Binding Sites, Antibody

"Binding Sites, Antibody" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Local surface sites on antibodies which react with antigen determinant sites on antigens (EPITOPES.) They are formed from parts of the variable regions of FAB FRAGMENTS.

Descriptor ID	D001666
MeSH Number(s)	G02.111.570.060.425.079 G02.111.570.120.408 G12.122.232 G12.125
Concept/Terms	Binding Sites, Antibody Binding Sites, Antibody Antibody Binding Site Binding Site, Antibody Paratopes Paratope Antibody Binding Sites

Below are MeSH descriptors whose meaning is more general than "Binding Sites, Antibody".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Amino Acid Sequence [G02.111.570.060]
Immunoglobulin Variable Region [G02.111.570.060.425]
Binding Sites, Antibody [G02.111.570.060.425.079]
Binding Sites [G02.111.570.120]
Binding Sites, Antibody [G02.111.570.120.408]
Immune System Phenomena [G12]
Antigen-Antibody Reactions [G12.122]
Binding Sites, Antibody [G12.122.232]
Binding Sites, Antibody [G12.125]

Below are MeSH descriptors whose meaning is related to "Binding Sites, Antibody".

Below are MeSH descriptors whose meaning is more specific than "Binding Sites, Antibody".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Binding Sites, Antibody" by people in this website by year, and whether "Binding Sites, Antibody" was a major or minor topic of these publications.

Bar chart showing 51 publications over 27 distinct years, with a maximum of 7 publications in 1992

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	7	7
1994	0	1	1
1995	0	1	1
1996	0	1	1
1997	0	1	1
1998	0	1	1
2000	0	2	2
2001	0	1	1
2002	0	3	3
2003	1	0	1
2004	0	1	1
2005	0	1	1
2007	1	3	4
2008	0	2	2
2009	1	4	5
2011	1	1	2
2012	0	1	1
2013	0	3	3
2014	0	1	1
2015	0	2	2
2016	0	1	1
2017	1	2	3
2018	0	1	1
2019	0	1	1
2020	0	2	2
2021	0	1	1
2022	0	1	1

Below are the most recent publications written about "Binding Sites, Antibody" by people in Profiles.

Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, Mucker EM, Fouch ME, Davidson E, Doranz BJ, Kailasan S, Aman MJ, Li H, Hooper JW, Saphire EO, Crowe JE, Liu Q, Axelrod F, Sato AK. Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022 Jan-Dec; 14(1):2002236.

View in: PubMed
Tahir S, Bourquard T, Musnier A, Jullian Y, Corde Y, Omahdi Z, Mathias L, Reiter E, Crépieux P, Bruneau G, Poupon A. Accurate determination of epitope for antibodies with unknown 3D structures. MAbs. 2021 Jan-Dec; 13(1):1961349.

View in: PubMed
Huang W, Soeung V, Boragine DM, Hu L, Prasad BVV, Estes MK, Atmar RL, Palzkill T. High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing. J Virol. 2020 12 09; 95(1).

View in: PubMed
Sevy AM, Gilchuk IM, Brown BP, Bozhanova NG, Nargi R, Jensen M, Meiler J, Crowe JE. Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants. Structure. 2020 10 06; 28(10):1114-1123.e4.

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Bellows S, Jankovic J. Immunogenicity Associated with Botulinum Toxin Treatment. Toxins (Basel). 2019 08 26; 11(9).

View in: PubMed
Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE. Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. PLoS Pathog. 2018 02; 14(2):e1006837.

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Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure. 2017 12 05; 25(12):1820-1828.e2.

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Lim XX, Chandramohan A, Lim XE, Crowe JE, Lok SM, Anand GS. Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface. Structure. 2017 09 05; 25(9):1391-1402.e3.

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Hurwitz AM, Huang W, Kou B, Estes MK, Atmar RL, Palzkill T. Identification and Characterization of Single-Chain Antibodies that Specifically Bind GI Noroviruses. PLoS One. 2017; 12(1):e0170162.

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Thornburg NJ, Zhang H, Bangaru S, Sapparapu G, Kose N, Lampley RM, Bombardi RG, Yu Y, Graham S, Branchizio A, Yoder SM, Rock MT, Creech CB, Edwards KM, Lee D, Li S, Wilson IA, García-Sastre A, Albrecht RA, Crowe JE. H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. J Clin Invest. 2016 Apr 01; 126(4):1482-94.

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