"Proto-Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
| Descriptor ID |
D011519
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogenes".
- Proto-Oncogenes
- Genes, abl
- Genes, bcl-1
- Genes, bcl-2
- Genes, erbA
- Genes, erbB
- Genes, fms
- Genes, fos
- Genes, jun
- Genes, mos
- Genes, myb
- Genes, myc
- Genes, ras
- Genes, rel
- Genes, sis
- Genes, src
This graph shows the total number of publications written about "Proto-Oncogenes" by people in this website by year, and whether "Proto-Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 1 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogenes" by people in Profiles.
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Comparative genomic expression signatures of signal transduction pathways and targets in paediatric Burkitt lymphoma: a Children's Oncology Group report. Br J Haematol. 2017 05; 177(4):601-611.
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High-Fat Diet-Induced Complement Activation Mediates Intestinal Inflammation and Neoplasia, Independent of Obesity. Mol Cancer Res. 2016 10; 14(10):953-965.
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PNUTS functions as a proto-oncogene by sequestering PTEN. Cancer Res. 2013 Jan 01; 73(1):205-14.
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Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal. 2010 Apr 13; 3(117):ra29.
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Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 2008 Oct 23; 455(7216):1069-75.
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BCR-ABL fusion transcript types and levels and their interaction with secondary genetic changes in determining the phenotype of Philadelphia chromosome-positive leukemias. Blood. 2008 Dec 15; 112(13):5190-2.
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Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. Nat Immunol. 2007 Oct; 8(10):1132-9.
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Aberrant EVI1 expression in acute myeloid leukemias associated with the t(3;8)(q26;q24). Cancer Genet Cytogenet. 2007 Aug; 177(1):37-42.
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Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer. Cancer Res. 2007 Apr 01; 67(7):3074-84.
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Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. PLoS Med. 2006 Dec; 3(12):e516.