"Multiple System Atrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
| Descriptor ID |
D019578
|
| MeSH Number(s) |
C10.177.575.550 C10.228.140.079.612 C10.228.662.550 C10.574.625
|
| Concept/Terms |
Multiple System Atrophy- Multiple System Atrophy
- Atrophy, Multiple System
- Multiple System Atrophies
- Multisystem Atrophy
- Atrophies, Multisystem
- Atrophy, Multisystem
- Multisystem Atrophies
- Multisystemic Atrophy
- Atrophies, Multisystemic
- Atrophy, Multisystemic
- Multisystemic Atrophies
- Multiple System Atrophy Syndrome
|
Below are MeSH descriptors whose meaning is more general than "Multiple System Atrophy".
Below are MeSH descriptors whose meaning is more specific than "Multiple System Atrophy".
This graph shows the total number of publications written about "Multiple System Atrophy" by people in this website by year, and whether "Multiple System Atrophy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Multiple System Atrophy" by people in Profiles.
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Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum. 2024 Feb; 23(1):31-51.
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Biallelic Intronic AAGGG Expansion of RFC1 is Related to Multiple System Atrophy. Ann Neurol. 2020 12; 88(6):1132-1143.
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Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies. JCI Insight. 2019 08 22; 4(16).
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Reply: Lysosomal storage disorder gene variants in multiple system atrophy. Brain. 2018 07 01; 141(7):e54.
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Medullary neuronal loss is not associated with a-synuclein burden in multiple system atrophy. Mov Disord. 2016 12; 31(12):1802-1809.
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Natural history of multiple system atrophy in the USA: a prospective cohort study. Lancet Neurol. 2015 Jul; 14(7):710-9.
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a-Synuclein pathology accumulates in sacral spinal visceral sensory pathways. Ann Neurol. 2015 Jul; 78(1):142-9.
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Expanding the spectrum of neuronal pathology in multiple system atrophy. Brain. 2015 Aug; 138(Pt 8):2293-309.
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Effects of deep brain stimulation in relatively young-onset multiple system atrophy Parkinsonism. J Neurol Sci. 2014 Jul 15; 342(1-2):42-4.
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The potential prognostic role of cardiovascular autonomic failure in a-synucleinopathies. Eur J Neurol. 2013 Feb; 20(2):231-5.