"Prion Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
| Descriptor ID |
D000072002
|
| MeSH Number(s) |
D12.776.395.550.448.600 D12.776.543.484.500.625 D12.776.543.550.418.600 D12.776.785.340
|
| Concept/Terms |
Prion Proteins- Prion Proteins
- Prion Protein
- CD230 Antigen
- Antigen, CD230
- PrP Proteins
- Fatal Familial Insomnia Protein
- Major Prion Protein
- Prion Protein, Major
- Creutzfeldt-Jakob Disease Protein
- Creutzfeldt Jakob Disease Protein
|
Below are MeSH descriptors whose meaning is more general than "Prion Proteins".
Below are MeSH descriptors whose meaning is more specific than "Prion Proteins".
This graph shows the total number of publications written about "Prion Proteins" by people in this website by year, and whether "Prion Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Prion Proteins" by people in Profiles.
-
Effects of the pathological E200K mutation on human prion protein: A computational screening and molecular dynamics approach. J Cell Biochem. 2023 02; 124(2):254-265.
-
The vascular endothelial cell-expressed prion protein doppel promotes angiogenesis and blood-brain barrier development. Development. 2020 09 23; 147(18).
-
Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70). J Biol Chem. 2019 09 13; 294(37):13619-13628.
-
Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy. J Alzheimers Dis. 2017; 55(1):249-258.