Frontotemporal Lobar Degeneration
"Frontotemporal Lobar Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
Descriptor ID |
D057174
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MeSH Number(s) |
C10.228.140.380.266 C10.574.950.300 C18.452.845.800.300 F03.615.400.380
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Concept/Terms |
Frontotemporal Lobar Degeneration- Frontotemporal Lobar Degeneration
- Degeneration, Frontotemporal Lobar
- Degenerations, Frontotemporal Lobar
- Frontotemporal Lobar Degenerations
- Lobar Degeneration, Frontotemporal
- Lobar Degenerations, Frontotemporal
- FTLD
- FTLDs
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Below are MeSH descriptors whose meaning is more general than "Frontotemporal Lobar Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Frontotemporal Lobar Degeneration".
This graph shows the total number of publications written about "Frontotemporal Lobar Degeneration" by people in this website by year, and whether "Frontotemporal Lobar Degeneration" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frontotemporal Lobar Degeneration" by people in Profiles.
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Data stewardship in FTLD research: Investigator and research participant views. Alzheimers Dement. 2024 04; 20(4):2886-2893.
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Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia. Neurology. 2022 Aug 01; 99(5):e488-e499.
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A novel SNCA E83Q mutation in a case of dementia with Lewy bodies and atypical frontotemporal lobar degeneration. Neuropathology. 2020 Dec; 40(6):620-626.
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Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. Acta Neuropathol. 2020 02; 139(2):407-410.
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Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain. 2019 06 01; 142(6):1503-1527.
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Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. Acta Neuropathol Commun. 2018 07 04; 6(1):55.
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TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease. Acta Neuropathol Commun. 2018 05 01; 6(1):33.
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Genetics of FTLD: overview and what else we can expect from genetic studies. J Neurochem. 2016 08; 138 Suppl 1:32-53.
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Inside out: the role of nucleocytoplasmic transport in ALS and FTLD. Acta Neuropathol. 2016 08; 132(2):159-173.
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Author Response. Neurology. 2015 Oct 13; 85(15):1355.