"Genes, rel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
| Descriptor ID |
D020573
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.552
|
| Concept/Terms |
c-rel Genes- c-rel Genes
- Gene, c-rel
- Genes, c-rel
- c rel Genes
- c-rel Gene
- c-rel Proto-Oncogenes
- Proto-Oncogene, c-rel
- Proto-Oncogenes, c-rel
- c rel Proto Oncogenes
- c-rel Proto-Oncogene
v-rel Genes- v-rel Genes
- Gene, v-rel
- Genes, v-rel
- v rel Genes
- v-rel Gene
- v-rel Oncogenes
- Oncogene, v-rel
- Oncogenes, v-rel
- v rel Oncogenes
- v-rel Oncogene
- rel Oncogene
- Oncogene, rel
- Oncogenes, rel
- rel Oncogenes
|
Below are MeSH descriptors whose meaning is more general than "Genes, rel".
Below are MeSH descriptors whose meaning is more specific than "Genes, rel".
This graph shows the total number of publications written about "Genes, rel" by people in this website by year, and whether "Genes, rel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, rel" by people in Profiles.
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A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy. Oncotarget. 2014 Dec 30; 5(24):12675-93.
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REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet. 2009 Jul; 41(7):820-3.
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BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells. Blood. 2009 May 07; 113(19):4627-36.
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Nuclear CD40 interacts with c-Rel and enhances proliferation in aggressive B-cell lymphoma. Blood. 2007 Sep 15; 110(6):2121-7.
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The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation. Oncogene. 2007 Apr 05; 26(16):2318-29.
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Evolutionary relationships among Rel domains indicate functional diversification by recombination. Proc Natl Acad Sci U S A. 2001 May 08; 98(10):5740-5.