"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 3 | 5 |
| 1996 | 4 | 2 | 6 |
| 1997 | 2 | 4 | 6 |
| 1998 | 2 | 4 | 6 |
| 1999 | 4 | 4 | 8 |
| 2000 | 3 | 10 | 13 |
| 2001 | 3 | 8 | 11 |
| 2002 | 3 | 10 | 13 |
| 2003 | 1 | 8 | 9 |
| 2004 | 5 | 10 | 15 |
| 2005 | 5 | 13 | 18 |
| 2006 | 1 | 14 | 15 |
| 2007 | 6 | 17 | 23 |
| 2008 | 1 | 11 | 12 |
| 2009 | 3 | 12 | 15 |
| 2010 | 4 | 10 | 14 |
| 2011 | 7 | 18 | 25 |
| 2012 | 2 | 6 | 8 |
| 2013 | 3 | 9 | 12 |
| 2014 | 1 | 13 | 14 |
| 2015 | 4 | 7 | 11 |
| 2016 | 1 | 12 | 13 |
| 2017 | 2 | 14 | 16 |
| 2018 | 2 | 12 | 14 |
| 2019 | 3 | 12 | 15 |
| 2020 | 3 | 10 | 13 |
| 2021 | 4 | 5 | 9 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 4 | 4 |
| 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Dendritic cell expression of MyD88 is required for rotavirus-induced B cell activation. J Virol. 2025 May 20; 99(5):e0065325.
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A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function. Cancer Res Commun. 2025 03 01; 5(3):527-548.
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Gene editing of CD3 epsilon to redirect regulatory T?cells for adoptive T?cell transfer. Mol Ther. 2025 Mar 05; 33(3):997-1013.
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HIF1a-regulated glycolysis promotes activation-induced cell death and IFN-? induction in hypoxic T cells. Nat Commun. 2024 10 30; 15(1):9394.
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Histone lactylation drives CD8+ T cell metabolism and function. Nat Immunol. 2024 Nov; 25(11):2140-2151.
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NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs. Cancer Immunol Res. 2024 Oct 01; 12(10):1421-1437.
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TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions. Nat Commun. 2024 Aug 14; 15(1):6971.
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6-Formylindolo[3,2-b]carbazole, a potent ligand for the aryl hydrocarbon receptor, attenuates concanavalin-induced hepatitis by limiting T-cell activation and infiltration of proinflammatory CD11b+ Kupffer cells. J Leukoc Biol. 2024 05 29; 115(6):1070-1083.
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Consensus recommendations on the management of toxicity associated with CD3?CD20 bispecific antibody therapy. Blood. 2024 04 18; 143(16):1565-1575.
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BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1. J Immunother Cancer. 2024 Mar 14; 12(3).