"Lysine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential amino acid. It is often added to animal feed.
| Descriptor ID |
D008239
|
| MeSH Number(s) |
D12.125.068.555 D12.125.095.647 D12.125.142.497
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lysine".
Below are MeSH descriptors whose meaning is more specific than "Lysine".
This graph shows the total number of publications written about "Lysine" by people in this website by year, and whether "Lysine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 0 | 2 | 2 |
| 1996 | 1 | 2 | 3 |
| 1997 | 1 | 3 | 4 |
| 1998 | 2 | 3 | 5 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 3 | 4 |
| 2002 | 2 | 5 | 7 |
| 2003 | 2 | 3 | 5 |
| 2004 | 3 | 3 | 6 |
| 2005 | 2 | 6 | 8 |
| 2006 | 9 | 12 | 21 |
| 2007 | 7 | 4 | 11 |
| 2008 | 3 | 5 | 8 |
| 2009 | 7 | 7 | 14 |
| 2010 | 7 | 5 | 12 |
| 2011 | 7 | 4 | 11 |
| 2012 | 5 | 6 | 11 |
| 2013 | 6 | 11 | 17 |
| 2014 | 7 | 5 | 12 |
| 2015 | 5 | 7 | 12 |
| 2016 | 3 | 9 | 12 |
| 2017 | 5 | 8 | 13 |
| 2018 | 3 | 5 | 8 |
| 2019 | 2 | 4 | 6 |
| 2020 | 3 | 8 | 11 |
| 2021 | 1 | 5 | 6 |
| 2022 | 6 | 7 | 13 |
| 2023 | 1 | 5 | 6 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Lysine" by people in Profiles.
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KAT tales: Functions of Gcn5 and PCAF lysine acetyltransferases in SAGA and ATAC. J Biol Chem. 2024 Oct; 300(10):107744.
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer. Nature. 2024 Aug; 632(8025):656-663.
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Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J Med Chem. 2024 May 23; 67(10):8186-8200.
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Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. Am J Hum Genet. 2023 11 02; 110(11):1919-1937.
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Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer. Autophagy. 2024 01; 20(1):114-130.
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Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. Neuro Oncol. 2023 07 06; 25(7):1249-1261.
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Rescue of glutaric aciduria type I in mice by liver-directed therapies. Sci Transl Med. 2023 04 19; 15(692):eadf4086.
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Sumoylation regulates functional properties of the oocyte transcription factors SOHLH1 and NOBOX. FASEB J. 2023 02; 37(2):e22747.
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Computational Investigation of a Series of Small Molecules as Potential Compounds for Lysyl Hydroxylase-2 (LH2) Inhibition. J Chem Inf Model. 2023 02 13; 63(3):986-1001.
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A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2. J Biol Chem. 2023 02; 299(2):102862.