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JIN XU

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neuroscience
Address1250 MOURSUND STREET
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pan H, Huang M, Zhu C, Lin S, He L, Shen R, Chen Y, Fang F, Qiu Y, Qin M, Bao P, Tan Y, Xu J, Ding J, Chen S. A novel compound alleviates oxidative stress via PKA/CREB1-mediated DJ-1 upregulation. J Neurochem. 2024 09; 168(9):3034-3049. PMID: 38994800.
      Citations:    
    2. Li G, Huang P, Cui S, He Y, Jiang Q, Li B, Li Y, Xu J, Wang Z, Tan Y, Chen S. Tai Chi improves non-motor symptoms of Parkinson's disease: One-year randomized controlled study with the investigation of mechanisms. Parkinsonism Relat Disord. 2024 Mar; 120:105978. PMID: 38244460.
      Citations:    
    3. Li G, Huang P, Cui SS, Tan YY, He YC, Shen X, Jiang QY, Huang P, He GY, Li BY, Li YX, Xu J, Wang Z, Chen SD. Mechanisms of motor symptom improvement by long-term Tai Chi training in Parkinson's disease patients. Transl Neurodegener. 2022 02 07; 11(1):6. PMID: 35125106; PMCID: PMC8819852.
      Citations:    
    4. Wang R, Zhang H, Du J, Xu J. Heat resilience in embryonic zebrafish revealed using an in vivo stress granule reporter. J Cell Sci. 2019 10 18; 132(20). PMID: 31558681; PMCID: PMC6826007.
      Citations:    
    5. Xu W, Bao P, Jiang X, Wang H, Qin M, Wang R, Wang T, Yang Y, Lorenzini I, Liao L, Sattler R, Xu J. Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity. Brain. 2019 05 01; 142(5):1349-1364. PMID: 30938419; PMCID: PMC6487333.
      Citations:    
    6. Wang R, Jiang X, Bao P, Qin M, Xu J. Circadian control of stress granules by oscillating EIF2a. Cell Death Dis. 2019 03 04; 10(3):215. PMID: 30833545; PMCID: PMC6399301.
      Citations:    
    7. Su J, Huang P, Qin M, Lu Q, Sang X, Cai Y, Wang Y, Liu F, Wu R, Wang X, Jiang X, Wang J, Sun Q, Chen S, Xu J. Reduction of HIP2 expression causes motor function impairment and increased vulnerability to dopaminergic degeneration in Parkinson's disease models. Cell Death Dis. 2018 10 03; 9(10):1020. PMID: 30282965; PMCID: PMC6170399.
      Citations:    
    8. Zhang T, Jiang X, Xu M, Wang H, Sang X, Qin M, Bao P, Wang R, Zhang C, Lu H, Li Y, Ren J, Chang HC, Yan J, Sun Q, Xu J. Sleep and circadian abnormalities precede cognitive deficits in R521C FUS knockin rats. Neurobiol Aging. 2018 12; 72:159-170. PMID: 30273830.
      Citations:    
    9. Xu W, Xu J. C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons. J Neurosci. 2018 08 29; 38(35):7741-7752. PMID: 30037833; PMCID: PMC6705968.
      Citations:    
    10. Yang Y, Qin M, Bao P, Xu W, Xu J. Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of a-synuclein via exosome. PLoS One. 2017; 12(7):e0180892. PMID: 28700687; PMCID: PMC5507457.
      Citations:    
    11. Wang T, Xu W, Qin M, Yang Y, Bao P, Shen F, Zhang Z, Xu J. Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response. J Biol Chem. 2016 Jul 01; 291(27):14373-14384. PMID: 27226613; PMCID: PMC4933190.
      Citations:    
    12. Wang T, Jiang X, Chen G, Xu J. Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways. Neurobiol Aging. 2015 Jan; 36(1):527-35. PMID: 25192599.
      Citations:    
    13. Shtifman A, Zhong N, Lopez JR, Shen J, Xu J. Altered Ca2+ homeostasis in the skeletal muscle of DJ-1 null mice. Neurobiol Aging. 2011 Jan; 32(1):125-32. PMID: 19683835; PMCID: PMC2888942.
      Citations:    
    14. Zhong N, Xu J. Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation. Hum Mol Genet. 2008 Nov 01; 17(21):3357-67. PMID: 18689799.
      Citations:    
    15. Zhong N, Kim CY, Rizzu P, Geula C, Porter DR, Pothos EN, Squitieri F, Heutink P, Xu J. DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor. J Biol Chem. 2006 Jul 28; 281(30):20940-20948. PMID: 16731528.
      Citations:    
    16. Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum Mol Genet. 2005 May 01; 14(9):1231-41. PMID: 15790595.
      Citations:    
    17. Shan B, Xu J, Zhuo Y, Morris CA, Morris GF. Induction of p53-dependent activation of the human proliferating cell nuclear antigen gene in chromatin by ionizing radiation. J Biol Chem. 2003 Nov 07; 278(45):44009-17. PMID: 12947108.
      Citations:    
    18. Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat Med. 2002 Jun; 8(6):600-6. PMID: 12042811.
      Citations: 281     Fields:    Translation:HumansCells
    19. Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 2000 Jan 06; 403(6765):98-103. PMID: 10638761.
      Citations: 1029     Fields:    Translation:HumansAnimalsCells
    20. Xu J, Morris GF. p53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation. Mol Cell Biol. 1999 Jan; 19(1):12-20. PMID: 9858527; PMCID: PMC83861.
      Citations: 25     Fields:    Translation:AnimalsCells
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