"Holoenzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalytically active enzymes that are formed by the combination of an apoenzyme (APOENZYMES) and its appropriate cofactors and prosthetic groups.
| Descriptor ID |
D020035
|
| MeSH Number(s) |
D08.811.255
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Holoenzymes".
Below are MeSH descriptors whose meaning is more specific than "Holoenzymes".
This graph shows the total number of publications written about "Holoenzymes" by people in this website by year, and whether "Holoenzymes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Holoenzymes" by people in Profiles.
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Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM. Prog Biophys Mol Biol. 2021 08; 163:74-86.
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Real-time observation of polymerase-promoter contact remodeling during transcription initiation. Nat Commun. 2017 10 27; 8(1):1178.
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The DNA polymerase III holoenzyme contains ? and is not a trimeric polymerase. Nucleic Acids Res. 2016 Feb 18; 44(3):1285-97.
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AMPK: a contextual oncogene or tumor suppressor? Cancer Res. 2013 May 15; 73(10):2929-35.
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Super DksAs: substitutions in DksA enhancing its effects on transcription initiation. EMBO J. 2009 Jun 17; 28(12):1720-31.
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PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell. 2007 Sep 21; 130(6):1032-43.
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Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects syndrome. Am J Hum Genet. 2006 Nov; 79(5):878-89.
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Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome. Hum Mol Genet. 2002 Dec 01; 11(25):3237-48.
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An activator binding module of yeast RNA polymerase II holoenzyme. Mol Cell Biol. 1999 Apr; 19(4):2967-76.
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Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Mol Cell Biol. 1999 Feb; 19(2):979-88.