"Vinculin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.
| Descriptor ID |
D016596
|
| MeSH Number(s) |
D12.776.220.990
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vinculin".
Below are MeSH descriptors whose meaning is more specific than "Vinculin".
This graph shows the total number of publications written about "Vinculin" by people in this website by year, and whether "Vinculin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vinculin" by people in Profiles.
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VIncristine, irinotecan, and temozolomide in children and adolescents with relapsed rhabdomyosarcoma. Pediatr Blood Cancer. 2018 Jan; 65(1).
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The maternal-to-zygotic transition targets actin to promote robustness during morphogenesis. PLoS Genet. 2013 Nov; 9(11):e1003901.
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Renal cell carcinoma with novel VCL-ALK fusion: new representative of ALK-associated tumor spectrum. Mod Pathol. 2011 Mar; 24(3):430-42.
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GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions. Circ Res. 2004 Apr 30; 94(8):1041-9.
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The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells. Clin Cancer Res. 2004 Jan 15; 10(2):658-67.
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Elastin induces myofibrillogenesis via a specific domain, VGVAPG. Matrix Biol. 2003 Sep; 22(5):409-25.
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A critical role for elastin signaling in vascular morphogenesis and disease. Development. 2003 Jan; 130(2):411-23.
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Lateral zone of cell-cell adhesion as the major fluid shear stress-related signal transduction site. Circ Res. 2000 Mar 03; 86(4):425-33.
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Macromolecular composition of stress fiber-plasma membrane attachment sites in endothelial cells in situ. Circ Res. 1996 Nov; 79(5):1000-6.
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Mutually exclusive distribution of the focal adhesion associated proteins and the erythrocyte membrane skeleton proteins in the human fibroblast plasma membrane undercoat. Cell Struct Funct. 1996 Feb; 21(1):27-39.