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JOSEPH COSELLI

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address6770 BERTNER AVE SUITE C330,C1095
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    Collapse Overview 
    Collapse overview
    Dr. Coselli is an innovator and a leader in his field and he is highly experienced in complex aortic repair, such as repair performed in patients with connective tissue disorders (such as Marfan and Loeys-Dietz syndromes), as well as emergent repair performed in patients with conditions such as acute aortic dissection or aortic rupture. For example, many patients with Marfan syndrome and annuloaortic ectasia are suitable for valve-sparing aortic root replacement, which obviates the need for a life-long anticoagulation regimen.

    Dr. Coselli has investigated methods to reduce postoperative mortality, paralysis, and stroke; his success in improving the process of aortic repair has resulted in better patient outcomes than those achieved in previous eras. Additionally, whenever feasible, Dr. Coselli has utilized endovascular technology to repair aortic aneurysms, because many limited aneurysms may be repaired by using thoracic stent-grafts. Encouraged by the results achieved in Europe, Dr. Coselli is currently participating in clinical trials involving the transcatheter implantation of aortic valve replacement (TAVR) devices. Dr. Coselli is especially attuned to the needs of international patients, and he routinely provides expert care to patients throughout the world. He has performed more than 7,000 surgical repairs of the aorta and nearly 3,000 open repairs of the thoracoabdominal aorta, for which he is the world’s most experienced surgeon.

    The future of aortic surgery will undoubtedly be heavily influenced by advancements in multiple disciplines―genetics, cellular biology, biochemistry, engineering, and bioinformatics―as well as by innovations in imaging and in surgical and endovascular technology. Dr. Coselli continuously seeks out new treatment paradigms and has participated in numerous investigator-initiated and industry-sponsored research projects. Additionally, he has published several key papers describing the outcomes of clinical studies designed to determine the best approaches to preventing complications during aortic repair. These papers report the benefits of using cerebrospinal fluid drainage to protect the spinal cord (a technique now in widespread use in aortic repair), renal perfusion as a protective measure against renal ischemia, and left heart bypass as a protective measure against distal ischemia. Additionally, by routinely presenting informative academic lectures throughout the world, Dr. Coselli has disseminated the latest approach to surgical repairs of the aortic root (valve-sparing outcomes), aortic arch (Y-graft outcomes), and thoracoabdominal aorta (selecting adjuncts by extent of repair).

    Mentored by the legendary aortic surgeon, Dr. E. Stanley Crawford, Dr. Coselli is today one of the world’s most experienced aortic surgeons and best known as the foremost expert in thoracoabdominal aortic aneurysm repair—he recently published a milestone paper describing results after 3309 such repairs. He has an extensive clinical database and encourages participation in clinical research by designing research projects based on specific interests within aortic surgery. With approval, access to de-identified data from the Aortic Surgery clinical database may be granted. Dr. Coselli routinely publishes on a wide variety of aortic topics, and several outstanding papers and presentations have been prepared by residents, fellows, and students. Key publications have influenced clinical practice trends by determining the best approaches towards preventing complications during aortic repair. Regarding thoracoabdominal aortic aneurysm repair, randomized clinical trials were conducted to establish the benefits of using cerebrospinal fluid drainage to protect the spinal cord (a technique now in widespread use in aortic repair) and renal perfusion as a protective measure against renal ischemia as well as performing retrospective analysis of left heart bypass as a protective measure against distal ischemia. Additionally, by routinely presenting informative academic lectures throughout the world, Dr. Coselli has disseminated the latest approach to surgical repairs of the aortic root (valve-sparing approaches, including those is patients with Marfan syndrome), aortic arch (Y-graft approaches, hybrid procedures), and thoracoabdominal aortic aneurysm repair (postoperative quality of life in patients with Marfan syndrome). Dr. Coselli continuously seeks out new treatment paradigms and participates in numerous investigator-initiated and industry-sponsored research projects conducted at Baylor College of Medicine and the Texas Heart Institute; studies include the use of transcatheter aortic valve replacement, rapid-deployment sutureless aortic valves, and a wide variety of stent-grafts.



    Collapse Research 
    Collapse research activities and funding
    R01HL085341     (LEMAIRE, SCOTT A)Sep 30, 2008 - Jun 30, 2013
    NIH
    Extracellular Matrix Metabolism in Thoracic Aortic Aneurysm and Dissection
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nichols A, Blackburn KW, Glover VA, Nguyen LH, Etheridge GM, Green SY, Barron LK, Xue AH, Chatterjee S, Orozco-Sevilla V, Moon MR, Coselli JS. Outcomes of thoracoabdominal aortic aneurysm repair in patients with and without peripheral arterial disease. J Thorac Cardiovasc Surg. 2025 11; 170(5):1371-1378.e6. PMID: 40112948.
      Citations:    Fields:    Translation:Humans
    2. Coselli JS, Barron LM. Lifetime Aortic Management in?Marfan?Syndrome: Puzzle Pieces and Rare Diseases. J Am Coll Cardiol. 2023 09 12; 82(11):1077-1079. PMID: 37673509.
      Citations:    Fields:    Translation:Humans
    3. Chakraborty A, Li Y, Zhang C, Li Y, Rebello KR, Li S, Xu S, Vasquez HG, Zhang L, Luo W, Wang G, Chen K, Coselli JS, LeMaire SA, Shen YH. Epigenetic Induction of Smooth Muscle Cell Phenotypic Alterations in Aortic Aneurysms and Dissections. Circulation. 2023 09 19; 148(12):959-977. PMID: 37555319; PMCID: PMC10529114.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    4. Coselli JS, LeMaire SA, Orozco-Sevilla V, Preventza O, Moon MR, Barron LM, Chatterjee S. Current approaches to spinal cord protection during open thoracoabdominal aortic aneurysm repair. Ann Cardiothorac Surg. 2023 Sep 28; 12(5):429-437. PMID: 37817849; PMCID: PMC10561332.
      Citations: 4     
    5. Zhang C, Li Y, Chakraborty A, Li Y, Rebello KR, Ren P, Luo W, Zhang L, Lu HS, Cassis LA, Coselli JS, Daugherty A, LeMaire SA, Shen YH. Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in Mice. Arterioscler Thromb Vasc Biol. 2023 02; 43(2):234-252. PMID: 36579645; PMCID: PMC9877188.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    6. Dawson A, Li Y, Li Y, Ren P, Vasquez HG, Zhang C, Rebello KR, Ageedi W, Azares AR, Mattar AB, Sheppard MB, Lu HS, Coselli JS, Cassis LA, Daugherty A, Shen YH, LeMaire SA. Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-? Signaling. Genes (Basel). 2021 12 30; 13(1). PMID: 35052435; PMCID: PMC8774900.
      Citations: 23     Fields:    Translation:HumansCells
    7. Li Y, Ren P, Dawson A, Vasquez HG, Ageedi W, Zhang C, Luo W, Chen R, Li Y, Kim S, Lu HS, Cassis LA, Coselli JS, Daugherty A, Shen YH, LeMaire SA. Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue. Circulation. 2020 10 06; 142(14):1374-1388. PMID: 33017217; PMCID: PMC7539140.
      Citations: 170     Fields:    Translation:Humans
    8. Luo W, Wang Y, Zhang L, Ren P, Zhang C, Li Y, Azares AR, Zhang M, Guo J, Ghaghada KB, Starosolski ZA, Rajapakshe K, Coarfa C, Li Y, Chen R, Fujiwara K, Abe JI, Coselli JS, Milewicz DM, LeMaire SA, Shen YH. Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture. Circulation. 2020 01 07; 141(1):42-66. PMID: 31887080; PMCID: PMC6939474.
      Citations: 145     Fields:    Translation:AnimalsCells
    9. Romere C, Duerrschmid C, Bournat J, Constable P, Jain M, Xia F, Saha PK, Del Solar M, Zhu B, York B, Sarkar P, Rendon DA, Gaber MW, LeMaire SA, Coselli JS, Milewicz DM, Sutton VR, Butte NF, Moore DD, Chopra AR. Asprosin, a Fasting-Induced Glucogenic Protein Hormone. Cell. 2016 Apr 21; 165(3):566-79. PMID: 27087445; PMCID: PMC4852710.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    10. Preventza O, Garcia A, Tuluca A, Henry M, Cooley DA, Simpson K, Bakaeen FG, Cornwell LD, Omer S, Coselli JS. Innominate artery cannulation for proximal aortic surgery: outcomes and neurological events in 263 patients. Eur J Cardiothorac Surg. 2015 Dec; 48(6):937-42; discussion 942. PMID: 25646398.
      Citations: 8     Fields:    Translation:Humans
    11. Aftab M, Songdechakraiwut T, Green SY, Zarda S, Price MD, Nalty CC, Preventza O, de la Cruz KI, LeMaire SA, Coselli JS. Contemporary outcomes of open thoracoabdominal aortic aneurysm repair in octogenarians. J Thorac Cardiovasc Surg. 2015 Feb; 149(2 Suppl):S134-41. PMID: 25439781.
      Citations: 5     Fields:    Translation:Humans
    12. Coselli JS, Green SY, Zarda S, Nalty CC, Price MD, Hughes MS, Preventza O, de la Cruz KI, LeMaire SA. Outcomes of open distal aortic aneurysm repair in patients with chronic DeBakey type I dissection. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2986-93.e1-2. PMID: 25212053.
      Citations: 1     Fields:    Translation:Humans
    13. Reardon MJ, Adams DH, Coselli JS, Deeb GM, Kleiman NS, Chetcuti S, Yakubov SJ, Heimansohn D, Hermiller J, Hughes GC, Harrison JK, Khabbaz K, Tadros P, Zorn GL, Merhi W, Heiser J, Petrossian G, Robinson N, Maini B, Mumtaz M, Lee JS, Gleason TG, Resar J, Conte J, Watson D, Chenoweth S, Popma JJ, CoreValve US Clinical Investigators. Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2869-76.e1-7. PMID: 25152474.
      Citations: 6     Fields:    Translation:Humans
    14. Preventza O, Garcia A, Cooley DA, Tuluca A, Simpson KH, Bakaeen FG, Omer S, Cornwell L, Rosengart TK, Coselli JS. Reoperations on the total aortic arch in 119 patients: short- and mid-term outcomes, focusing on composite adverse outcomes and survival analysis. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2967-72. PMID: 25152482.
      Citations: 4     Fields:    Translation:Humans
    15. Aftab M, Coselli JS. Renal and visceral protection in thoracoabdominal aortic surgery. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2963-6. PMID: 25135232.
      Citations: 5     Fields:    Translation:Humans
    16. Coselli JS, Green SY. Innovation and instrumentation: endovascular repair of the aortic arch. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1717-8. PMID: 24768098.
      Citations: 1     Fields:    Translation:Humans
    17. Albini P, Barshes NR, Russell L, Wu D, Coselli JS, Shen YH, Allison PM, LeMaire SA. D-dimer levels remain elevated in acute aortic dissection after 24?h. J Surg Res. 2014 Sep; 191(1):58-63. PMID: 24791646.
      Citations: 2     Fields:    Translation:Humans
    18. Preventza O, Mohammed S, Cheong BY, Gonzalez L, Ouzounian M, Livesay JJ, Cooley DA, Coselli JS. Endovascular therapy in patients with genetically triggered thoracic aortic disease: applications and short- and mid-term outcomes. Eur J Cardiothorac Surg. 2014 Aug; 46(2):248-53; discussion 253. PMID: 24477738.
      Citations: 6     Fields:    Translation:Humans
    19. Yan TD, Tian DH, LeMaire SA, Misfeld M, Elefteriades JA, Chen EP, Hughes GC, Kazui T, Griepp RB, Kouchoukos NT, Bannon PG, Underwood MJ, Mohr FW, Oo A, Sundt TM, Bavaria JE, Di Bartolomeo R, Di Eusanio M, Roselli EE, Beyersdorf F, Carrel TP, Corvera JS, Della Corte A, Ehrlich M, Hoffman A, Jakob H, Matalanis G, Numata S, Patel HJ, Pochettino A, Safi HJ, Estrera A, Perreas KG, Sinatra R, Trimarchi S, Sun LZ, Tabata M, Wang C, Haverich A, Shrestha M, Okita Y, Coselli J. The ARCH Projects: design and rationale (IAASSG 001). Eur J Cardiothorac Surg. 2014 Jan; 45(1):10-6. PMID: 24296985.
      Citations: 5     Fields:    Translation:Humans
    20. Preventza O, Cervera R, Cooley DA, Bakaeen FG, Mohamed AS, Cheong BY, Cornwell L, Simpson KH, Coselli JS. Acute type I aortic dissection: traditional versus hybrid repair with antegrade stent delivery to the descending thoracic aorta. J Thorac Cardiovasc Surg. 2014 Jul; 148(1):119-25. PMID: 24041767.
      Citations: 6     Fields:    Translation:Humans
    21. Preventza O, Al-Najjar R, Lemaire SA, Weldon S, Coselli JS. Total arch replacement with frozen elephant trunk technique. Ann Cardiothorac Surg. 2013 Sep; 2(5):649-52. PMID: 24109576; PMCID: PMC3791205.
      Citations: 2     
    22. Wu D, Shen YH, Russell L, Coselli JS, LeMaire SA. Molecular mechanisms of thoracic aortic dissection. J Surg Res. 2013 Oct; 184(2):907-24. PMID: 23856125; PMCID: PMC3788606.
      Citations: 70     Fields:    Translation:HumansCells
    23. Preventza O, Aftab M, Coselli JS. Hybrid techniques for complex aortic arch surgery. Tex Heart Inst J. 2013; 40(5):568-71. PMID: 24391324; PMCID: PMC3853841.
      Citations: 4     Fields:    Translation:Humans
    24. Zou S, Ren P, Nguyen M, Coselli JS, Shen YH, LeMaire SA. Notch signaling in descending thoracic aortic aneurysm and dissection. PLoS One. 2012; 7(12):e52833. PMID: 23300792; PMCID: PMC3530510.
      Citations: 16     Fields:    Translation:HumansCells
    25. Shen YH, Zhang L, Ren P, Nguyen MT, Zou S, Wu D, Wang XL, Coselli JS, LeMaire SA. AKT2 confers protection against aortic aneurysms and dissections. Circ Res. 2013 Feb 15; 112(4):618-32. PMID: 23250987; PMCID: PMC3586338.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    26. Ren P, Zhang L, Xu G, Palmero LC, Albini PT, Coselli JS, Shen YH, LeMaire SA. ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections. Ann Thorac Surg. 2013 Feb; 95(2):570-7. PMID: 23245439; PMCID: PMC3593585.
      Citations: 38     Fields:    Translation:Humans
    27. de la Cruz KI, LeMaire SA, Weldon SA, Coselli JS. Thoracoabdominal aortic aneurysm repair with a branched graft. Ann Cardiothorac Surg. 2012 Sep; 1(3):381-93. PMID: 23977524; PMCID: PMC3741776.
      Citations: 6     
    28. Shen YH, Hu X, Zou S, Wu D, Coselli JS, LeMaire SA. Stem cells in thoracic aortic aneurysms and dissections: potential contributors to aortic repair. Ann Thorac Surg. 2012 May; 93(5):1524-33. PMID: 22440369; PMCID: PMC3423336.
      Citations: 12     Fields:    Translation:HumansCells
    29. Price MD, Parenti JL, Johnson ML, Lay AD, Preventza O, Huh J, Coselli JS, LeMaire SA. Early outcomes after aortic arch replacement by using the Y-graft technique. Ann Thorac Surg. 2011 Mar; 91(3):700-7; discussion 707-8. PMID: 21352982.
      Citations: 19     Fields:    Translation:Humans
    30. Li XN, Song J, Zhang L, LeMaire SA, Hou X, Zhang C, Coselli JS, Chen L, Wang XL, Zhang Y, Shen YH. Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin. Diabetes. 2009 Oct; 58(10):2246-57. PMID: 19592618; PMCID: PMC2750236.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    31. Li X, Rong Y, Zhang M, Wang XL, LeMaire SA, Coselli JS, Zhang Y, Shen YH. Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells. Biochem Biophys Res Commun. 2009 Apr 17; 381(4):660-5. PMID: 19254690; PMCID: PMC2677205.
      Citations: 50     Fields:    Translation:HumansCells
    32. Lin PH, Huynh TT, Kougias P, Wall MJ, Coselli JS, Mattox KL. Endovascular repair of traumatic thoracic aortic injuries: a critical appraisal. Asian Cardiovasc Thorac Ann. 2008 Aug; 16(4):337-45. PMID: 18670033.
      Citations: 1     Fields:    Translation:Humans
    33. Lin PH, Bechara C, Kougias P, Huynh TT, LeMaire SA, Coselli JS. Assessment of aortic pathology and peripheral arterial disease using multidetector computed tomographic angiography. Vasc Endovascular Surg. 2008 Dec-2009 Jan; 42(6):583-98. PMID: 18621886.
      Citations: 6     Fields:    Translation:Humans
    34. Zhang MX, Zhang C, Shen YH, Wang J, Li XN, Chen L, Zhang Y, Coselli JS, Wang XL. Effect of 27nt small RNA on endothelial nitric-oxide synthase expression. Mol Biol Cell. 2008 Sep; 19(9):3997-4005. PMID: 18614799; PMCID: PMC2526692.
      Citations: 22     Fields:    Translation:HumansCells
    35. Lin PH, Huynh TT, Kougias P, Huh J, LeMaire SA, Coselli JS. Descending thoracic aortic dissection: evaluation and management in the era of endovascular technology. Vasc Endovascular Surg. 2009 Feb-Mar; 43(1):5-24. PMID: 18583304.
      Citations: 3     Fields:    Translation:Humans
    36. Zhang C, Zhang MX, Shen YH, Burks JK, Li XN, LeMaire SA, Yoshimura K, Aoki H, Matsuzaki M, An FS, Engler DA, Coselli JS, Zhang Y, Wang XL, Matsunami RK. Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1. Biochim Biophys Acta. 2008 Aug; 1783(8):1517-28. PMID: 18439917; PMCID: PMC2587084.
      Citations: 7     Fields:    Translation:HumansCells
    37. Lin PH, Barshes NR, Albo D, Kougias P, Berger DH, Huynh TT, LeMaire SA, Dardik A, Lee WA, Coselli JS. Concomitant colorectal cancer and abdominal aortic aneurysm: evolution of treatment paradigm in the endovascular era. J Am Coll Surg. 2008 May; 206(5):1065-73; discussion 1074-5. PMID: 18471757.
      Citations: 10     Fields:    Translation:Humans
    38. Lin PH, Kougias P, Huynh TT, Huh J, Coselli JS. Endovascular repair of ascending aortic pseudoaneurysm: technical considerations of a common carotid artery approach using the Zenith aortic cuff endograft. J Endovasc Ther. 2007 Dec; 14(6):794-8. PMID: 18052591.
      Citations: 6     Fields:    Translation:Humans
    39. Daniel JC, Huynh TT, Zhou W, Kougias P, El Sayed HF, Huh J, Coselli JS, Lin PH, LeMaire SA. Acute aortic dissection associated with use of cocaine. J Vasc Surg. 2007 Sep; 46(3):427-33. PMID: 17826227.
      Citations: 18     Fields:    Translation:Humans
    40. Zhang C, Zhang MX, Shen YH, Burks JK, Zhang Y, Wang J, LeMaire SA, Yoshimura K, Aoki H, Coselli JS, Wang XL. TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway. Arterioscler Thromb Vasc Biol. 2007 Aug; 27(8):1760-7. PMID: 17478756; PMCID: PMC2597036.
      Citations: 16     Fields:    Translation:HumansCells
    41. Wang XL, Zhang L, Youker K, Zhang MX, Wang J, LeMaire SA, Coselli JS, Shen YH. Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase. Diabetes. 2006 Aug; 55(8):2301-10. PMID: 16873694.
      Citations: 96     Fields:    Translation:HumansCells
    42. Wang X, LeMaire SA, Chen L, Shen YH, Gan Y, Bartsch H, Carter SA, Utama B, Ou H, Coselli JS, Wang XL. Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection. Circulation. 2006 Jul 04; 114(1 Suppl):I200-5. PMID: 16820572; PMCID: PMC2637375.
      Citations: 79     Fields:    Translation:Humans
    43. Chen L, Wang X, Carter SA, Shen YH, Bartsch HR, Thompson RW, Coselli JS, Wilcken DL, Wang XL, LeMaire SA. A single nucleotide polymorphism in the matrix metalloproteinase 9 gene (-8202A/G) is associated with thoracic aortic aneurysms and thoracic aortic dissection. J Thorac Cardiovasc Surg. 2006 May; 131(5):1045-52. PMID: 16678588; PMCID: PMC2604130.
      Citations: 20     Fields:    Translation:Humans
    44. Wang J, Shen YH, Utama B, Wang J, LeMaire SA, Coselli JS, Vercellotti GM, Wang XL. HCMV infection attenuates hydrogen peroxide induced endothelial apoptosis-- involvement of ERK pathway. FEBS Lett. 2006 May 15; 580(11):2779-87. PMID: 16650413.
      Citations: 11     Fields:    Translation:HumansCells
    45. Chen L, Shen YH, Wang X, Wang J, Gan Y, Chen N, Wang J, LeMaire SA, Coselli JS, Wang XL. Human prolyl-4-hydroxylase alpha(I) transcription is mediated by upstream stimulatory factors. J Biol Chem. 2006 Apr 21; 281(16):10849-55. PMID: 16488890; PMCID: PMC2819823.
      Citations: 25     Fields:    Translation:HumansCells
    46. Shen YH, Zhang L, Gan Y, Wang X, Wang J, LeMaire SA, Coselli JS, Wang XL. Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells. J Biol Chem. 2006 Mar 24; 281(12):7727-36. PMID: 16418168.
      Citations: 62     Fields:    Translation:HumansCells
    47. Shen YH, Zhang L, Utama B, Wang J, Gan Y, Wang X, Wang J, Chen L, Vercellotti GM, Coselli JS, Mehta JL, Wang XL. Human cytomegalovirus inhibits Akt-mediated eNOS activation through upregulating PTEN (phosphatase and tensin homolog deleted on chromosome 10). Cardiovasc Res. 2006 Feb 01; 69(2):502-11. PMID: 16316638.
      Citations: 26     Fields:    Translation:HumansCells
    48. Zhang MX, Ou H, Shen YH, Wang J, Wang J, Coselli J, Wang XL. Regulation of endothelial nitric oxide synthase by small RNA. Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47):16967-72. PMID: 16284254; PMCID: PMC1287968.
      Citations: 55     Fields:    Translation:HumansCells
    49. Ou H, Shen YH, Utama B, Wang J, Wang X, Coselli J, Wang XL. Effect of nuclear actin on endothelial nitric oxide synthase expression. Arterioscler Thromb Vasc Biol. 2005 Dec; 25(12):2509-14. PMID: 16210567; PMCID: PMC1382336.
      Citations: 21     Fields:    Translation:HumansCells
    50. Wang X, LeMaire SA, Chen L, Carter SA, Shen YH, Gan Y, Bartsch H, Wilks JA, Utama B, Ou H, Thompson RW, Coselli JS, Wang XL. Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection. Surgery. 2005 Aug; 138(2):352-9. PMID: 16153447.
      Citations: 27     Fields:    Translation:Humans
    51. Bakaeen FG, Reardon MJ, Coselli JS, Miller CC, Howell JF, Lawrie GM, Espada R, Ramchandani MK, Noon GP, Weilbaecher DG, DeBakey ME. Surgical outcome in 85 patients with primary cardiac tumors. Am J Surg. 2003 Dec; 186(6):641-7; discussion 647. PMID: 14672772.
      Citations: 44     Fields:    Translation:Humans
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