"V(D)J Recombination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which the V (variable), D (diversity), and J (joining) segments of IMMUNOGLOBULIN GENES or T-CELL RECEPTOR GENES are assembled during the development of LYMPHOID CELLS using NONHOMOLOGOUS DNA END-JOINING.
| Descriptor ID |
D060152
|
| MeSH Number(s) |
G05.344.900 G05.728.932
|
| Concept/Terms |
V(D)J Recombination- V(D)J Recombination
- VDJ Recombination
- Recombination, VDJ
- Recombinations, VDJ
- VDJ Recombinations
|
Below are MeSH descriptors whose meaning is more general than "V(D)J Recombination".
Below are MeSH descriptors whose meaning is more specific than "V(D)J Recombination".
This graph shows the total number of publications written about "V(D)J Recombination" by people in this website by year, and whether "V(D)J Recombination" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "V(D)J Recombination" by people in Profiles.
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The fundamental role of chromatin loop extrusion in physiological V(D)J recombination. Nature. 2019 09; 573(7775):600-604.
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Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenstr?m macroglobulinemia. Blood. 2016 08 11; 128(6):827-38.
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Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPa. Leukemia. 2016 Mar; 30(3):674-82.
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Tissue-specific expressed antibody variable gene repertoires. PLoS One. 2014; 9(6):e100839.
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Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire. Immunology. 2012 Sep; 137(1):56-64.
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High-throughput antibody sequencing reveals genetic evidence of global regulation of the na?ve and memory repertoires that extends across individuals. Genes Immun. 2012 Sep; 13(6):469-73.
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Genotoxicity associated with hydroxyurea exposure in infants with sickle cell anemia: results from the BABY-HUG Phase III Clinical Trial. Pediatr Blood Cancer. 2012 Aug; 59(2):254-7.
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Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a study of seven cases. Mod Pathol. 2011 Nov; 24(11):1421-32.