancer Res. 2024 02 16; 30(4):836-848.
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Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas. Cancer. 2023 12 01; 129(23):3772-3782.
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Detection of clinically actionable gene fusions by next-generation sequencing-based RNA sequencing of non-small cell lung cancer cytology specimens: A single-center experience with comparison to fluorescence in?situ hybridization. Cancer Cytopathol. 2024 Jan; 132(1):41-49.
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Secretory Carcinoma with ETV6-NTRK3 Gene Fusion and Lymph Node Metastasis in Maxillary Gingiva: A Case Report with Pathological and Molecular Correlative Studies. Ann Clin Lab Sci. 2023 Sep; 53(5):800-805.