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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81.
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PubMed
subject areas
Adenosine
Animals
Apoptosis
Cell Cycle Checkpoints
Cell Differentiation
Cell Line, Tumor
Cell Proliferation
DNA (Cytosine-5-)-Methyltransferases
Gene Expression Regulation, Leukemic
Hematopoietic Stem Cells
Histone-Lysine N-Methyltransferase
Histones
Humans
Leukemia, Myeloid, Acute
Lysine
Methylation
Methyltransferases
Mice, Inbred C57BL
Molecular Targeted Therapy
Mutation
Phenylurea Compounds
Rats
Time Factors
Tumor Stem Cell Assay
Xenograft Model Antitumor Assays
authors with profiles
RACHEL RAU
YONGCHENG SONG
MARGARET GOODELL
MIRA JEONG
MICHAEL ANDREEFF
STEVEN M KORNBLAU