"Gene Fusion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.
Descriptor ID |
D050939
|
MeSH Number(s) |
G05.728.385
|
Concept/Terms |
Gene Fusion- Gene Fusion
- Fusion, Gene
- Fusions, Gene
- Gene Fusions
|
Below are MeSH descriptors whose meaning is more general than "Gene Fusion".
Below are MeSH descriptors whose meaning is more specific than "Gene Fusion".
This graph shows the total number of publications written about "Gene Fusion" by people in this website by year, and whether "Gene Fusion" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2006 | 0 | 2 | 2 |
2007 | 0 | 1 | 1 |
2008 | 0 | 2 | 2 |
2009 | 1 | 1 | 2 |
2010 | 3 | 3 | 6 |
2011 | 5 | 5 | 10 |
2012 | 0 | 1 | 1 |
2013 | 1 | 6 | 7 |
2014 | 3 | 3 | 6 |
2015 | 2 | 4 | 6 |
2016 | 4 | 0 | 4 |
2017 | 2 | 5 | 7 |
2018 | 5 | 1 | 6 |
2019 | 2 | 0 | 2 |
2020 | 5 | 3 | 8 |
2021 | 6 | 2 | 8 |
2022 | 0 | 9 | 9 |
2023 | 0 | 6 | 6 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Fusion" by people in Profiles.
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Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types. Clin Cancer Res. 2024 02 16; 30(4):836-848.
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Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas. Cancer. 2023 12 01; 129(23):3772-3782.
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Detection of clinically actionable gene fusions by next-generation sequencing-based RNA sequencing of non-small cell lung cancer cytology specimens: A single-center experience with comparison to fluorescence in?situ hybridization. Cancer Cytopathol. 2024 Jan; 132(1):41-49.
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Secretory Carcinoma with ETV6-NTRK3 Gene Fusion and Lymph Node Metastasis in Maxillary Gingiva: A Case Report with Pathological and Molecular Correlative Studies. Ann Clin Lab Sci. 2023 Sep; 53(5):800-805.
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Diagnosis and Management of Tropomyosin Receptor Kinase Fusion-Positive Thyroid Carcinomas: A Review. JAMA Oncol. 2023 08 01; 9(8):1132-1141.
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A Molecular Blueprint to Targeting ALK Gene Fusions in Glioblastoma. Clin Cancer Res. 2023 07 14; 29(14):2567-2569.
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Sarcoma with MGA::NUTM1 fusion: a report of three cases and literature review. Histopathology. 2023 Nov; 83(5):712-721.
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Complete mimicry: Rhabdomyosarcoma with FUS::TFCP2 fusion masquerading as carcinoma-diagnostic challenge and report of two cases. Genes Chromosomes Cancer. 2023 07; 62(7):430-436.
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Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia. Nat Commun. 2022 09 14; 13(1):5401.
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Pan-cancer efficacy of pralsetinib in patients with RET fusion-positive solid tumors from the phase 1/2 ARROW trial. Nat Med. 2022 08; 28(8):1640-1645.