"Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
| Descriptor ID |
D009857
|
| MeSH Number(s) |
G05.360.340.024.340.375.500
|
| Concept/Terms |
Oncogenes- Oncogenes
- Transforming Genes
- Transforming Gene
- Gene, Transforming
- Genes, Transforming
- Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Oncogenes".
This graph shows the total number of publications written about "Oncogenes" by people in this website by year, and whether "Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 6 | 5 | 11 |
| 1995 | 4 | 4 | 8 |
| 1996 | 4 | 3 | 7 |
| 1997 | 4 | 2 | 6 |
| 1998 | 2 | 5 | 7 |
| 1999 | 4 | 6 | 10 |
| 2000 | 3 | 7 | 10 |
| 2001 | 3 | 8 | 11 |
| 2002 | 2 | 2 | 4 |
| 2003 | 1 | 3 | 4 |
| 2004 | 2 | 5 | 7 |
| 2005 | 2 | 5 | 7 |
| 2006 | 5 | 5 | 10 |
| 2007 | 6 | 4 | 10 |
| 2008 | 6 | 7 | 13 |
| 2009 | 4 | 5 | 9 |
| 2010 | 6 | 2 | 8 |
| 2011 | 6 | 11 | 17 |
| 2012 | 4 | 9 | 13 |
| 2013 | 4 | 11 | 15 |
| 2014 | 5 | 5 | 10 |
| 2015 | 2 | 3 | 5 |
| 2016 | 9 | 6 | 15 |
| 2017 | 2 | 5 | 7 |
| 2018 | 5 | 21 | 26 |
| 2019 | 6 | 5 | 11 |
| 2020 | 6 | 13 | 19 |
| 2021 | 2 | 22 | 24 |
| 2022 | 2 | 13 | 15 |
| 2023 | 0 | 7 | 7 |
| 2024 | 1 | 3 | 4 |
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Below are the most recent publications written about "Oncogenes" by people in Profiles.
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A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity. Proc Natl Acad Sci U S A. 2024 Oct; 121(40):e2406837121.
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Somatic Mutations in Normal Tissues: Calm before the Storm. Cancer Discov. 2024 Apr 04; 14(4):605-609.
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MUC20 regulated by extrachromosomal circular DNA attenuates proteasome inhibitor resistance of multiple myeloma by modulating cuproptosis. J Exp Clin Cancer Res. 2024 Mar 05; 43(1):68.
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Advances in Immunocompetent Mouse and Rat Models. Cold Spring Harb Perspect Med. 2024 03 01; 14(3).
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Emerging therapeutics and evolving assessment criteria for intracranial metastases in patients with oncogene-driven non-small-cell lung cancer. Nat Rev Clin Oncol. 2023 10; 20(10):716-732.
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Pan-cancer proteogenomics connects oncogenic drivers to functional states. Cell. 2023 08 31; 186(18):3921-3944.e25.
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Molecular Pathways and Mechanisms of HER2 in Cancer Therapy. Clin Cancer Res. 2023 07 05; 29(13):2351-2361.
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Practices and Views of US Oncologists and Genetic Counselors Regarding Patient Recontact After Variant Reclassification: Results of a Nationwide Survey. JCO Precis Oncol. 2023 06; 7:e2300079.
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Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma. Cancer Discov. 2023 05 04; 13(5):1144-1163.
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Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment. Mol Cancer Res. 2023 05 01; 21(5):389-396.