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YONG XU

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1100 BATES
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Endocrinology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


    Collapse Research 
    Collapse research activities and funding
    R01DK139583     (XU, YONG)Sep 20, 2024 - Jul 31, 2029
    NIH
    Ano4 and Metabolic Health
    Role: Principal Investigator
    R01HD114146     (XU, YONG)Sep 12, 2024 - Jun 30, 2029
    NIH
    Trpc5-activated neural circuits and maternal behavior
    Role: Principal Investigator
    R01DK138123     (XU, YONG)Jul 11, 2024 - Apr 30, 2028
    NIH
    Forebrain Proenkaphalin Neurons Regulate Feeding
    Role: Principal Investigator
    R01DK138518     (XU, YONG)Jun 1, 2024 - Apr 30, 2028
    NIH
    A CHOLINERGIC NEUROCIRCUIT REGULATES FEEDING BEHAVIOR
    Role: Principal Investigator
    R01AG080392     (XU, YONG)Sep 15, 2023 - Jun 30, 2028
    NIH
    5-HT 2C Receptor and Alzheimer's Disease
    Role: Principal Investigator
    R01DK136479     (XU, YONG)Aug 25, 2023 - Apr 30, 2027
    NIH
    Neurobiology for Lac-Phe Hypophagia
    Role: Principal Investigator
    R01DK120858     (XU, YONG)Sep 15, 2020 - Jun 30, 2024
    NIH
    5-HT NEURONS INTEGRATE NEURAL INPUTS TO REGULATE FOOD INTAKE
    Role: Principal Investigator
    R01DK125480     (XU, YONG)Sep 15, 2020 - Jun 30, 2024
    NIH
    Brain Estrogen Regulates Energy and Glucose Balance
    Role: Principal Investigator
    R01DK115761     (FRAZER, ALAN)Sep 1, 2018 - May 31, 2022
    NIH
    Hypothalamic Grb10 and body weight
    Role: Co-Principal Investigator
    R01DK117281     (XU, YONG)Apr 1, 2018 - Mar 31, 2023
    NIH
    Neurobiology for the sex differences in energy balance
    Role: Principal Investigator
    R01DK101379     (XU, YONG)Sep 15, 2014 - Jul 31, 2018
    NIH
    Targeting hypothalamic steroid receptor co-activator-1 to treat obesity
    Role: Principal Investigator
    R01DK093587     (XU, YONG)Sep 27, 2011 - Aug 31, 2016
    NIH
    CNS Circuits Mediating Estrogenic Regulation on Energy and Glucose Homeostasis
    Role: Principal Investigator
    R00DK085330     (XU, YONG)Sep 20, 2010 - Aug 31, 2013
    NIH
    Hypothalamic mechanisms mediating estrogenic regulation of energy homeostasis
    Role: Principal Investigator
    K99DK085330     (XU, YONG)Sep 1, 2009 - Aug 31, 2010
    NIH
    Hypothalamic mechanisms mediating estrogenic regulation of energy homeostasis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Conde KM, Wong H, Fang S, Li Y, Yu M, Deng Y, Liu Q, Fang X, Wang M, Shi Y, Ginnard OZ, Yang Y, Tu L, Liu H, Liu H, Yin N, Bean JC, Han J, Burt ME, Jossy SV, Yang Y, Tong Q, Arenkiel BR, Wang C, He Y, Xu Y. Serotonin neurons integrate GABA and dopamine inputs to regulate meal initiation. Metabolism. 2025 Feb; 163:156099. PMID: 39667432.
      Citations:    Fields:    
    2. Yu M, Yin N, Feng B, Gao P, Yu K, Liu H, Liu H, Li Y, Ginnard OZ, Conde KM, Wang M, Fang X, Tu L, Bean JC, Liu Q, Deng Y, Yang Y, Han J, Jossy SV, Burt ML, Wong HZ, Yang Y, Arenkiel BR, He Y, Guo S, Gourdy P, Arnal JF, Lenfant F, Wang Z, Wang C, He Y, Xu Y. Identification of an ionic mechanism for ERa-mediated rapid excitation in neurons. Sci Adv. 2024 Oct 04; 10(40):eadp0696. PMID: 39356770; PMCID: PMC11446276.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Liu H, Bean JC, Li Y, Yu M, Ginnard OZ, Conde KM, Wang M, Fang X, Liu H, Tu L, Yin N, Han J, Yang Y, Tong Q, Arenkiel BR, Wang C, He Y, Xu Y. Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice. Nat Metab. 2024 Sep; 6(9):1775-1790. PMID: 39112722.
      Citations:    Fields:    Translation:AnimalsCells
    4. Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, Wang M, Bean JC, Han J, Scarcelli NA, Yang Y, Saito K, Cui H, Tong Q, Sun Z, Wang C, Cai X, Lu L, He Y, Xu Y, Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, Wang M, Bean JC, Han J, Scarcelli NA, Yang Y, Saito K, Cui H, Tong Q, Sun Z, Wang C, Cai X, Lu L, He Y, Xu Y. A Light-Responsive Neural Circuit Suppresses Feeding. J Neurosci. 2024 Jul 24; 44(30). PMID: 38897723; PMCID: PMC11270527.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Li Y, Cacciottolo TM, Yin N, He Y, Liu H, Liu H, Yang Y, Henning E, Keogh JM, Lawler K, Mendes de Oliveira E, Gardner EJ, Kentistou KA, Laouris P, Bounds R, Ong KK, Perry JRB, Barroso I, Tu L, Bean JC, Yu M, Conde KM, Wang M, Ginnard O, Fang X, Tong L, Han J, Darwich T, Williams KW, Yang Y, Wang C, Joss S, Firth HV, Xu Y, Farooqi IS. Loss of transient receptor potential channel 5 causes obesity and postpartum depression. Cell. 2024 Aug 08; 187(16):4176-4192.e17. PMID: 38959890.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    6. Liu H, He Y, Liu H, Brouwers B, Yin N, Lawler K, Keogh JM, Henning E, Lee DK, Yu M, Tu L, Zhang N, Conde KM, Han J, Yan Z, Scarcelli NA, Liao L, Xu J, Tong Q, Zheng H, Sun Z, Yang Y, Wang C, He Y, Farooqi IS, Xu Y. Neural circuits expressing the serotonin 2C receptor regulate memory in mice and humans. Sci Adv. 2024 Jun 28; 10(26):eadl2675. PMID: 38941473; PMCID: PMC11212768.
      Citations:    Fields:    Translation:HumansAnimalsCells
    7. Conde KM, Wong H, Fang S, Li Y, Yu M, Deng Y, Liu Q, Fang X, Wang M, Shi Y, Ginnard OZ, Yang Y, Tu L, Liu H, Liu H, Yin N, Bean JC, Han J, Burt ME, Jossy SV, Yang Y, Tong Q, Arenkiel BR, Wang C, He Y, Xu Y. 5-HT Neurons Integrate GABA and Dopamine Inputs to Regulate Meal Initiation. bioRxiv. 2024 Apr 29. PMID: 38746314; PMCID: PMC11092489.
      Citations:    
    8. Edwards GA, Wood CA, He Y, Nguyen Q, Kim PJ, Gomez-Gutierrez R, Park KW, Xu Y, Zurhellen C, Al-Ramahi I, Jankowsky JL. TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy. Acta Neuropathol. 2024 03 25; 147(1):61. PMID: 38526616.
      Citations: 6     Fields:    Translation:HumansAnimals
    9. Cai J, Jiang Y, Xu Y, Jiang Z, Young C, Li H, Ortiz-Guzman J, Zhuo Y, Li Y, Xu Y, Arenkiel BR, Tong Q. An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes. Neuron. 2024 Feb 07; 112(3):458-472.e6. PMID: 38056455; PMCID: PMC10922337.
      Citations:    Fields:    Translation:AnimalsCells
    10. Tu L, He Y, Xu Y. Anoctamin 4 defines glucose-inhibited neurons in the ventromedial hypothalamus. Neural Regen Res. 2024 Jun 01; 19(6):1177-1178. PMID: 37905852; PMCID: PMC11467938.
      Citations:    
    11. Conde K, Fang S, Xu Y. Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review. Cell Biosci. 2023 Aug 07; 13(1):143. PMID: 37550777; PMCID: PMC10408233.
      Citations: 1     
    12. Tu L, Bean JC, He Y, Liu H, Yu M, Liu H, Zhang N, Yin N, Han J, Scarcelli NA, Conde KM, Wang M, Li Y, Feng B, Gao P, Cai ZL, Fukuda M, Xue M, Tong Q, Yang Y, Liao L, Xu J, Wang C, He Y, Xu Y. Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia. J Clin Invest. 2023 07 17; 133(14). PMID: 37261917; PMCID: PMC10348766.
      Citations:    Fields:    Translation:AnimalsCells
    13. Xu Y, Jiang Z, Li H, Cai J, Jiang Y, Otiz-Guzman J, Xu Y, Arenkiel BR, Tong Q. Lateral septum as a melanocortin downstream site in obesity development. Cell Rep. 2023 05 30; 42(5):112502. PMID: 37171957; PMCID: PMC10317244.
      Citations:    Fields:    Translation:Humans
    14. Li H, Xu Y, Jiang Y, Jiang Z, Otiz-Guzman J, Morrill JC, Cai J, Mao Z, Xu Y, Arenkiel BR, Huang C, Tong Q. The melanocortin action is biased toward protection from weight loss in mice. Nat Commun. 2023 04 17; 14(1):2200. PMID: 37069175; PMCID: PMC10110624.
      Citations: 2     Fields:    Translation:Animals
    15. Han Y, He Y, Harris L, Xu Y, Wu Q. Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity. Elife. 2023 04 12; 12. PMID: 37043384; PMCID: PMC10097419.
      Citations: 1     Fields:    Translation:HumansCells
    16. Wang M, Yang Y, Xu Y. Brain nuclear receptors and cardiovascular function. Cell Biosci. 2023 Jan 20; 13(1):14. PMID: 36670468; PMCID: PMC9854230.
      Citations: 1     
    17. Liu H, He Y, Bai J, Zhang C, Zhang F, Yang Y, Luo H, Yu M, Liu H, Tu L, Zhang N, Yin N, Han J, Yan Z, Scarcelli NA, Conde KM, Wang M, Bean JC, Potts CHS, Wang C, Hu F, Liu F, Xu Y. Hypothalamic Grb10 enhances leptin signalling and promotes weight loss. Nat Metab. 2023 01; 5(1):147-164. PMID: 36593271.
      Citations: 2     Fields:    Translation:Animals
    18. He Y, Brouwers B, Liu H, Liu H, Lawler K, Mendes de Oliveira E, Lee DK, Yang Y, Cox AR, Keogh JM, Henning E, Bounds R, Perdikari A, Ayinampudi V, Wang C, Yu M, Tu L, Zhang N, Yin N, Han J, Scarcelli NA, Yan Z, Conde KM, Potts C, Bean JC, Wang M, Hartig SM, Liao L, Xu J, Barroso I, Mokrosinski J, Xu Y, Sadaf Farooqi I. Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior. Nat Med. 2022 12; 28(12):2537-2546. PMID: 36536256; PMCID: PMC9800280.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    19. Yu M, Bean JC, Liu H, He Y, Yang Y, Cai X, Yu K, Pei Z, Liu H, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, Han J, Scarcelli NA, Xu P, He Y, Xu Y, Wang C. SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis. Cell Biosci. 2022 Oct 09; 12(1):170. PMID: 36210455; PMCID: PMC9549684.
      Citations: 2     
    20. Pei Z, He Y, Bean JC, Yang Y, Liu H, Yu M, Yu K, Hyseni I, Cai X, Liu H, Qu N, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, Han J, Potts CH, Scarcelli NA, Yan Z, Xu P, Wu Q, He Y, Xu Y, Wang C. Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance. Front Endocrinol (Lausanne). 2022; 13:889122. PMID: 36120438; PMCID: PMC9471380.
      Citations:    
    21. Liu H, Cai X, He Y, Xu Y. Hyperactivity of a midbrain dopamine to 5-HT circuit causes anorexia. J Mol Cell Biol. 2022 08 26; 14(5). PMID: 35612989; PMCID: PMC9412745.
      Citations:    Fields:    
    22. Cai X, Liu H, Feng B, Yu M, He Y, Liu H, Liang C, Yang Y, Tu L, Zhang N, Wang L, Yin N, Han J, Yan Z, Wang C, Xu P, Wu Q, Tong Q, He Y, Xu Y. Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nat Neurosci. 2022 Jul; 25(7):976. PMID: 35729403.
      Citations:    Fields:    
    23. Li VL, He Y, Liu H, Kim JT, Wiggenhorn AL, Tanzo JT, Tung AS, Lyu X, Zushin PH, Jansen RS, Michael B, Loh KY, Yang AC, Carl CS, Voldstedlund CT, Wei W, Terrell SM, Moeller BC, Arthur RM, Wallis GA, van de Wetering K, Stahl A, Kiens B, Richter EA, Banik SM, Snyder MP, Xu Y, Long JZ, Contrepois K. An exercise-inducible metabolite that suppresses feeding and obesity. Nature. 2022 06; 606(7915):785-790. PMID: 35705806; PMCID: PMC9767481.
      Citations:    Fields:    Translation:Animals
    24. Tu L, Fukuda M, Tong Q, Xu Y. The ventromedial hypothalamic nucleus: watchdog of whole-body glucose homeostasis. Cell Biosci. 2022 May 26; 12(1):71. PMID: 35619170; PMCID: PMC9134642.
      Citations:    
    25. Cai X, Liu H, Feng B, Yu M, He Y, Liu H, Liang C, Yang Y, Tu L, Zhang N, Wang L, Yin N, Han J, Yan Z, Wang C, Xu P, Wu Q, Tong Q, He Y, Xu Y. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nat Neurosci. 2022 05; 25(5):646-658. PMID: 35501380; PMCID: PMC9926508.
      Citations:    Fields:    Translation:AnimalsCells
    26. Mishra I, Xie WR, Bournat JC, He Y, Wang C, Silva ES, Liu H, Ku Z, Chen Y, Erokwu BO, Jia P, Zhao Z, An Z, Flask CA, He Y, Xu Y, Chopra AR. Protein tyrosine phosphatase receptor d serves as the orexigenic asprosin receptor. Cell Metab. 2022 04 05; 34(4):549-563.e8. PMID: 35298903; PMCID: PMC8986618.
      Citations: 3     Fields:    Translation:Animals
    27. Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, Qu N, Hyseni I, Yu K, Jiang Y, Tong Q, Sun Z, Arenkiel BR, He Y, Xu P, Xu Y. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Sci Adv. 2022 Jan 21; 8(3):eabk0185. PMID: 35044814; PMCID: PMC8769556.
      Citations: 2     Fields:    
    28. Yang Y, He Y, Liu H, Zhou W, Wang C, Xu P, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Fukuda M, Tong Q, Xu J, Sun Z, O'Malley BW, Xu Y. Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Rep. 2021 12 07; 37(10):110075. PMID: 34879284; PMCID: PMC8715676.
      Citations:    Fields:    Translation:HumansAnimalsCells
    29. Yan Z, He Y, Cai X, Shu G, Xu Y. Eating for hunger or pleasure: a Serotonin Model. J Mol Cell Biol. 2021 12 06; 13(9):693-694. PMID: 34480567; PMCID: PMC8648382.
      Citations:    Fields:    Translation:HumansCells
    30. Yoo ES, Li L, Jia L, Lord CC, Lee CE, Birnbaum SG, Vianna CR, Berglund ED, Cunningham KA, Xu Y, Sohn JW, Liu C. Gai/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents. Cell Rep. 2021 11 16; 37(7):109997. PMID: 34788630; PMCID: PMC8636014.
      Citations:    Fields:    Translation:AnimalsCells
    31. Tu L, Zhang N, Conde KM, Bean JC, Wang C, Xu Y. Free-floating Immunostaining of Mouse Brains. J Vis Exp. 2021 10 07; (176). PMID: 34694284; PMCID: PMC8981791.
      Citations:    Fields:    Translation:AnimalsCells
    32. Zhu Y, Li N, Huang M, Bartels M, Zhao S, Chen X, Crewe C, Straub L, Vishvanath L, Zhang Z, Shao M, Yang Y, Gliniak CM, Gordillo R, Smith GI, Holland WL, Gupta RK, Dong B, Caron N, Xu Y, Akgul Y, Klein S, Scherer PE, Dogn? S. Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis. Nat Commun. 2021 08 10; 12(1):4829. PMID: 34376643; PMCID: PMC8355239.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    33. Zhang N, Yan Z, Liu H, Yu M, He Y, Liu H, Liang C, Tu L, Wang L, Yin N, Han J, Scarcelli N, Yang Y, Wang C, Zeng T, Chen LL, Xu Y. Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions. Front Physiol. 2021; 12:714104. PMID: 34393830; PMCID: PMC8355523.
      Citations: 2     
    34. He Y, Cai X, Liu H, Conde KM, Xu P, Li Y, Wang C, Yu M, He Y, Liu H, Liang C, Yang T, Yang Y, Yu K, Wang J, Zheng R, Liu F, Sun Z, Heisler L, Wu Q, Tong Q, Zhu C, Shu G, Xu Y. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding. Mol Psychiatry. 2021 12; 26(12):7211-7224. PMID: 34290371; PMCID: PMC8776930.
      Citations: 3     Fields:    Translation:Cells
    35. Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, Yang T, Zou K, Han Y, Amos CI, Xu Y, Chen L, Sun Z. Author Correction: REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 2021 Jul; 595(7865):E2. PMID: 34131305.
      Citations: 1     Fields:    
    36. Han Y, Xia G, Srisai D, Meng F, He Y, Ran Y, He Y, Farias M, Hoang G, Dietrich MO, Chen MH, Xu Y, Wu Q, T?th I. Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nat Commun. 2021 06 10; 12(1):3525. PMID: 34112797; PMCID: PMC8192783.
      Citations: 4     Fields:    Translation:AnimalsCells
    37. Kaneko K, Lin HY, Fu Y, Saha PK, De la Puente-Gomez AB, Xu Y, Ohinata K, Chen P, Morozov A, Fukuda M. Rap1 in the VMH regulates glucose homeostasis. JCI Insight. 2021 06 08; 6(11). PMID: 33974562; PMCID: PMC8262364.
      Citations: 3     Fields:    Translation:AnimalsCells
    38. Han Y, Xia G, He Y, He Y, Farias M, Xu Y, Wu Q. A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation. Sci Adv. 2021 05; 7(22). PMID: 34039606; PMCID: PMC10964976.
      Citations: 1     Fields:    Translation:HumansAnimals
    39. Ding Y, Liu Y, Lee DK, Tong Z, Yu X, Li Y, Xu Y, Lanz RB, O'Malley BW, Xu J. Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype. Proc Natl Acad Sci U S A. 2021 05 25; 118(21). PMID: 34006643; PMCID: PMC8166171.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    40. He Y, Liu H, Yin N, Yang Y, Wang C, Yu M, Liu H, Liang C, Wang J, Tu L, Zhang N, Wang L, He Y, Fukuda M, Wu Q, Sun Z, Tong Q, Xu Y. Barbadin Potentiates Long-Term Effects of Lorcaserin on POMC Neurons and Weight Loss. J Neurosci. 2021 06 30; 41(26):5734-5746. PMID: 34031163; PMCID: PMC8244968.
      Citations: 1     Fields:    Translation:AnimalsCells
    41. Fan S, Xu Y, Lu Y, Jiang Z, Li H, Morrill JC, Cai J, Wu Q, Xu Y, Xue M, Arenkiel BR, Huang C, Tong Q. A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia. Nat Commun. 2021 05 11; 12(1):2662. PMID: 33976218; PMCID: PMC8113586.
      Citations: 3     Fields:    Translation:AnimalsCells
    42. Mishra I, Duerrschmid C, Ku Z, He Y, Xie W, Silva ES, Hoffman J, Xin W, Zhang N, Xu Y, An Z, Chopra AR. Asprosin-neutralizing antibodies as a treatment for metabolic syndrome. Elife. 2021 04 27; 10. PMID: 33904407; PMCID: PMC8102062.
      Citations: 6     Fields:    Translation:HumansAnimals
    43. Liu T, Xu Y, Yi CX, Tong Q, Cai D. The hypothalamus for whole-body physiology: from metabolism to aging. Protein Cell. 2022 06; 13(6):394-421. PMID: 33826123; PMCID: PMC9095790.
      Citations: 7     Fields:    Translation:Humans
    44. Xia G, Han Y, Meng F, He Y, Srisai D, Farias M, Dang M, Palmiter RD, Xu Y, Wu Q. Reciprocal control of obesity and anxiety-depressive disorder via a GABA and serotonin neural circuit. Mol Psychiatry. 2021 07; 26(7):2837-2853. PMID: 33767348; PMCID: PMC8505263.
      Citations: 5     Fields:    Translation:Humans
    45. Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, Yang T, Zou K, Han Y, Amos CI, Xu Y, Chen L, Sun Z. REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 2021 04; 592(7856):763-767. PMID: 33762728; PMCID: PMC8085086.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    46. Wang Y, Yang Y, Wang M, Wang S, Jeong JM, Xu L, Wen Y, Emontzpohl C, Atkins CL, Duong K, Moreno NF, Yuan X, Hall DR, Dar W, Feng D, Gao B, Xu Y, Czigany Z, Colgan SP, Bynon JS, Akira S, Brown JM, Eltzschig HK, Jacobsen EA, Ju C. Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production. Sci Transl Med. 2021 02 03; 13(579). PMID: 33536281; PMCID: PMC8167890.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    47. Liu H, He Y, Beck J, da Silva Teixeira S, Harrison K, Xu Y, Sisley S. Defining vitamin D receptor expression in the brain using a novel VDRCre mouse. J Comp Neurol. 2021 06; 529(9):2362-2375. PMID: 33368246; PMCID: PMC8053677.
      Citations: 5     Fields:    Translation:Animals
    48. Wang C, Zhou W, He Y, Yang T, Xu P, Yang Y, Cai X, Wang J, Liu H, Yu M, Liang C, Yang T, Liu H, Fukuda M, Tong Q, Wu Q, Sun Z, He Y, Xu Y. AgRP neurons trigger long-term potentiation and facilitate food seeking. Transl Psychiatry. 2021 01 05; 11(1):11. PMID: 33414382; PMCID: PMC7791100.
      Citations: 5     Fields:    Translation:AnimalsCells
    49. Liu H, Wang C, Yu M, Yang Y, He Y, Liu H, Liang C, Tu L, Zhang N, Wang L, Wang J, Liu F, Hu F, Xu Y. TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner. Endocrinology. 2021 01 01; 162(1). PMID: 33034617; PMCID: PMC7685027.
      Citations: 2     Fields:    Translation:AnimalsCells
    50. Zhang Z, Reis FMCV, He Y, Park JW, DiVittorio JR, Sivakumar N, van Veen JE, Maesta-Pereira S, Shum M, Nichols I, Massa MG, Anderson S, Paul K, Liesa M, Ajijola OA, Xu Y, Adhikari A, Correa SM. Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice. Nat Commun. 2020 12 11; 11(1):6378. PMID: 33311503; PMCID: PMC7732979.
      Citations: 13     Fields:    Translation:AnimalsCells
    51. Yang Y, Xu Y. The central melanocortin system and human obesity. J Mol Cell Biol. 2020 10 01; 12(10):785-797. PMID: 32976556; PMCID: PMC7816681.
      Citations: 5     Fields:    Translation:HumansAnimals
    52. Liu H, Xu Y, Hu F. AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis. Front Endocrinol (Lausanne). 2020; 11:578830. PMID: 33071984; PMCID: PMC7538541.
      Citations: 6     Fields:    Translation:HumansAnimals
    53. Fu Y, Kaneko K, Lin HY, Mo Q, Xu Y, Suganami T, Ravn P, Fukuda M. Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus. Endocrinology. 2020 09 01; 161(9). PMID: 32603429; PMCID: PMC7410368.
      Citations: 9     Fields:    Translation:AnimalsCells
    54. Sun Z, Xu Y. Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain. Endocrinology. 2020 08 01; 161(8). PMID: 32449767; PMCID: PMC7351129.
      Citations: 9     Fields:    Translation:HumansAnimals
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    123. Xu Y, Jones JE, Lauzon DA, Anderson JG, Balthasar N, Heisler LK, Zinn AR, Lowell BB, Elmquist JK. A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. J Neurosci. 2010 Nov 03; 30(44):14630-4. PMID: 21048120; PMCID: PMC3466475.
      Citations: 41     Fields:    Translation:Animals
    124. Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nat Neurosci. 2010 Dec; 13(12):1457-9. PMID: 21037584; PMCID: PMC3059249.
      Citations: 51     Fields:    Translation:AnimalsCells
    125. Xu Y, Hill JW, Fukuda M, Gautron L, Sohn JW, Kim KW, Lee CE, Choi MJ, Lauzon DA, Dhillon H, Lowell BB, Zigman JM, Zhao JJ, Elmquist JK. PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metab. 2010 Jul 07; 12(1):88-95. PMID: 20620998; PMCID: PMC2919367.
      Citations: 57     Fields:    Translation:AnimalsCells
    126. Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, Chua S, Scherer PE, Lowell BB, Elmquist JK, Br?ning JC. Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab. 2010 Apr 07; 11(4):286-97. PMID: 20374961; PMCID: PMC2854520.
      Citations: 191     Fields:    Translation:AnimalsCells
    127. Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK. Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Endocrinology. 2009 Nov; 150(11):4874-82. PMID: 19819947; PMCID: PMC2775989.
      Citations: 49     Fields:    Translation:AnimalsCells
    128. Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, Lowell BB, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 2008 Nov 26; 60(4):582-9. PMID: 19038216; PMCID: PMC2631191.
      Citations: 131     Fields:    Translation:Animals
    129. Xu Y, Krukoff TL. Adrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: roles of calcium and phosphatases. Mol Pharmacol. 2007 Jul; 72(1):112-20. PMID: 17446268.
      Citations: 12     Fields:    Translation:AnimalsCells
    130. Xu Y, Krukoff TL. Adrenomedullin in the rostral ventrolateral medulla inhibits baroreflex control of heart rate: a role for protein kinase A. Br J Pharmacol. 2006 May; 148(1):70-7. PMID: 16501581; PMCID: PMC1617038.
      Citations: 4     Fields:    Translation:Animals
    131. Xu Y, Krukoff TL. Adrenomedullin stimulates nitric oxide release from SK-N-SH human neuroblastoma cells by modulating intracellular calcium mobilization. Endocrinology. 2005 May; 146(5):2295-305. PMID: 15677761.
      Citations: 5     Fields:    Translation:HumansCells
    132. Xu Y, Krukoff TL. Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus is mediated by nitric oxide and GABA. Regul Pept. 2004 Jun 15; 119(1-2):21-30. PMID: 15093693; PMCID: PMC4820401.
      Citations: 8     Fields:    Translation:AnimalsCells
    133. Xu Y, Krukoff TL. Adrenomedullin in the rostral ventrolateral medulla increases arterial pressure and heart rate: roles of glutamate and nitric oxide. Am J Physiol Regul Integr Comp Physiol. 2004 Oct; 287(4):R729-34. PMID: 15178541; PMCID: PMC4820402.
      Citations: 10     Fields:    Translation:AnimalsCells
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