"CD11c Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
| Descriptor ID |
D039521
|
| MeSH Number(s) |
D12.776.395.550.200.074.875 D12.776.395.550.200.275.500 D12.776.543.550.200.093.875 D12.776.543.550.200.275.500 D12.776.543.750.705.408.100.200 D12.776.543.750.705.408.600.100.500 D12.776.543.750.705.833.249.500 D23.050.301.350.074.074 D23.050.301.350.275.500
|
| Concept/Terms |
CD11c Antigen- CD11c Antigen
- Antigen, CD11c
- Antigens, CD11c
- CD11c Antigens
- Integrin alphaX
- alphaX, Integrin
- Leu-M5 Antigens
- Antigens, Leu-M5
- Leu M5 Antigens
|
Below are MeSH descriptors whose meaning is more general than "CD11c Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD11c Antigen".
This graph shows the total number of publications written about "CD11c Antigen" by people in this website by year, and whether "CD11c Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "CD11c Antigen" by people in Profiles.
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CD5L attenuates allergic airway inflammation by expanding CD11chigh alveolar macrophages and inhibiting NLRP3 inflammasome activation via HDAC2. Immunology. 2022 11; 167(3):384-397.
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CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease. Front Immunol. 2021; 12:745893.
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CD11c participates in triggering acute graft-versus-host disease during bone marrow transplantation. Immunology. 2021 09; 164(1):148-160.
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Deficiency of Stat1 in CD11c+ Cells Alters Adipose Tissue Inflammation and Improves Metabolic Dysfunctions in Mice Fed a High-Fat Diet. Diabetes. 2021 03; 70(3):720-732.
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An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes. J Immunol. 2020 11 15; 205(10):2806-2820.
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Kinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer. Int J Radiat Oncol Biol Phys. 2018 11 01; 102(3):593-600.
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Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):6786-6791.
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Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa. Sci Rep. 2017 10 23; 7(1):13829.
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Effects of n-3 fatty acid treatment on monocyte phenotypes in humans with hypertriglyceridemia. J Clin Lipidol. 2017 Nov - Dec; 11(6):1361-1371.
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Cholesterol Accumulation in CD11c+ Immune Cells Is a Causal and Targetable Factor in Autoimmune Disease. Immunity. 2016 12 20; 45(6):1311-1326.