Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).

Descriptor ID	D020570
MeSH Number(s)	G05.360.340.024.340.375.500.791.418
Concept/Terms	Genes, myb Genes, myb Gene, myb myb Gene myb Genes v-myb Genes v-myb Genes Gene, v-myb Genes, v-myb v myb Genes v-myb Gene myb Oncogene Oncogene, myb Oncogenes, myb myb Oncogenes v-myb Oncogenes Oncogene, v-myb Oncogenes, v-myb v myb Oncogenes v-myb Oncogene c-myb Genes c-myb Genes Gene, c-myb Genes, c-myb c myb Genes c-myb Gene c-myb Proto-Oncogenes Proto-Oncogene, c-myb Proto-Oncogenes, c-myb c myb Proto Oncogenes c-myb Proto-Oncogene

Below are MeSH descriptors whose meaning is more general than "Genes, myb".

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Below are MeSH descriptors whose meaning is more specific than "Genes, myb".