"Lewy Body Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Descriptor ID |
D020961
|
| MeSH Number(s) |
C10.228.140.079.862.400 C10.228.140.380.422 C10.228.662.600.200 C10.574.531 F03.615.400.512
|
| Concept/Terms |
Lewy Body Disease- Lewy Body Disease
- Diffuse Lewy Body Disease
- Lewy Body Dementia
- Cortical Lewy Body Disease
- Lewy Body Disease, Cortical
- Lewy Body Type Senile Dementia
- Lewy Body Disease, Diffuse
- Dementia, Lewy Body
|
Below are MeSH descriptors whose meaning is more general than "Lewy Body Disease".
Below are MeSH descriptors whose meaning is more specific than "Lewy Body Disease".
This graph shows the total number of publications written about "Lewy Body Disease" by people in this website by year, and whether "Lewy Body Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lewy Body Disease" by people in Profiles.
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Dementia in Severe Schizophrenia. JAMA Psychiatry. 2026 Jun 01; 83(6):590-600.
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Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation. ACS Chem Neurosci. 2023 11 01; 14(21):3913-3927.
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Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson's disease-associated GBA gene. Commun Biol. 2022 07 06; 5(1):670.
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Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain. 2020 01 01; 143(1):234-248.
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Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders. Sci Rep. 2019 07 29; 9(1):10919.
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Quantitative electroencephalography as a marker of cognitive fluctuations in dementia with Lewy bodies and an aid to differential diagnosis. Clin Neurophysiol. 2018 06; 129(6):1209-1220.
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The Role of TMEM230 Gene in Parkinson's Disease. J Parkinsons Dis. 2018; 8(4):469-477.
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An open-label study to assess safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect in dementia: PRISM II results. CNS Spectr. 2016 12; 21(6):450-459.
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Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies. Biol Psychiatry. 2015 Nov 15; 78(10):672-83.
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The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathol Commun. 2014 May 29; 2:56.