"Genes, myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
| Descriptor ID |
D016259
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.420
|
| Concept/Terms |
c-myc Genes- c-myc Genes
- Gene, c-myc
- Genes, c-myc
- c myc Genes
- c-myc Gene
c-myc Proto-Oncogenes- c-myc Proto-Oncogenes
- Proto-Oncogene, c-myc
- Proto-Oncogenes, c-myc
- c myc Proto Oncogenes
- c-myc Proto-Oncogene
v-myc Genes- v-myc Genes
- Gene, v-myc
- Genes, v-myc
- v myc Genes
- v-myc Gene
L-myc Proto-Oncogenes- L-myc Proto-Oncogenes
- L myc Proto Oncogenes
- L-myc Proto-Oncogene
- Proto-Oncogene, L-myc
- Proto-Oncogenes, L-myc
myc Oncogene- myc Oncogene
- Oncogene, myc
- Oncogenes, myc
- myc Oncogenes
N-myc Genes- N-myc Genes
- Gene, N-myc
- Genes, N-myc
- N myc Genes
- N-myc Gene
N-myc Proto-Oncogenes- N-myc Proto-Oncogenes
- N myc Proto Oncogenes
- N-myc Proto-Oncogene
- Proto-Oncogene, N-myc
- Proto-Oncogenes, N-myc
v-myc Oncogenes- v-myc Oncogenes
- Oncogene, v-myc
- Oncogenes, v-myc
- v myc Oncogenes
- v-myc Oncogene
L-myc Genes- L-myc Genes
- Gene, L-myc
- Genes, L-myc
- L myc Genes
- L-myc Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, myc".
Below are MeSH descriptors whose meaning is more specific than "Genes, myc".
This graph shows the total number of publications written about "Genes, myc" by people in this website by year, and whether "Genes, myc" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 11 | 6 | 17 |
| 1996 | 3 | 5 | 8 |
| 1997 | 4 | 2 | 6 |
| 1998 | 1 | 2 | 3 |
| 1999 | 2 | 2 | 4 |
| 2000 | 8 | 3 | 11 |
| 2001 | 1 | 3 | 4 |
| 2002 | 4 | 4 | 8 |
| 2003 | 2 | 5 | 7 |
| 2004 | 2 | 6 | 8 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 3 | 5 |
| 2007 | 2 | 1 | 3 |
| 2008 | 5 | 3 | 8 |
| 2009 | 3 | 2 | 5 |
| 2010 | 2 | 4 | 6 |
| 2011 | 6 | 3 | 9 |
| 2012 | 2 | 6 | 8 |
| 2013 | 1 | 1 | 2 |
| 2014 | 4 | 5 | 9 |
| 2015 | 6 | 1 | 7 |
| 2016 | 2 | 4 | 6 |
| 2017 | 6 | 2 | 8 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 3 | 4 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Genes, myc" by people in Profiles.
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Prognostic stratification in DLBCL patients with aberrant MYC gene. Br J Haematol. 2024 Nov; 205(5):1782-1793.
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Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 (HDAC3) Stabilization and Chromatin Condensation. Cancer Res Commun. 2022 12; 2(12):1693-1710.
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Ferroptosis vulnerability in MYCN-driven neuroblastomas. Clin Transl Med. 2022 08; 12(8):e963.
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Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer. Nature. 2022 01; 601(7893):434-439.
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EBV+ high-grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study. Histopathology. 2022 Feb; 80(3):575-588.
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Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer. Mol Cell. 2021 08 05; 81(15):3048-3064.e9.
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The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes. Sci Rep. 2020 08 18; 10(1):13942.
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Vitamin D Suppresses Ovarian Cancer Growth and Invasion by Targeting Long Non-Coding RNA CCAT2. Int J Mol Sci. 2020 Mar 27; 21(7).
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A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nat Commun. 2020 02 06; 11(1):740.
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MYC rearrangement and MYC/BCL2 double expression but not cell-of-origin predict prognosis in R-CHOP?treated diffuse large B-cell lymphoma. Eur J Haematol. 2020 Apr; 104(4):336-343.