Neuroleptic Malignant Syndrome
"Neuroleptic Malignant Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Descriptor ID |
D009459
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| MeSH Number(s) |
C10.228.140.079.737 C10.720.737 C25.723.705.600
|
| Concept/Terms |
Neuroleptic Malignant Syndrome- Neuroleptic Malignant Syndrome
- Neuroleptic Malignant Syndromes
- Syndrome, Neuroleptic Malignant
- Syndromes, Neuroleptic Malignant
- NMS (Neuroleptic Malignant Syndrome)
- NMSs (Neuroleptic Malignant Syndrome)
Neuroleptic-Induced Neuroleptic Malignant Syndrome- Neuroleptic-Induced Neuroleptic Malignant Syndrome
- Neuroleptic Induced Neuroleptic Malignant Syndrome
- Neuroleptic-Malignant Syndrome, Neuroleptic Induced
- Neuroleptic Malignant Syndrome, Neuroleptic Induced
|
Below are MeSH descriptors whose meaning is more general than "Neuroleptic Malignant Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Neuroleptic Malignant Syndrome".
This graph shows the total number of publications written about "Neuroleptic Malignant Syndrome" by people in this website by year, and whether "Neuroleptic Malignant Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuroleptic Malignant Syndrome" by people in Profiles.
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An Evidence-Based Update on Anticholinergic Use for Drug-Induced Movement Disorders. CNS Drugs. 2024 04; 38(4):239-254.
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Neuroleptic Malignant Syndrome After Early Administration of Risperidone Long-Acting Injection. Prim Care Companion CNS Disord. 2017 Nov 30; 19(6).
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Evaluation and Management of Children With Acute Mental Health or Behavioral Problems. Part II: Recognition of Clinically Challenging Mental Health Related Conditions Presenting With Medical or Uncertain Symptoms. Pediatrics. 2016 09; 138(3).
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Catatonia and encephalopathy associated with paliperidone palmitate. J Clin Psychopharmacol. 2012 Apr; 32(2):284-5.
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When can patients with potentially life-threatening adverse effects be rechallenged with clozapine? A systematic review of the published literature. Schizophr Res. 2012 Feb; 134(2-3):180-6.
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Ecstasy intoxication: an overlap between serotonin syndrome and neuroleptic malignant syndrome. Clin Neuropharmacol. 1996 Apr; 19(2):157-64.
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Rhabdomyolysis and acute renal failure during high-dose haloperidol therapy. Ren Fail. 1995 Jul; 17(4):475-8.
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Rapid death during cocaine abuse: a variant of the neuroleptic malignant syndrome? Am J Drug Alcohol Abuse. 1988; 14(3):335-46.