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ATUL CHOPRA

TitleAdjunct Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
Address11407 Euclid Ave, Floor 2
Cleveland, OH 77030
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    Collapse Research 
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    R01DK130931     (CHOPRA, ATUL)Jul 23, 2022 - Jun 30, 2026
    NIH
    The CNS Receptor For Asprosin
    Role: Principal Investigator
    R01DK125403     (CHOPRA, ATUL ;LIU, SIMIN ;SUN, QI)Jul 1, 2020 - Mar 31, 2024
    NIH
    Asprosin, body weight, and risk of type 2 diabetes in U.S. men and women
    Role: Co-Principal Investigator
    R01DK118290     (CHOPRA, ATUL)Sep 10, 2018 - Jun 30, 2023
    NIH
    ASPROSIN NEUTRALIZATION AS A NOVEL ANTI-OBESITY TREATMENT
    Role: Principal Investigator
    K08DK102529     (CHOPRA, ATUL)Jul 15, 2014 - Apr 30, 2020
    NIH
    The Role of FBN1 in mammalian energy balance
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mishra I, Feng B, Basu B, Brown AM, Kim LH, Lin T, Raza MA, Moore A, Hahn A, Bailey S, Sharp A, Bournat JC, Poulton C, Kim B, Langsner A, Sathyanesan A, Sillitoe RV, He Y, Chopra AR. The cerebellum modulates thirst. Nat Neurosci. 2024 Sep; 27(9):1745-1757. PMID: 38987435.
      Citations:    Fields:    Translation:AnimalsCells
    2. Mishra I, Chopra AR. Overexpression and ELISA-based detection of asprosin in cultured cells and mice. STAR Protoc. 2022 12 16; 3(4):101762. PMID: 36240062; PMCID: PMC9568886.
      Citations:    Fields:    
    3. Mishra I, Xie WR, Bournat JC, He Y, Wang C, Silva ES, Liu H, Ku Z, Chen Y, Erokwu BO, Jia P, Zhao Z, An Z, Flask CA, He Y, Xu Y, Chopra AR. Protein tyrosine phosphatase receptor d serves as the orexigenic asprosin receptor. Cell Metab. 2022 04 05; 34(4):549-563.e8. PMID: 35298903; PMCID: PMC8986618.
      Citations: 3     Fields:    Translation:Animals
    4. Basu B, Jain M, Chopra AR. Caudamins, a new subclass of protein hormones. Trends Endocrinol Metab. 2021 12; 32(12):1007-1014. PMID: 34666940; PMCID: PMC8585694.
      Citations:    Fields:    Translation:Humans
    5. Mishra I, Duerrschmid C, Ku Z, He Y, Xie W, Silva ES, Hoffman J, Xin W, Zhang N, Xu Y, An Z, Chopra AR. Asprosin-neutralizing antibodies as a treatment for metabolic syndrome. Elife. 2021 04 27; 10. PMID: 33904407; PMCID: PMC8102062.
      Citations: 6     Fields:    Translation:HumansAnimals
    6. Hoffmann JG, Xie W, Chopra AR. Energy Regulation Mechanism and Therapeutic Potential of Asprosin. Diabetes. 2020 04; 69(4):559-566. PMID: 32198197; PMCID: PMC7085243.
      Citations: 5     Fields:    Translation:HumansAnimals
    7. Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, Saha PK, Lee ME, Phillips KJ, Jain M, Jia P, Zhao Z, Farias M, Wu Q, Milewicz DM, Sutton VR, Moore DD, Butte NF, Krashes MJ, Xu Y, Chopra AR. Asprosin is a centrally acting orexigenic hormone. Nat Med. 2017 Dec; 23(12):1444-1453. PMID: 29106398; PMCID: PMC5720914.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    8. Romere C, Duerrschmid C, Bournat J, Constable P, Jain M, Xia F, Saha PK, Del Solar M, Zhu B, York B, Sarkar P, Rendon DA, Gaber MW, LeMaire SA, Coselli JS, Milewicz DM, Sutton VR, Butte NF, Moore DD, Chopra AR. Asprosin, a Fasting-Induced Glucogenic Protein Hormone. Cell. 2016 Apr 21; 165(3):566-79. PMID: 27087445; PMCID: PMC4852710.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    9. Wangler MF, Gonzaga-Jauregui C, Gambin T, Penney S, Moss T, Chopra A, Probst FJ, Xia F, Yang Y, Werlin S, Eglite I, Kornejeva L, Bacino CA, Baldridge D, Neul J, Lehman EL, Larson A, Beuten J, Muzny DM, Jhangiani S, Baylor-Hopkins Center for Mendelian Genomics, Gibbs RA, Lupski JR, Beaudet A. Heterozygous de novo and inherited mutations in the smooth muscle actin (ACTG2) gene underlie megacystis-microcolon-intestinal hypoperistalsis syndrome. PLoS Genet. 2014 Mar; 10(3):e1004258. PMID: 24676022; PMCID: PMC3967950.
      Citations: 50     Fields:    Translation:Humans
    10. York B, Tsimelzon A, Louet JF, Chopra AR, Reineke EL, Zhou S, Stevens RD, Wenner BR, Ilkayeva O, Bain JR, Xu J, Hilsenbeck SG, Newgard CB, O'Malley BW, Sagen JV. Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. Mol Endocrinol. 2013 Feb; 27(2):366-80. PMID: 23315938; PMCID: PMC3683811.
      Citations: 16     Fields:    Translation:Animals
    11. York B, Reineke EL, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW, Sagen JV. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metab. 2012 May 02; 15(5):752-63. PMID: 22560224; PMCID: PMC3349072.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    12. Chopra AR, Kommagani R, Saha P, Louet JF, Salazar C, Song J, Jeong J, Finegold M, Viollet B, DeMayo F, Chan L, Moore DD, O'Malley BW. Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab. 2011 Jan 05; 13(1):35-43. PMID: 21195347; PMCID: PMC3072049.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    13. Louet JF, Chopra AR, Sagen JV, An J, York B, Tannour-Louet M, Saha PK, Stevens RD, Wenner BR, Ilkayeva OR, Bain JR, Zhou S, DeMayo F, Xu J, Newgard CB, O'Malley BW. The coactivator SRC-1 is an essential coordinator of hepatic glucose production. Cell Metab. 2010 Dec 01; 12(6):606-18. PMID: 21109193; PMCID: PMC3024581.
      Citations: 37     Fields:    Translation:AnimalsCells
    14. Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH. Foxa2-dependent hepatic gene regulatory networks depend on physiological state. Physiol Genomics. 2009 Jul 09; 38(2):186-95. PMID: 19417011; PMCID: PMC2712224.
      Citations: 12     Fields:    Translation:AnimalsCells
    15. Chopra AR, Louet JF, Saha P, An J, Demayo F, Xu J, York B, Karpen S, Finegold M, Moore D, Chan L, Newgard CB, O'Malley BW. Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science. 2008 Nov 28; 322(5906):1395-9. PMID: 19039140; PMCID: PMC2668604.
      Citations: 96     Fields:    Translation:AnimalsCells
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