"Immunoglobulin Idiotypes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
| Descriptor ID |
D007130
|
| MeSH Number(s) |
D12.644.541.500.745 D12.776.124.486.485.680.745 D12.776.124.790.651.680.745 D12.776.377.715.548.680.745 D23.050.550.750 G02.111.570.060.425.580 G12.500.450
|
| Concept/Terms |
Immunoglobulin Idiotypes- Immunoglobulin Idiotypes
- Idiotype, Immunoglobulin
- Immunoglobulin Idiotype
- Idiotypes, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Idiotypes".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Idiotypes".
This graph shows the total number of publications written about "Immunoglobulin Idiotypes" by people in this website by year, and whether "Immunoglobulin Idiotypes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Immunoglobulin Idiotypes" by people in Profiles.
-
Antigenic Fingerprinting of Respiratory Syncytial Virus (RSV)-A-Infected Hematopoietic Cell Transplant Recipients Reveals Importance of Mucosal Anti-RSV G Antibodies in Control of RSV Infection in Humans. J Infect Dis. 2020 02 03; 221(4):636-646.
-
Active idiotypic vaccination versus control immunotherapy for follicular lymphoma. J Clin Oncol. 2014 Jun 10; 32(17):1797-803.
-
Optimizing dendritic cell vaccine for immunotherapy in multiple myeloma: tumour lysates are more potent tumour antigens than idiotype protein to promote anti-tumour immunity. Clin Exp Immunol. 2012 Nov; 170(2):167-77.
-
Neoantigen and tumor antigen-specific immunity transferred from immunized donors is detectable early after allogeneic transplantation in myeloma patients. Bone Marrow Transplant. 2013 Feb; 48(2):269-77.
-
CpG or IFN-a are more potent adjuvants than GM-CSF to promote anti-tumor immunity following idiotype vaccine in multiple myeloma. Cancer Immunol Immunother. 2012 Apr; 61(4):561-71.
-
Targeting human B-cell malignancies through Ig light chain-specific cytotoxic T lymphocytes. Clin Cancer Res. 2011 Sep 15; 17(18):5945-52.
-
Qualitative change in antibody responses of human immunodeficiency virus-infected individuals to pneumococcal capsular polysaccharide vaccination associated with highly active antiretroviral therapy. J Infect Dis. 2003 Mar 01; 187(5):758-68.
-
Preferential recognition of TCR hypervariable regions by human anti-idiotypic T cells induced by T cell vaccination. J Immunol. 2000 Apr 15; 164(8):4011-7.
-
Molecular and idiotypic analyses of the antibody response to Cryptococcus neoformans glucuronoxylomannan-protein conjugate vaccine in autoimmune and nonautoimmune mice. Infect Immun. 1999 Sep; 67(9):4469-76.
-
Cytotoxic T lymphocytes specific for self tumor immunoglobulin express T cell receptor delta chain. J Exp Med. 1989 May 01; 169(5):1557-64.