"DNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
| Descriptor ID |
D004265
|
| MeSH Number(s) |
D08.811.277.040.025.159 D08.811.399.340
|
| Concept/Terms |
DNA Helicases- DNA Helicases
- Helicases, DNA
- DNA Unwinding Proteins
- Unwinding Proteins, DNA
ATP-Dependent DNA Helicases- ATP-Dependent DNA Helicases
- ATP Dependent DNA Helicases
- DNA Helicases, ATP-Dependent
- Helicases, ATP-Dependent DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DNA Helicases".
This graph shows the total number of publications written about "DNA Helicases" by people in this website by year, and whether "DNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 6 | 0 | 6 |
| 2003 | 6 | 1 | 7 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 5 | 8 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 4 | 3 | 7 |
| 2011 | 5 | 0 | 5 |
| 2012 | 2 | 3 | 5 |
| 2013 | 3 | 4 | 7 |
| 2014 | 0 | 4 | 4 |
| 2015 | 1 | 4 | 5 |
| 2016 | 6 | 3 | 9 |
| 2017 | 6 | 6 | 12 |
| 2018 | 3 | 2 | 5 |
| 2019 | 2 | 3 | 5 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 4 | 6 | 10 |
| 2023 | 0 | 9 | 9 |
| 2024 | 2 | 3 | 5 |
| 2025 | 3 | 1 | 4 |
| 2026 | 3 | 1 | 4 |
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click here.
Below are the most recent publications written about "DNA Helicases" by people in Profiles.
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Overcoming menin inhibitor resistance in AML cells with combinations including BET proteins and a dual BRG1/BRM inhibitor. Blood. 2026 Jun 04; 147(23):2809-2820.
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SMARCAL1 is a new osteosarcoma predisposition gene. J Natl Cancer Inst. 2026 Jun 01; 118(6):1120-1125.
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Frequent synaptophysin expression in SMARCA4-deficient undifferentiated carcinoma of the oesophagus: a diagnostic pitfall with therapeutic implications. J Clin Pathol. 2026 Mar 19; 79(4):229-237.
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Paediatric Therapeutic Development Workshop on rhabdoid tumours. Br J Cancer. 2026 Jun; 134(11):1510-1528.
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A novel cardiomyopathy phenotype linked to a CHD7 missense variant. Sci Rep. 2025 Jun 03; 15(1):19429.
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Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations. Blood Cancer J. 2025 03 15; 15(1):40.
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Frontal lobe intra-axial schwannoma harboring a CHD7::VGLL3 fusion and heterozygous TSC2 p.F1510del mutation in a young child. Mol Biol Rep. 2025 Jan 10; 52(1):112.
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ATRX silences Cartpt expression in osteoblastic cells during skeletal development. J Clin Invest. 2025 Jan 02; 135(1).
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Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences. Nat Genet. 2024 Sep; 56(9):1832-1840.
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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor. Blood. 2024 05 16; 143(20):2059-2072.