MICHAEL MANCINI

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pharmacology and Chemical Biology
    DivisionPharmacology


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    F32CA060435     (MANCINI, MICHAEL A)Oct 13, 1993
    NIH
    RB, RB-ASSOCIATED PROTEINS AND NUCLEAR ARCHITECTURE
    Role: Principal Investigator

    R01DK055622     (MANCINI, MICHAEL A)Jul 1, 1999 - May 31, 2010
    NIH
    Steroid Receptor Function and Nuclear Organization
    Role: Principal Investigator

    R03CA137777     (MANCINI, MICHAEL A)Sep 15, 2008 - Aug 31, 2012
    NIH
    High Content Analysis to Identify Biomarkers for Chemopreventive Drug Activity
    Role: Principal Investigator

    RC2ES018789     (WALKER, CHERYL L.)Sep 24, 2009 - Jul 31, 2013
    NIH
    Developmental Reprogramming of Prostate Carcinogenesis by BPA
    Role: Co-Principal Investigator

    S10RR027783     (MANCINI, MICHAEL A)May 1, 2011 - Apr 30, 2012
    NIH
    Nikon A1R Confocal Laser Scanning Microscope
    Role: Principal Investigator

    R01ES023206     (WALKER, CHERYL L)Sep 1, 2013 - May 31, 2018
    NIH
    Epigenetic Programmers Targeted During Developmental Reprogramming
    Role: Co-Principal Investigator

    S10OD020151     (MANCINI, MICHAEL A.)Mar 1, 2015 - Feb 29, 2016
    NIH
    OMX Super Resolution Microscope
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Stossi F, Singh PK, Mistry RM, Johnson HL, Dandekar RD, Mancini MG, Szafran AT, Rao AU, Mancini MA. Quality Control for Single Cell Imaging Analytics Using Endocrine Disruptor-Induced Changes in Estrogen Receptor Expression. Environ Health Perspect. 2022 02; 130(2):27008. PMID: 35167326.
      Citations:    Fields:    
    2. Rajan A, Weaver AM, Aloisio GM, Jelinski J, Johnson HL, Venable SF, McBride T, Aideyan L, Piedra FA, Ye X, Melicoff-Portillo E, Yerramilli MRK, Zeng XL, Mancini MA, Stossi F, Maresso AW, Kotkar SA, Estes MK, Blutt S, Avadhanula V, Piedra PA. The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pathogenesis and Evaluate Therapeutics. mBio. 2022 Feb 15; e0351121. PMID: 35164569.
      Citations: 1     Fields:    
    3. Bolt MJ, Singh P, Obkirchner CE, Powell RT, Mancini MG, Szafran AT, Stossi F, Mancini MA. Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-a. iScience. 2021 Nov 19; 24(11):103227. PMID: 34712924.
      Citations:    
    4. Chowdhury P, Perera D, Powell RT, Talley T, Tripathi DN, Park YS, Mancini MA, Davies P, Stephan C, Coarfa C, Dere R. Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells. Sci Rep. 2021 Aug 30; 11(1):17657. PMID: 34462545.
      Citations:    Fields:    
    5. Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, Singh PK, Bi M, Shi CJ, Jamal N, Li G, Mistry R, Jung SY, Tsai KL, Ferreon JC, Stossi F, Caflisch A, Liu Z, Mancini MA, Li W. Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation. Mol Cell. 2021 08 19; 81(16):3368-3385.e9. PMID: 34375583.
      Citations: 11     Fields:    Translation:HumansCells
    6. Ganesh HS, Beykal B, Szafran AT, Stossi F, Zhou L, Mancini MA, Pistikopoulos EN. Predicting the Estrogen Receptor Activity of Environmental Chemicals by Single-Cell Image Analysis and Data-driven Modeling. ESCAPE. 2021; 50:481-486. PMID: 34355221.
      Citations:    
    7. Chowdhury P, Perera D, Powell RT, Talley T, Tripathi DN, Park YS, Mancini MA, Davies P, Stephan C, Coarfa C, Dere R. Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells. Sci Rep. 2021 05 17; 11(1):10461. PMID: 34002003.
      Citations: 1     Fields:    Translation:HumansCells
    8. Liu H, Hu PW, Dubrulle J, Stossi F, Nikolai BC, Mancini MA, Rice AP. Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen. PLoS One. 2021; 16(4):e0244771. PMID: 33914760.
      Citations:    Fields:    Translation:HumansCells
    9. Holzer KJ, Vaughn MG, Fearn NE, Loux TM, Mancini MA. Age bias in the criteria for antisocial personality disorder. J Psychiatr Res. 2021 05; 137:444-451. PMID: 33780758.
      Citations: 2     Fields:    Translation:Humans
    10. Holzer KJ, Vaughn MG, Loux TM, Mancini MA, Fearn NE, Wallace CL. Prevalence and correlates of antisocial personality disorder in older adults. Aging Ment Health. 2022 01; 26(1):169-178. PMID: 33107330.
      Citations:    Fields:    Translation:Humans
    11. Mukherjee R, Beykal B, Szafran AT, Onel M, Stossi F, Mancini MG, Lloyd D, Wright FA, Zhou L, Mancini MA, Pistikopoulos EN. Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms. PLoS Comput Biol. 2020 09; 16(9):e1008191. PMID: 32970665.
      Citations: 2     Fields:    Translation:HumansCells
    12. Mistry RM, Singh PK, Mancini MG, Stossi F, Mancini MA. Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH. J Vis Exp. 2020 09 20; (163). PMID: 33016938.
      Citations: 1     Fields:    Translation:Cells
    13. Muscarella AM, Dai W, Mitchell PG, Zhang W, Wang H, Jia L, Stossi F, Mancini MA, Chiu W, Zhang XH. Unique cellular protrusions mediate breast cancer cell migration by tethering to osteogenic cells. NPJ Breast Cancer. 2020; 6:42. PMID: 32964116.
      Citations: 6     
    14. Yu X, Yi P, Hamilton RA, Shen H, Chen M, Foulds CE, Mancini MA, Ludtke SJ, Wang Z, O'Malley BW. Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Mol Cell. 2020 09 03; 79(5):812-823.e4. PMID: 32668201.
      Citations: 18     Fields:    Translation:HumansCells
    15. Yu W, Chen Y, Putluri N, Coarfa C, Robertson MJ, Putluri V, Stossi F, Dubrulle J, Mancini MA, Pang JC, Nguyen T, Baluya D, Myers JN, Lai SY, Sandulache VC. Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress. Cancers (Basel). 2020 Jun 24; 12(6). PMID: 32599707.
      Citations: 7     
    16. Stossi F, Mistry RM, Singh PK, Johnson HL, Mancini MG, Szafran AT, Mancini MA. Single-Cell Distribution Analysis of AR Levels by High-Throughput Microscopy in Cell Models: Application for Testing Endocrine-Disrupting Chemicals. SLAS Discov. 2020 08; 25(7):684-694. PMID: 32552291.
      Citations: 1     Fields:    Translation:Humans
    17. Szafran AT, Bolt MJ, Obkirchner CE, Mancini MG, Helsen C, Claessens F, Stossi F, Mancini MA. A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals. SLAS Discov. 2020 08; 25(7):695-708. PMID: 32392092.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    18. Nguyen TM, Kabotyanski EB, Reineke LC, Shao J, Xiong F, Lee JH, Dubrulle J, Johnson H, Stossi F, Tsoi PS, Choi KJ, Ellis AG, Zhao N, Cao J, Adewunmi O, Ferreon JC, Ferreon ACM, Neilson JR, Mancini MA, Chen X, Kim J, Ma L, Li W, Rosen JM. The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020 03 18; 48(5):2621-2642. PMID: 31863590.
      Citations: 24     Fields:    Translation:HumansCells
    19. Stossi F, Dandekar RD, Mancini MG, Gu G, Fuqua SAW, Nardone A, De Angelis C, Fu X, Schiff R, Bedford MT, Xu W, Johansson HE, Stephan CC, Mancini MA. Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity. Nucleic Acids Res. 2020 02 28; 48(4):1800-1810. PMID: 31930333.
      Citations: 5     Fields:    Translation:HumansCells
    20. Vossaert L, Wang Q, Salman R, McCombs AK, Patel V, Qu C, Mancini MA, Edwards DP, Malovannaya A, Liu P, Shaw CA, Levy B, Wapner RJ, Bi W, Breman AM, Van den Veyver IB, Beaudet AL. Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis. Am J Hum Genet. 2019 12 05; 105(6):1262-1273. PMID: 31785788.
      Citations: 15     Fields:    Translation:HumansCells
    21. Stossi F, Dandekar RD, Johnson H, Lavere P, Foulds CE, Mancini MG, Mancini MA. Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells. PLoS One. 2019; 14(11):e0224405. PMID: 31710612.
      Citations: 4     Fields:    Translation:HumansCells
    22. Mukherjee R, Onel M, Beykal B, Szafran AT, Stossi F, Mancini MA, Zhou L, Wright FA, Pistikopoulos EN. Development of the Texas A&M Superfund Research Program Computational Platform for Data Integration, Visualization, and Analysis. ESCAPE. 2019; 46:967-972. PMID: 31612156.
      Citations: 2     
    23. Kuthuru S, Szafran AT, Stossi F, Mancini MA, Rao A. Leveraging Image-Derived Phenotypic Measurements for Drug-Target Interaction Predictions. Cancer Inform. 2019; 18:1176935119856595. PMID: 31217689.
      Citations: 2     
    24. Di Bona M, Mancini MA, Mazza D, Vicidomini G, Diaspro A, Lanzanò L. Measuring Mobility in Chromatin by Intensity-Sorted FCS. Biophys J. 2019 03 19; 116(6):987-999. PMID: 30819566.
      Citations: 10     Fields:    Translation:HumansCells
    25. Xia J, Chiu LY, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali A, Matadamas Guzmán ML, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell. 2019 01 10; 176(1-2):127-143.e24. PMID: 30633903.
      Citations: 33     Fields:    Translation:HumansCells
    26. Chowdhury P, Powell RT, Stephan C, Uray IP, Talley T, Karki M, Tripathi DN, Park YS, Mancini MA, Davies P, Dere R. Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells. J Cell Sci. 2018 12 14; 131(24). PMID: 30518623.
      Citations: 2     Fields:    Translation:HumansCells
    27. Cheng D, Vemulapalli V, Lu Y, Shen J, Aoyagi S, Fry CJ, Yang Y, Foulds CE, Stossi F, Treviño LS, Mancini MA, O'Malley BW, Walker CL, Boyer TG, Bedford MT. CARM1 methylates MED12 to regulate its RNA-binding ability. Life Sci Alliance. 2018 Oct; 1(5):e201800117. PMID: 30456381.
      Citations: 19     Fields:    
    28. Szwarc MM, Kommagani R, Putluri V, Dubrulle J, Stossi F, Mancini MA, Coarfa C, Lanz RB, Putluri N, DeMayo FJ, Lydon JP, O'Malley BW. Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134. PMID: 30177747.
      Citations: 1     Fields:    Translation:HumansCells
    29. Szafran AT, Stossi F, Mancini MG, Walker CL, Mancini MA. Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis. PLoS One. 2017; 12(7):e0180141. PMID: 28704378.
      Citations: 11     Fields:    Translation:HumansCells
    30. Wang H, Tian L, Goldstein A, Liu J, Lo HC, Sheng K, Welte T, Wong STC, Gugala Z, Stossi F, Zong C, Li Z, Mancini MA, Zhang XH. Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies. Nat Commun. 2017 04 21; 8:15045. PMID: 28429794.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    31. Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, Sheng K, Dobrolecki LE, Zhang X, Putluri N, Phung TL, Mani SA, Stossi F, Sreekumar A, Mancini MA, Decker WK, Zong C, Lewis MT, Zhang XH. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017 04 13; 544(7649):250-254. PMID: 28371798.
      Citations: 223     Fields:    Translation:HumansAnimalsCells
    32. Aagaard KM, Lahon A, Suter MA, Arya RP, Seferovic MD, Vogt MB, Hu M, Stossi F, Mancini MA, Harris RA, Kahr M, Eppes C, Rac M, Belfort MA, Park CS, Lacorazza D, Rico-Hesse R. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017 01 27; 7:41389. PMID: 28128342.
      Citations: 54     Fields:    Translation:HumansCells
    33. Szafran AT, Stephan C, Bolt M, Mancini MG, Marcelli M, Mancini MA. High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth. Prostate. 2017 01; 77(1):82-93. PMID: 27699828.
      Citations: 10     Fields:    Translation:HumansCells
    34. Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B. The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Prostate. 2016 10; 76(14):1271-84. PMID: 27272765.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    35. Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar A. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016 05 19; 7:11612. PMID: 27194471.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    36. Stossi F, Dandekar RD, Bolt MJ, Newberg JY, Mancini MG, Kaushik AK, Putluri V, Sreekumar A, Mancini MA. High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator. Oncotarget. 2016 Mar 29; 7(13):16962-74. PMID: 26918604.
      Citations: 8     Fields:    Translation:HumansCells
    37. Sun H, Mediwala SN, Szafran AT, Mancini MA, Marcelli M. CUDC-101, a Novel Inhibitor of Full-Length Androgen Receptor (flAR) and Androgen Receptor Variant 7 (AR-V7) Activity: Mechanism of Action and In Vivo Efficacy. Horm Cancer. 2016 06; 7(3):196-210. PMID: 26957440.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    38. Treviño LS, Bolt MJ, Grimm SL, Edwards DP, Mancini MA, Weigel NL. Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK. Mol Endocrinol. 2016 Feb; 30(2):158-72. PMID: 26652902.
      Citations: 5     Fields:    Translation:HumansCells
    39. Szafran AT, Mancini MG, Nickerson JA, Edwards DP, Mancini MA. Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns. Methods. 2016 Mar 01; 96:75-84. PMID: 26521976.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    40. Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10; 28(2):240-52. PMID: 26267537.
      Citations: 45     Fields:    Translation:HumansCells
    41. Hartig SM, Bader DA, Abadie KV, Motamed M, Hamilton MP, Long W, York B, Mueller M, Wagner M, Trauner M, Chan L, Bajaj M, Moore DD, Mancini MA, McGuire SE. Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes. Mol Endocrinol. 2015 Sep; 29(9):1320-33. PMID: 26192107.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    42. Large MJ, Wetendorf M, Lanz RB, Hartig SM, Creighton CJ, Mancini MA, Kovanci E, Lee KF, Threadgill DW, Lydon JP, Jeong JW, DeMayo FJ. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451. PMID: 24945252.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    43. Stossi F, Bolt MJ, Ashcroft FJ, Lamerdin JE, Melnick JS, Powell RT, Dandekar RD, Mancini MG, Walker CL, Westwick JK, Mancini MA. Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays. Chem Biol. 2014 Jun 19; 21(6):743-53. PMID: 24856822.
      Citations: 26     Fields:    Translation:HumansCells
    44. Lee J, Tiwari A, Shum V, Mills GB, Mancini MA, Igoshin OA, Balázsi G. Unraveling the regulatory connections between two controllers of breast cancer cell fate. Nucleic Acids Res. 2014 Jun; 42(11):6839-49. PMID: 24792166.
      Citations: 7     Fields:    Translation:HumansCells
    45. Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. Oncogene. 2015 Mar 12; 34(11):1341-53. PMID: 24681959.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    46. Bolt MJ, Stossi F, Callison AM, Mancini MG, Dandekar R, Mancini MA. Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-a protein levels and activity. Oncogene. 2015 Jan 08; 34(2):154-64. PMID: 24441042.
      Citations: 11     Fields:    Translation:HumansCells
    47. Szafran AT, Mancini MA. The myImageAnalysis project: a web-based application for high-content screening. Assay Drug Dev Technol. 2014 Jan-Feb; 12(1):87-99. PMID: 24547743.
      Citations: 16     Fields:    
    48. Bolt MJ, Stossi F, Newberg JY, Orjalo A, Johansson HE, Mancini MA. Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses. Nucleic Acids Res. 2013 Apr; 41(7):4036-48. PMID: 23444138.
      Citations: 30     Fields:    Translation:HumansCells
    49. McDonough PM, Maciejewski-Lenoir D, Hartig SM, Hanna RA, Whittaker R, Heisel A, Nicoll JB, Buehrer BM, Christensen K, Mancini MG, Mancini MA, Edwards DP, Price JH. Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis. PLoS One. 2013; 8(2):e55511. PMID: 23405163.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    50. Hartig SM, He B, Newberg JY, Ochsner SA, Loose DS, Lanz RB, McKenna NJ, Buehrer BM, McGuire SE, Marcelli M, Mancini MA. Feed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes. Chem Biol. 2012 Sep 21; 19(9):1126-41. PMID: 22999881.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    51. Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor a target gene activation. Proc Natl Acad Sci U S A. 2012 Aug 14; 109(33):13331-6. PMID: 22853951.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    52. Mediwala SN, Sun H, Szafran AT, Hartig SM, Sonpavde G, Hayes TG, Thiagarajan P, Mancini MA, Marcelli M. The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way. Prostate. 2013 Feb 15; 73(3):267-77. PMID: 22821817.
      Citations: 23     Fields:    Translation:HumansCells
    53. Zakharov MN, Bhasin S, Szafran AT, Mancini MA, Jasuja R. Numerical framework to model temporally resolved multi-stage dynamic systems. Comput Methods Programs Biomed. 2012 Nov; 108(2):750-9. PMID: 22727632.
      Citations:    Fields:    Translation:HumansCells
    54. Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar; 32(6):1099-111. PMID: 22269949.
      Citations: 68     Fields:    Translation:AnimalsCells
    55. Slattery SD, Newberg JY, Szafran AT, Hall RM, Brinkley BR, Mancini MA. A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Technol. 2012 Apr; 10(2):161-78. PMID: 22084958.
      Citations: 5     Fields:    Translation:HumansCells
    56. Uray IP, Rodenberg JM, Bissonnette RP, Brown PH, Mancini MA. Cancer-preventive rexinoid modulates neutral lipid contents of mammary epithelial cells through a peroxisome proliferator-activated receptor ?-dependent mechanism. Mol Pharmacol. 2012 Feb; 81(2):228-38. PMID: 22053058.
      Citations: 7     Fields:    Translation:HumansCells
    57. Ashcroft FJ, Newberg JY, Jones ED, Mikic I, Mancini MA. High content imaging-based assay to classify estrogen receptor-a ligands based on defined mechanistic outcomes. Gene. 2011 May 15; 477(1-2):42-52. PMID: 21256200.
      Citations: 19     Fields:    Translation:HumansCells
    58. Hartig SM, He B, Long W, Buehrer BM, Mancini MA. Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis. J Cell Biol. 2011 Jan 10; 192(1):55-67. PMID: 21220509.
      Citations: 22     Fields:    Translation:HumansCells
    59. Hartig SM, Newberg JY, Bolt MJ, Szafran AT, Marcelli M, Mancini MA. Automated microscopy and image analysis for androgen receptor function. Methods Mol Biol. 2011; 776:313-31. PMID: 21796534.
      Citations: 10     Fields:    Translation:HumansCells
    60. Szafran AT, Sun H, Hartig S, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. Adv Exp Med Biol. 2011; 707:63-5. PMID: 21691957.
      Citations: 2     Fields:    Translation:HumansCells
    61. García-Becerra R, Berno V, Ordaz-Rosado D, Sharp ZD, Cooney AJ, Mancini MA, Larrea F. Ligand-induced large-scale chromatin dynamics as a biosensor for the detection of estrogen receptor subtype selective ligands. Gene. 2010 Jun 15; 458(1-2):37-44. PMID: 20347019.
      Citations: 4     Fields:    Translation:HumansCells
    62. Zwart W, de Leeuw R, Rondaij M, Neefjes J, Mancini MA, Michalides R. The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen. J Cell Sci. 2010 Apr 15; 123(Pt 8):1253-61. PMID: 20332105.
      Citations: 35     Fields:    Translation:HumansCells
    63. Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32. PMID: 20159552.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    64. Narayanan R, Yepuru M, Szafran AT, Szwarc M, Bohl CE, Young NL, Miller DD, Mancini MA, Dalton JT. Discovery and mechanistic characterization of a novel selective nuclear androgen receptor exporter for the treatment of prostate cancer. Cancer Res. 2010 Jan 15; 70(2):842-51. PMID: 20068182.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    65. Szafran AT, Hartig S, Sun H, Uray IP, Szwarc M, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. PLoS One. 2009 Dec 09; 4(12):e8179. PMID: 20011049.
      Citations: 11     Fields:    Translation:HumansCells
    66. Slattery SD, Mancini MA, Brinkley BR, Hall RM. Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle. 2009 Sep 15; 8(18):2984-94. PMID: 19713763.
      Citations: 37     Fields:    Translation:HumansCells
    67. Zwart W, Rondaij M, Jalink K, Sharp ZD, Mancini MA, Neefjes J, Michalides R. Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1. Mol Endocrinol. 2009 Sep; 23(9):1335-45. PMID: 19477949.
      Citations: 16     Fields:    Translation:HumansCells
    68. Giordano C, Cui Y, Barone I, Ando S, Mancini MA, Berno V, Fuqua SA. Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305. Breast Cancer Res Treat. 2010 Jan; 119(1):71-85. PMID: 19205871.
      Citations: 28     Fields:    Translation:HumansCells
    69. Szafran AT, Szwarc M, Marcelli M, Mancini MA. Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One. 2008; 3(11):e3605. PMID: 18978937.
      Citations: 32     Fields:    Translation:HumansCells
    70. Berno V, Amazit L, Hinojos C, Zhong J, Mancini MG, Sharp ZD, Mancini MA. Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription. PLoS One. 2008 May 28; 3(5):e2286. PMID: 18509470.
      Citations: 18     Fields:    Translation:HumansCells
    71. Huang Y, Qiu J, Dong S, Redell MS, Poli V, Mancini MA, Tweardy DJ. Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end. J Biol Chem. 2007 Nov 30; 282(48):34958-67. PMID: 17855361.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    72. Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol. 2007 Oct; 27(19):6913-32. PMID: 17646391.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    73. Prigozhina NL, Zhong L, Hunter EA, Mikic I, Callaway S, Roop DR, Mancini MA, Zacharias DA, Price JH, McDonough PM. Plasma membrane assays and three-compartment image cytometry for high content screening. Assay Drug Dev Technol. 2007 Feb; 5(1):29-48. PMID: 17355198.
      Citations: 7     Fields:    Translation:HumansCells
    74. Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP. The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol. 2007 Feb; 21(2):359-75. PMID: 17138644.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    75. Sharp ZD, Mancini MG, Hinojos CA, Dai F, Berno V, Szafran AT, Smith KP, Lele TP, Lele TT, Ingber DE, Mancini MA. Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci. 2006 Oct 01; 119(Pt 19):4101-16. PMID: 16968748.
      Citations: 62     Fields:    Translation:HumansCells
    76. Marcelli M, Stenoien DL, Szafran AT, Simeoni S, Agoulnik IU, Weigel NL, Moran T, Mikic I, Price JH, Mancini MA. Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility. J Cell Biochem. 2006 Jul 01; 98(4):770-88. PMID: 16440331.
      Citations: 42     Fields:    Translation:HumansCells
    77. Berno V, Hinojos CA, Amazit L, Szafran AT, Mancini MA. High-resolution, high-throughput microscopy analyses of nuclear receptor and coregulator function. Methods Enzymol. 2006; 414:188-210. PMID: 17110193.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    78. Ho TH, Savkur RS, Poulos MG, Mancini MA, Swanson MS, Cooper TA. Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. J Cell Sci. 2005 Jul 01; 118(Pt 13):2923-33. PMID: 15961406.
      Citations: 99     Fields:    Translation:HumansCells
    79. Hinojos CA, Sharp ZD, Mancini MA. Molecular dynamics and nuclear receptor function. Trends Endocrinol Metab. 2005 Jan-Feb; 16(1):12-8. PMID: 15620544.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    80. Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M. Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence. Cancer Res. 2004 Oct 01; 64(19):7156-68. PMID: 15466214.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    81. Sharp ZD, Stenoien DL, Mancini MG, Ouspenski II, Mancini MA. Inactivating Pit-1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response. J Cell Biochem. 2004 Jul 01; 92(4):664-78. PMID: 15211565.
      Citations: 3     Fields:    Translation:HumansCells
    82. Dong S, Stenoien DL, Qiu J, Mancini MA, Tweardy DJ. Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha. Mol Cell Biol. 2004 May; 24(10):4465-75. PMID: 15121864.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    83. Contreras A, Hale TK, Stenoien DL, Rosen JM, Mancini MA, Herrera RE. The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol. 2003 Dec; 23(23):8626-36. PMID: 14612406.
      Citations: 66     Fields:    Translation:HumansCells
    84. Stenoien DL, Sen S, Mancini MA, Brinkley BR. Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton. 2003 Jun; 55(2):134-46. PMID: 12740874.
      Citations: 33     Fields:    Translation:HumansCells
    85. Dong S, Qiu J, Stenoien DL, Brinkley WR, Mancini MA, Tweardy DJ. Essential role for the dimerization domain of NuMA-RARalpha in its oncogenic activities and localization to NuMA sites within the nucleus. Oncogene. 2003 Feb 13; 22(6):858-68. PMID: 12584566.
      Citations: 4     Fields:    Translation:AnimalsCells
    86. Stenoien DL, Mielke M, Mancini MA. Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components. Nat Cell Biol. 2002 Oct; 4(10):806-10. PMID: 12360291.
      Citations: 45     Fields:    Translation:HumansCells
    87. Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS. Alteration of large-scale chromatin structure by estrogen receptor. Mol Cell Biol. 2002 May; 22(10):3437-49. PMID: 11971975.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    88. Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Mol Cell Biol. 2001 Jul; 21(13):4404-12. PMID: 11390668.
      Citations: 53     Fields:    Translation:AnimalsCells
    89. Herrmann CH, Mancini MA. The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions. J Cell Sci. 2001 Apr; 114(Pt 8):1491-503. PMID: 11282025.
      Citations: 59     Fields:    Translation:HumansCells
    90. Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MA. FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol. 2001 Jan; 3(1):15-23. PMID: 11146621.
      Citations: 122     Fields:    Translation:HumansCells
    91. Stenoien DL, Mancini MG, Patel K, Allegretto EA, Smith CL, Mancini MA. Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1. Mol Endocrinol. 2000 Apr; 14(4):518-34. PMID: 10770489.
      Citations: 58     Fields:    Translation:HumansCells
    92. Prakash SK, Paylor R, Jenna S, Lamarche-Vane N, Armstrong DL, Xu B, Mancini MA, Zoghbi HY. Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA. Hum Mol Genet. 2000 Mar 01; 9(4):477-88. PMID: 10699171.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    93. Simeoni S, Mancini MA, Stenoien DL, Marcelli M, Weigel NL, Zanisi M, Martini L, Poletti A. Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract. Hum Mol Genet. 2000 Jan 01; 9(1):133-44. PMID: 10587588.
      Citations: 45     Fields:    Translation:AnimalsCells
    94. Stenoien DL, Simeoni S, Sharp ZD, Mancini MA. Subnuclear dynamics and transcription factor function. J Cell Biochem Suppl. 2000; Suppl 35:99-106. PMID: 11389538.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    95. Van Hooser AA, Mancini MA, Allis CD, Sullivan KF, Brinkley BR. The mammalian centromere: structural domains and the attenuation of chromatin modeling. FASEB J. 1999 Dec; 13 Suppl 2:S216-20. PMID: 10619130.
      Citations: 14     Fields:    Translation:AnimalsCells
    96. Kazansky AV, Kabotyanski EB, Wyszomierski SL, Mancini MA, Rosen JM. Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A. J Biol Chem. 1999 Aug 06; 274(32):22484-92. PMID: 10428824.
      Citations: 28     Fields:    Translation:Cells
    97. Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA. Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet. 1999 May; 8(5):731-41. PMID: 10196362.
      Citations: 127     Fields:    Translation:HumansCells
    98. Mancini MG, Liu B, Sharp ZD, Mancini MA. Subnuclear partitioning and functional regulation of the Pit-1 transcription factor. J Cell Biochem. 1999 Mar 01; 72(3):322-38. PMID: 10022514.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    99. Van Hooser A, Goodrich DW, Allis CD, Brinkley BR, Mancini MA. Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. J Cell Sci. 1998 Dec; 111 ( Pt 23):3497-506. PMID: 9811564.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    100. Stenoien D, Sharp ZD, Smith CL, Mancini MA. Functional subnuclear partitioning of transcription factors. J Cell Biochem. 1998 Aug 01; 70(2):213-21. PMID: 9671227.
      Citations: 8     Fields:    Translation:HumansCells
    101. Cummings CJ, Mancini MA, Antalffy B, DeFranco DB, Orr HT, Zoghbi HY. Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet. 1998 Jun; 19(2):148-54. PMID: 9620770.
      Citations: 250     Fields:    Translation:HumansAnimalsCells
    102. Hendzel MJ, Wei Y, Mancini MA, Van Hooser A, Ranalli T, Brinkley BR, Bazett-Jones DP, Allis CD. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma. 1997 Nov; 106(6):348-60. PMID: 9362543.
      Citations: 732     Fields:    Translation:AnimalsCells
    103. Mancini MA, He D, Ouspenski II, Brinkley BR. Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle. J Cell Biochem. 1996 Aug; 62(2):158-64. PMID: 8844395.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    104. Chatterjee B, Song CS, Jung MH, Chen S, Walter CA, Herbert DC, Weaker FJ, Mancini MA, Roy AK. Targeted overexpression of androgen receptor with a liver-specific promoter in transgenic mice. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):728-33. PMID: 8570624.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    105. Zhu X, Mancini MA, Chang KH, Liu CY, Chen CF, Shan B, Jones D, Yang-Feng TL, Lee WH. Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression. Mol Cell Biol. 1995 Sep; 15(9):5017-29. PMID: 7651420.
      Citations: 51     Fields:    Translation:HumansCells
    106. Zhu X, Chang KH, He D, Mancini MA, Brinkley WR, Lee WH. The C terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization. J Biol Chem. 1995 Aug 18; 270(33):19545-50. PMID: 7642639.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    107. Durfee T, Mancini MA, Jones D, Elledge SJ, Lee WH. The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing. J Cell Biol. 1994 Nov; 127(3):609-22. PMID: 7525595.
      Citations: 53     Fields:    Translation:AnimalsCells
    108. Mancini MA, Shan B, Nickerson JA, Penman S, Lee WH. The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):418-22. PMID: 8278403.
      Citations: 70     Fields:    Translation:HumansCells
    109. Magnuson VL, Young M, Schattenberg DG, Mancini MA, Chen DL, Steffensen B, Klebe RJ. The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors. J Biol Chem. 1991 Aug 05; 266(22):14654-62. PMID: 1713586.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    110. Mancini MA, Chatterjee B, Roy AK. Age-dependent reversal of the lobular distribution of androgen-inducible alpha 2u globulin and androgen-repressible SMP-2 in rat liver. J Histochem Cytochem. 1991 Apr; 39(4):401-5. PMID: 1706374.
      Citations: 1     Fields:    Translation:Animals
    111. Mancini MA, Kennedy A, Frank RN, Trese MT, Hartzer M, Hukku B, Lin LR. A cell line derived from non-neoplastic human neuroretinal cells. Invest Ophthalmol Vis Sci. 1989 Mar; 30(3):499-508. PMID: 2925321.
      Citations:    Fields:    Translation:HumansCells
    112. Weber ML, Mancini MA, Frank RN. Retinovitreal neovascularization in the Royal College of Surgeons rat. Curr Eye Res. 1989 Jan; 8(1):61-74. PMID: 2468452.
      Citations: 3     Fields:    Translation:Animals
    113. Das A, Frank RN, Weber ML, Kennedy A, Reidy CA, Mancini MA. ATP causes retinal pericytes to contract in vitro. Exp Eye Res. 1988 Mar; 46(3):349-62. PMID: 3258246.
      Citations: 16     Fields:    Translation:AnimalsCells
    114. Frank RN, Dutta S, Mancini MA. Pericyte coverage is greater in the retinal than in the cerebral capillaries of the rat. Invest Ophthalmol Vis Sci. 1987 Jul; 28(7):1086-91. PMID: 3596989.
      Citations: 36     Fields:    Translation:AnimalsCells
    115. Kennedy A, Frank RN, Mancini MA. In vitro production of glycosaminoglycans by retinal microvessel cells and lens epithelium. Invest Ophthalmol Vis Sci. 1986 May; 27(5):746-54. PMID: 3700024.
      Citations: 2     Fields:    Translation:Animals
    116. Frank RN, Mancini MA. Presumed retinovitreal neovascularization in dystrophic retinas of spontaneously hypertensive rats. Invest Ophthalmol Vis Sci. 1986 Mar; 27(3):346-55. PMID: 2419273.
      Citations: 1     Fields:    Translation:Animals
    117. Mancini MA, Frank RN, Keirn RJ, Kennedy A, Khoury JK. Does the retinal pigment epithelium polarize the choriocapillaris? Invest Ophthalmol Vis Sci. 1986 Mar; 27(3):336-45. PMID: 3949463.
      Citations: 7     Fields:    Translation:AnimalsCells
    118. Kennedy A, Frank RN, Mancini MA, Lande M. Collagens of the retinal microvascular basement membrane and of retinal microvascular cells in vitro. Exp Eye Res. 1986 Feb; 42(2):177-99. PMID: 3516712.
      Citations: 4     Fields:    Translation:AnimalsCells
    119. Frank RN, Keirn RJ, Keirn GV, Mancini MA, Khoury JK. Retinal dystrophy: development retarded by galactose feeding in spontaneously hypertensive rats. Science. 1986 Jan 24; 231(4736):376-8. PMID: 3941900.
      Citations:    Fields:    Translation:HumansAnimals
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