"Binding Sites, Antibody" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Local surface sites on antibodies which react with antigen determinant sites on antigens (EPITOPES.) They are formed from parts of the variable regions of FAB FRAGMENTS.
| Descriptor ID |
D001666
|
| MeSH Number(s) |
G02.111.570.060.425.079 G02.111.570.120.408 G12.122.232 G12.125
|
| Concept/Terms |
Binding Sites, Antibody- Binding Sites, Antibody
- Antibody Binding Site
- Binding Site, Antibody
- Paratopes
- Paratope
- Antibody Binding Sites
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites, Antibody".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites, Antibody".
This graph shows the total number of publications written about "Binding Sites, Antibody" by people in this website by year, and whether "Binding Sites, Antibody" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 3 | 3 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Binding Sites, Antibody" by people in Profiles.
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Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022 Jan-Dec; 14(1):2002236.
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Accurate determination of epitope for antibodies with unknown 3D structures. MAbs. 2021 Jan-Dec; 13(1):1961349.
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High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing. J Virol. 2020 12 09; 95(1).
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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. Cell Rep. 2020 10 27; 33(4):108322.
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Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants. Structure. 2020 10 06; 28(10):1114-1123.e4.
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Immunogenicity Associated with Botulinum Toxin Treatment. Toxins (Basel). 2019 08 26; 11(9).
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Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. PLoS Pathog. 2018 02; 14(2):e1006837.
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Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure. 2017 12 05; 25(12):1820-1828.e2.
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Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens. Clin Immunol. 2018 02; 187:37-45.
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Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface. Structure. 2017 09 05; 25(9):1391-1402.e3.