Item Type | Name |
Academic Article
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Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway.
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Academic Article
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Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer.
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Academic Article
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Mismatch repair gene expression and genetic instability in testicular germ cell tumor.
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Academic Article
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Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects.
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Academic Article
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Mortality in the randomized, controlled lung intergroup trial of isotretinoin.
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Academic Article
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Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer.
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Academic Article
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A phase II study of gefitinib for aggressive cutaneous squamous cell carcinoma of the head and neck.
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Academic Article
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ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.
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Academic Article
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Fibulin-2 is a driver of malignant progression in lung adenocarcinoma.
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Academic Article
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Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers.
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Academic Article
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Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer.
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Academic Article
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Smoking-related genomic signatures in non-small cell lung cancer.
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Academic Article
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Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model.
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Academic Article
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Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma.
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Academic Article
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Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.
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Academic Article
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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
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Academic Article
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Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor ?2 expression.
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Academic Article
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Activating enhancer-binding protein-2? nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection.
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Academic Article
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G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer.
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Academic Article
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Characterizing the cancer genome in lung adenocarcinoma.
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Academic Article
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Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.
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Academic Article
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Phase II trials of imatinib mesylate and docetaxel in patients with metastatic non-small cell lung cancer and head and neck squamous cell carcinoma.
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Academic Article
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MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression.
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Concept
|
Jurkat Cells
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Concept
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Lymphoma, T-Cell
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Concept
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Cell Movement
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Concept
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Cell Nucleolus
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Concept
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Cell Death
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Concept
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Active Transport, Cell Nucleus
|
Concept
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Lymphoma, Large B-Cell, Diffuse
|
Concept
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Carcinoma, Non-Small-Cell Lung
|
Concept
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Carcinoma, Signet Ring Cell
|
Concept
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Lymphoma, T-Cell, Peripheral
|
Concept
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Epithelial Cells
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
|
Concept
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Goblet Cells
|
Concept
|
Alveolar Epithelial Cells
|
Concept
|
Cell Lineage
|
Concept
|
Receptors, Antigen, T-Cell
|
Concept
|
Neoplastic Stem Cells
|
Concept
|
T-Cell Antigen Receptor Specificity
|
Concept
|
Neoplasms, Germ Cell and Embryonal
|
Concept
|
HeLa Cells
|
Concept
|
Cell Nucleus
|
Concept
|
Cell Division
|
Concept
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Dendritic Cells
|
Concept
|
Cell Cycle Proteins
|
Concept
|
Cell Cycle
|
Concept
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Cell Membrane
|
Concept
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Cell Culture Techniques
|
Concept
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Clone Cells
|
Concept
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Cell Transformation, Neoplastic
|
Concept
|
Carcinoma, Renal Cell
|
Concept
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Receptors, Cell Surface
|
Concept
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Cell Survival
|
Concept
|
Cell Communication
|
Concept
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Cell Adhesion
|
Concept
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Cell Adhesion Molecules
|
Concept
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Carcinoma, Basal Cell
|
Concept
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Endothelial Cells
|
Concept
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Cell Respiration
|
Concept
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Carcinoma, Squamous Cell
|
Concept
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Cell Adhesion Molecules, Neuronal
|
Concept
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Neoplastic Cells, Circulating
|
Concept
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Lymphoma, Large-Cell, Anaplastic
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Concept
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Proliferating Cell Nuclear Antigen
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Concept
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Cell Growth Processes
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Concept
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Cell Line
|
Concept
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Tumor Stem Cell Assay
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Concept
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Tumor Cells, Cultured
|
Concept
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Carcinoma, Transitional Cell
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Concept
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Carcinoma, Large Cell
|
Concept
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B-Cell Maturation Antigen
|
Concept
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Cell Differentiation
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Concept
|
Oxyphil Cells
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Concept
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Adenocarcinoma, Clear Cell
|
Concept
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Leukemia, Lymphocytic, Chronic, B-Cell
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Concept
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Neural Cell Adhesion Molecules
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Concept
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Carcinoma, Small Cell
|
Concept
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Cell Line, Tumor
|
Concept
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Plasma Cells
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Concept
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Small Cell Lung Carcinoma
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Concept
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Neoplasms, Squamous Cell
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Concept
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Carcinoma, Merkel Cell
|
Concept
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HT29 Cells
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Concept
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Cells, Cultured
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Concept
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Stem Cells
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Concept
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Caco-2 Cells
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Concept
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Cell Hypoxia
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Concept
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Cell Separation
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Concept
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Receptors, Antigen, T-Cell, gamma-delta
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Concept
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Cell Proliferation
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Concept
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Cell Count
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Academic Article
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SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines.
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Academic Article
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Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells.
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Academic Article
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Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR-?) is associated with PDGFRB gene copy number gain in sarcomatoid non-small-cell lung cancer.
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Academic Article
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Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.
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Academic Article
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Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors.
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Academic Article
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c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.
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Academic Article
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ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.
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Academic Article
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Epithelial-to-mesenchymal transition in the development and progression of adenocarcinoma and squamous cell carcinoma of the lung.
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Academic Article
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Primary oncocytic adenocarcinomas of the lung: a clinicopathologic, immunohistochemical, and molecular biologic analysis of 16 cases.
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Academic Article
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Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.
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Academic Article
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Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.
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Academic Article
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Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis.
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Academic Article
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Sox10-positive sustentacular cells in neuroendocrine carcinoma of the lung.
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Academic Article
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Clinicopathological and immunohistochemical analysis of spindle-cell carcinoid tumour of the lung.
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Academic Article
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Differential expression of somatostatin receptors 1-5 in neuroendocrine carcinoma of the lung.
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Academic Article
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Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma.
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Academic Article
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EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma.
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Academic Article
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Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer.
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Academic Article
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Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma.
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Academic Article
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Eosinophilic globules in pigmented spindle cell nevus.
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Academic Article
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[Cervix uteri cancer: determination of DNA content by means of cytophotometry].
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Academic Article
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Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: association with human papillomavirus type.
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Academic Article
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Genetic changes in the spectrum of neuroendocrine lung tumors.
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Academic Article
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Comparison of features of human lung cancer cell lines and their corresponding tumors.
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Academic Article
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Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer.
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Academic Article
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Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines.
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Academic Article
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Molecular changes in the bronchial epithelium of patients with small cell lung cancer.
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Academic Article
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Identification of novel cellular targets in biliary tract cancers using global gene expression technology.
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Academic Article
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EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.
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Academic Article
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High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.
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Academic Article
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Application of a methylation gene panel by quantitative PCR for lung cancers.
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Academic Article
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Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung cancer.
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Academic Article
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Molecular pathogenesis of early-stage non-small cell lung cancer and a proposal for tissue banking to facilitate identification of new biomarkers.
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Academic Article
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Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion.
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Academic Article
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Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene.
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Academic Article
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Germ-line and somatic presentations of the EGFR T790M mutation in lung cancer.
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Academic Article
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Chromosomal deletions and progression of premalignant lesions: less is more.
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Academic Article
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Amplification of chromosomal segment 4q12 in non-small cell lung cancer.
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Academic Article
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Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells.
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Academic Article
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Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
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Academic Article
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Differential impacts of insulin-like growth factor-binding protein-3 (IGFBP-3) in epithelial IGF-induced lung cancer development.
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Academic Article
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Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer.
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Academic Article
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The role of PKR/eIF2a signaling pathway in prognosis of non-small cell lung cancer.
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Academic Article
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Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
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Academic Article
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Field cancerization in non-small cell lung cancer: implications in disease pathogenesis.
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Academic Article
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Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.
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Academic Article
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Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion.
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Academic Article
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Diagnosis of lung cancer in small biopsies and cytology: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification.
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Academic Article
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Prognostic value of LIPC in non-small cell lung carcinoma.
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Academic Article
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Perfecting the fine-needle aspirate cell block.
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Academic Article
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Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.
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Academic Article
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Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial.
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Academic Article
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An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
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Academic Article
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[2 rare cases of a presentation of endometrial cancer].
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Academic Article
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[Proliferating cell nuclear antigen (PCNA) in patients with malabsorption syndrome: comparative study with morphometric parameters].
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Academic Article
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Allele-specific mutations involved in the pathogenesis of endemic gallbladder carcinoma in Chile.
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Academic Article
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Proliferating cell nuclear antigen in gallbladder carcinoma.
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Academic Article
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[Stomach and gallbladder cancer. Analysis of cell cycle phases by means of flow cytometry].
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Academic Article
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[Epidermoid carcinoma of the cervix uteri: molecular abnormalities of p53 and rb genes].
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Academic Article
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FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations.
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Academic Article
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Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene.
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Academic Article
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Human papillomavirus type 16 is detected in transitional cell carcinomas and squamotransitional cell carcinomas of the cervix and endometrium.
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Academic Article
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Mutation analysis of the PTEN/MMAC1 gene in lung cancer.
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Academic Article
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Comparison of features of human breast cancer cell lines and their corresponding tumors.
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Academic Article
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Deletions of chromosome 4 at multiple sites are frequent in malignant mesothelioma and small cell lung carcinoma.
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Academic Article
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Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma.
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Academic Article
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Enrichment of epithelial cells for molecular studies.
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Academic Article
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K-ras and p53 mutations in the pathogenesis of classical and goblet cell carcinoids of the appendix.
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Academic Article
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Multiple regions of chromosome 4 demonstrating allelic losses in breast carcinomas.
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Academic Article
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Molecular identification of metastatic cancer to the skin using laser capture microdissection: a case report.
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Academic Article
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High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss.
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Academic Article
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Microdissection and the study of cancer pathways.
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Academic Article
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Bronchioalveolar cell carcinoma: radiologic appearance and dilemmas in the assessment of response.
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Academic Article
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Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence.
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Academic Article
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Aberrant methylation of Reprimo in human malignancies.
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Academic Article
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Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
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Academic Article
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Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry.
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Academic Article
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Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.
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Academic Article
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Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer.
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Academic Article
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Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer.
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Academic Article
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Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system.
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Academic Article
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miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1.
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Academic Article
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Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer.
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Academic Article
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Exponential decay nonlinear regression analysis of patient survival curves: preliminary assessment in non-small cell lung cancer.
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Academic Article
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Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation.
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Academic Article
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Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
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Academic Article
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Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence.
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Academic Article
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Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells.
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Academic Article
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Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance.
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Academic Article
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Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients.
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Academic Article
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Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis.
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Academic Article
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Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters.
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Academic Article
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New strategies in squamous cell carcinoma of the lung: identification of tumor drivers to personalize therapy.
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Academic Article
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Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy.
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Academic Article
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Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer.
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Academic Article
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Tissue platinum concentration and tumor response in non-small-cell lung cancer.
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Academic Article
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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
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Academic Article
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Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
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Academic Article
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19q13-ERCC1 gene copy number increase in non--small-cell lung cancer.
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Academic Article
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DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-?-driven epithelial-mesenchymal transition.
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Academic Article
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miR-93-directed downregulation of DAB2 defines a novel oncogenic pathway in lung cancer.
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Academic Article
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Identification of a subset of human non-small cell lung cancer patients with high PI3K? and low PTEN expression, more prevalent in squamous cell carcinoma.
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Academic Article
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Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer.
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Academic Article
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CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.
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Academic Article
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Gallbladder cancer in Chile. A report on 54 potentially resectable tumors.
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Academic Article
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[Immunohistochemical expression of epidermal growth factor receptor (EGFR) in epidermoid carcinoma of the cervix uteri and its precursor lesions].
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Academic Article
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DNA analysis at p53 locus in carcinomas arising from pleomorphic adenomas of salivary glands: comparison of molecular study and p53 immunostaining.
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Academic Article
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Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.
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Academic Article
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Molecular abnormalities associated with endocrine tumors of the uterine cervix.
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Academic Article
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Genetic changes during the multistage pathogenesis of human papillomavirus positive and negative vulvar carcinomas.
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Academic Article
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Use of archival fine-needle aspirates for the allelotyping of tumors.
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Academic Article
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Presence of simian virus 40 sequences in malignant mesotheliomas and mesothelial cell proliferations.
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Academic Article
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High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.
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Academic Article
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Molecular analysis of synchronous and metachronous tumors of the lung: impact on management and prognosis.
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Academic Article
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Clonality of combined tumors.
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Academic Article
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Distinct K-ras mutation pattern characterizes signet ring cell colorectal carcinoma.
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Academic Article
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Nuclear morphometry as a biomarker for bronchial intraepithelial neoplasia: correlation with genetic damage and cancer development.
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Academic Article
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Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.
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Academic Article
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Cystic bronchioloalveolar cell carcinoma.
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Academic Article
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Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
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Academic Article
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Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions.
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Academic Article
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KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer.
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Academic Article
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A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer.
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Academic Article
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Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensional organotypic air-liquid interface method.
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Academic Article
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The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer.
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Academic Article
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Lung cancer preneoplasia.
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Academic Article
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Molecular pathology of thymic epithelial neoplasms.
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Academic Article
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PIK3CA mutations and copy number gains in human lung cancers.
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Academic Article
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HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors.
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Academic Article
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Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation.
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Academic Article
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Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development.
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Academic Article
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Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.
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Academic Article
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EphA2 in the early pathogenesis and progression of non-small cell lung cancer.
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Academic Article
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Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions.
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Academic Article
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Biological activity of celecoxib in the bronchial epithelium of current and former smokers.
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Academic Article
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SSTR2-based reporters for assessing gene transfer into non-small cell lung cancer: evaluation using an intrathoracic mouse model.
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Academic Article
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Phase II study of dasatinib in patients with advanced non-small-cell lung cancer.
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Academic Article
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Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers.
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Academic Article
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A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis.
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Academic Article
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Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer.
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Academic Article
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The impact of phosphorylated AMP-activated protein kinase expression on lung cancer survival.
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Academic Article
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Evolving concepts in lung carcinogenesis.
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Academic Article
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STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma.
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Academic Article
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Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development.
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Academic Article
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miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers.
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Academic Article
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Prognostic impact of vitamin B6 metabolism in lung cancer.
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Academic Article
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Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trial.
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Academic Article
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An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
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Academic Article
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CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.
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Academic Article
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Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma.
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Academic Article
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Computed tomography RECIST assessment of histopathologic response and prediction of survival in patients with resectable non-small-cell lung cancer after neoadjuvant chemotherapy.
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Academic Article
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A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients.
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Academic Article
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RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.
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Academic Article
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Prognostic significance of combinations of RNA-dependent protein kinase and EphA2 biomarkers for NSCLC.
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Academic Article
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Feasibility of image-guided transthoracic core-needle biopsy in the BATTLE lung trial.
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Academic Article
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Uncommon epidermal growth factor receptor mutations in non-small cell lung cancer and their mechanisms of EGFR tyrosine kinase inhibitors sensitivity and resistance.
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Academic Article
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Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial.
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Academic Article
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The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors.
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Academic Article
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RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner.
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Academic Article
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Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?
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Academic Article
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Prediction of survival in resected non-small cell lung cancer using a protein expression-based risk model: implications for personalized chemoprevention and therapy.
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Academic Article
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TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients.
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Academic Article
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Membrane carbonic anhydrase IX expression and relapse risk in resected stage I-II non-small-cell lung cancer.
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Academic Article
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[Immunohistochemical demonstration of pepsinogens I and II in the gallbladder].
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Academic Article
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[Determination of DNA content using cytophotometry in nuclear suspension conserved for prolonged periods (preliminary study)].
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Academic Article
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[Proliferating cell nuclear antigen in cervical cancer and precursor lesions].
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Academic Article
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Allelic losses at chromosome 3p are seen in human papilloma virus 16 associated transitional cell carcinoma of the cervix.
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Academic Article
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Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome.
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Academic Article
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Molecular changes in second primary lung and breast cancers after therapy for Hodgkin's disease.
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Academic Article
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Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
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Academic Article
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Microsatellite analysis of synchronous and metachronous tumors: a tool for double primary tumor and metastasis assessment.
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Academic Article
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Gallbladder cancer: lessons from a rare tumour.
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Academic Article
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High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
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Academic Article
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Cyclic AMP response element-binding protein overexpression: a feature associated with negative prognosis in never smokers with non-small cell lung cancer.
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Academic Article
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Prognostic significance of RNA-dependent protein kinase on non-small cell lung cancer patients.
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Academic Article
|
Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy.
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Academic Article
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Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts.
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Academic Article
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Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion.
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Academic Article
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Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
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Cellular location and expression of Na+, K+ -ATPase a subunits affect the anti-proliferative activity of oleandrin.
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Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling.
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ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer.
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A reevaluation of CD22 expression in human lung cancer.
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Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer.
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[Nucleolar organizer regions in uterine cervical cancer and its precursor epithelial lesions].
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Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma.
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Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.
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Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis.
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Histologic evaluation of bronchial squamous lesions: any role in lung cancer risk assessment?
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[Pathogenic role of PTEN tumor suppressor gene in ovarian cancer associated to endometriosis].
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Aromatase expression predicts survival in women with early-stage non small cell lung cancer.
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A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras.
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Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer.
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Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma.
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High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation.
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Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.
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NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.
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Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma.
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Presence of simian virus 40 sequences in malignant pleural, peritoneal and noninvasive mesotheliomas.
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Academic Article
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Molecular testing of non-small cell lung carcinoma biopsy and cytology specimens.
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Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications.
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Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer.
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VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy.
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Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer.
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Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway.
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Vandetanib and indwelling pleural catheter for non-small-cell lung cancer with recurrent malignant pleural effusion.
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Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma.
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A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.
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Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.
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Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study.
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A phase I/II study combining erlotinib and dasatinib for non-small cell lung cancer.
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Academic Article
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Current concepts on the molecular pathology of non-small cell lung carcinoma.
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Academic Article
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ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.
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Academic Article
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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.
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Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition.
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Genetic mutation of p53 and suppression of the miR-17~92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling.
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Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
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Academic Article
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Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer.
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Academic Article
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Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines.
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Academic Article
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Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival.
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Academic Article
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RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells.
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RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer.
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Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer.
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Academic Article
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Adding Erlotinib to Chemoradiation Improves Overall Survival but Not Progression-Free Survival in Stage III Non-Small Cell Lung Cancer.
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Academic Article
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Regulation of AURKC expression by CpG island methylation in human cancer cells.
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Academic Article
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Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer.
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Academic Article
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Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment.
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Academic Article
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Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.
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Academic Article
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Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?
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Academic Article
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Pleuropulmonary Meningothelial Proliferations: Evidence for a Common Histogenesis.
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Molecular Testing for Treatment of Metastatic Non-Small Cell Lung Cancer: How to Implement Evidence-Based Recommendations.
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LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells.
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Academic Article
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From Uniplex to Multiplex Molecular Profiling in Advanced Non-Small Cell Lung Carcinoma.
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Academic Article
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Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations.
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Academic Article
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NRF2 regulates serine biosynthesis in non-small cell lung cancer.
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ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis.
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Academic Article
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Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway.
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Multiplatform-based molecular subtypes of non-small-cell lung cancer.
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Academic Article
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Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties.
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Academic Article
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Molecular testing for treatment of metastatic non-small cell lung cancer
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Academic Article
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An expression signature as an aid to the histologic classification of non-small cell lung cancer
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Academic Article
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Regulation of AURKC expression by CpG island methylation in human cancer cells
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Academic Article
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Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations
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Academic Article
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LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells
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Academic Article
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The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells
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Academic Article
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Human papillomavirus, lichen sclerosis and vulvar squamous cell carcinoma
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Academic Article
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Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer
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Academic Article
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Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties
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Academic Article
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Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer
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Academic Article
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Multiplatform-based molecular subtypes of non-small-cell lung cancer
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Academic Article
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Corrigendum to "PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer" [Neoplasia 18 (2016) 282-293]
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Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis
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Academic Article
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Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer
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Academic Article
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Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations
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Academic Article
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Methodological and Practical Challenges for Personalized Therapies in Non-Small-Cell Lung Cancer
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Academic Article
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Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
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Academic Article
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Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition
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STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T-cell activity in the lung tumor microenvironment
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Academic Article
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Density, distribution, and composition of immune infiltrates correlate with survival in Merkel cell carcinoma
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Academic Article
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LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells
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Academic Article
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Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines
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Academic Article
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Image analysis-based assessment of PD-L1 and tumor-associated immune cells density supports distinct intratumoral microenvironment groups in non-small cell lung carcinoma patients
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Academic Article
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Current concepts on the molecular pathology of non-small cell lung carcinoma
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Academic Article
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NRF2 regulates serine biosynthesis in non-small cell lung cancer
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Academic Article
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Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition
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Academic Article
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The international association for the study of lung cancer consensus statement on optimizing management of EGFR mutation-positive non-small cell lung cancer
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Academic Article
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Sarcomatoid Renal Cell Carcinoma Has a Distinct Molecular Pathogenesis, Driver Mutation Profile, and Transcriptional Landscape.
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Academic Article
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Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome.
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Academic Article
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RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer.
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Academic Article
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Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGF?RIII-p38MAPK-pS249/T252RB Pathway.
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Academic Article
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The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.
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Academic Article
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Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis.
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Academic Article
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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.
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Academic Article
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Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.
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Academic Article
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Squamous Cell Carcinoma - Similarities and Differences among Anatomical Sites.
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Academic Article
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LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells.
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Academic Article
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A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition.
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Academic Article
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Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.
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Academic Article
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Optimizing the DNA yield for molecular analysis from cytologic preparations.
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Academic Article
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STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
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Academic Article
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Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations.
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Academic Article
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Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer.
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Academic Article
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Validation of SCT Methylation as a Hallmark Biomarker for Lung Cancers.
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Academic Article
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Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases.
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Academic Article
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KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib.
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Academic Article
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Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma.
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Academic Article
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The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer: Status in 2016.
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Academic Article
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Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
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Academic Article
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Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity.
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Academic Article
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Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations.
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Academic Article
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ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.
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Academic Article
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Spindle cell and pleomorphic ("sarcomatoid") carcinomas of the lung: an immunohistochemical analysis of 86 cases.
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Academic Article
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Primary Mediastinal Yolk Sac Tumors: An Immunohistochemical Analysis of 14 Cases.
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Academic Article
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IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.
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Academic Article
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An Expression Signature as an Aid to the Histologic Classification of Non-Small Cell Lung Cancer.
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Academic Article
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Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer.
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Academic Article
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Image Analysis-based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-small Cell Lung Carcinoma Patients.
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Academic Article
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Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
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Academic Article
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The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.
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Academic Article
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The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells.
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Academic Article
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PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis.
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Academic Article
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Comprehensive Computational Pathological Image Analysis Predicts Lung Cancer Prognosis.
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Academic Article
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The ISG15-specific protease USP18 regulates stability of PTEN.
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Academic Article
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Comprehensive evaluation of published gene expression prognostic signatures for biomarker-based lung cancer clinical studies.
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Academic Article
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Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function.
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Academic Article
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XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
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Academic Article
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Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers.
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Academic Article
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Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.
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Academic Article
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A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer.
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Academic Article
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Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer.
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Academic Article
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Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.
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Academic Article
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CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
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Academic Article
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JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non-Small Cell Lung Cancer.
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Academic Article
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Expression of PD-1 and PD-L1 in thymic epithelial neoplasms.
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Academic Article
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VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer.
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Academic Article
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GLI1 Blockade Potentiates the Antitumor Activity of PI3K Antagonists in Lung Squamous Cell Carcinoma.
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Academic Article
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Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.
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Academic Article
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Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer.
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Academic Article
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Study of Preanalytic and Analytic Variables for Clinical Next-Generation Sequencing of Circulating Cell-Free Nucleic Acid.
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Academic Article
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The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.
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Academic Article
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TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.
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Academic Article
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Update on EGFR Mutational Testing and the Potential of Noninvasive Liquid Biopsy in Non-Small-cell Lung Cancer.
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Academic Article
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Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with ?-blockers.
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Academic Article
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A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling.
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Academic Article
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Programmed cell death ligand 1 and tumor-infiltrating lymphocyte status in patients with renal cell carcinoma and sarcomatoid dedifferentiation.
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Academic Article
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Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
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Academic Article
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Serum MicroRNA-150 Predicts Prognosis for Early-Stage Non-Small Cell Lung Cancer and Promotes Tumor Cell Proliferation by Targeting Tumor Suppressor Gene SRCIN1.
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Academic Article
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Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies.
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Academic Article
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Programmed Death Cell Ligand 1 (PD-L1) Is Associated With Survival in Stage I Non-Small Cell Lung Cancer.
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Academic Article
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Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer.
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Academic Article
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Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma.
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Academic Article
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Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer.
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Academic Article
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Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors.
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Academic Article
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Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors.
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Academic Article
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Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.
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Academic Article
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Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer.
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Academic Article
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Induction Cisplatin Docetaxel Followed by Surgery and Erlotinib in Non-Small Cell Lung Cancer.
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Academic Article
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Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer.
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Academic Article
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Multiregion gene expression profiling reveals heterogeneity in molecular subtypes and immunotherapy response signatures in lung cancer.
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Academic Article
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CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.
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Academic Article
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Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.
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Academic Article
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De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer.
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Academic Article
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Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial.
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Academic Article
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Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer.
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Academic Article
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Liquid Biopsy for Advanced Non-Small Cell Lung?Cancer (NSCLC): A Statement Paper from the?IASLC.
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Academic Article
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Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
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Academic Article
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The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer.
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Academic Article
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HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress.
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Academic Article
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STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
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Academic Article
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Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.
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Academic Article
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Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
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Academic Article
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Validation of the 12-gene Predictive Signature for Adjuvant Chemotherapy Response in Lung Cancer.
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Academic Article
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Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.
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Academic Article
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5 protein-based signature for resectable lung squamous cell carcinoma improves the prognostic performance of the TNM staging.
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Academic Article
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PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.
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Academic Article
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Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.
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Academic Article
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Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.
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Academic Article
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METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
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Academic Article
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Rational "Error Elimination" Approach to Evaluating Molecular Barcoded Next-Generation Sequencing Data Identifies Low-Frequency Mutations in Hematologic Malignancies.
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Academic Article
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B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density.
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Academic Article
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ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.
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Academic Article
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Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
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Academic Article
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PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer.
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Academic Article
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Liquid biopsy assay for lung carcinoma using centrifuged supernatants from fine-needle aspiration specimens.
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Academic Article
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Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer.
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Academic Article
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Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung.
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Academic Article
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A novel protein-based prognostic signature improves risk stratification to guide clinical management in early-stage lung adenocarcinoma patients.
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Academic Article
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Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.
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Academic Article
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Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
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Concept
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A549 Cells
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Concept
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Myeloid-Derived Suppressor Cells
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Concept
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Cell-Free Nucleic Acids
|
Concept
|
THP-1 Cells
|
Concept
|
HEK293 Cells
|
Concept
|
Single-Cell Analysis
|
Concept
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Cell Cycle Checkpoints
|
Concept
|
M Phase Cell Cycle Checkpoints
|
Concept
|
G1 Phase Cell Cycle Checkpoints
|
Concept
|
Merkel cell polyomavirus
|
Concept
|
Inducible T-Cell Co-Stimulator Protein
|
Concept
|
V-Set Domain-Containing T-Cell Activation Inhibitor 1
|
Concept
|
Programmed Cell Death 1 Receptor
|
Concept
|
MCF-7 Cells
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Academic Article
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YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
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Academic Article
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Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer.
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Academic Article
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Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma.
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Academic Article
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Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer.
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Academic Article
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Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer.
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Academic Article
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Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer.
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Academic Article
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Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.
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Academic Article
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Characterization and Comparison of GITR Expression in Solid Tumors.
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Academic Article
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Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy.
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Academic Article
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A proposal for pathologic processing of breast implant capsules in patients with suspected breast implant anaplastic large cell lymphoma.
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Academic Article
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Development and Application of Duplex Sequencing Strategy for Cell-Free DNA-Based Longitudinal Monitoring of Stage IV Colorectal Cancer.
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Academic Article
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Non-invasive genotyping of metastatic colorectal cancer using circulating cell free DNA.
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Academic Article
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Oncogenic enhancer of zeste homolog 2 is an actionable target in patients with non-small cell lung cancer.
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Academic Article
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Lymphovascular Invasion Is Associated With Mutational Burden and PD-L1 in Resected Lung Cancer.
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Academic Article
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Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
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Academic Article
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Nicotinic acetylcholine receptor expression in human airway correlates with lung function.
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Academic Article
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The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma.
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Academic Article
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Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation.
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Academic Article
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From clinical specimens to human cancer preclinical models-a journey the NCI-cell line database-25 years later.
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Academic Article
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Correction: Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation.
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Academic Article
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High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer.
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Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance.
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PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee.
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RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.
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Achieving complete remission in CLL patients treated with ibrutinib: clinical significance and predictive factors.
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Comprehensive T cell repertoire characterization of non-small cell lung cancer.
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New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
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A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non-Small Cell Lung Cancer.
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Agreement on Major Pathological Response in NSCLC Patients Receiving Neoadjuvant Chemotherapy.
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18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer.
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T-Cell Repertoire in Combination with T-Cell Density Predicts Clinical Outcomes in Patients with Merkel Cell Carcinoma.
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Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort.
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.
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Programmed Death-Ligand 1 Heterogeneity and Its Impact on Benefit From Immune Checkpoint Inhibitors in NSCLC.
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Hypertrophic lichenoid dermatitis immune-related adverse event during combined immune checkpoint and exportin inhibitor therapy: A diagnostic pitfall for superficially invasive squamous cell carcinoma.
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Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers: Results From a Retrospective Multicenter Cohort Study.
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An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.
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The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker: A Perspective from the International Association for the Study of Lung Cancer Pathology Committee.
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Interplay between estrogen and Stat3/NF-?B-driven immunomodulation in lung cancer.
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Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment.
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Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion.
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Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC.
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Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity.
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The value of interventional radiology in clinical trial teams: experience from the BATTLE lung cancer trials.
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Altered Regulation of HIF-1a in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype.
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Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax.
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Pathologic Assessment of Lung Squamous Cell Carcinoma After Neoadjuvant Immunotherapy.
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Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.
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CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma.
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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities.
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Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
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Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer.
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PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer.
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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).
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Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial.
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Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib?onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit.
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Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.
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Corrigendum to "PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer" [Neoplasia 18 (2016) 282-293].
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Challenges in Facing the Lung Cancer Epidemic and Treating Advanced Disease in Latin America.
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The International Association for the Study of Lung Cancer Global Survey on Programmed Death-Ligand 1 Testing for NSCLC.
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Global analysis of shared T?cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery.
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Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer.
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CD8+ T cells inhibit metastasis and CXCL4 regulates its function.
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Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients.
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Evaluation of Pathologic Response in Lymph Nodes of Patients With Lung Cancer Receiving Neoadjuvant Chemotherapy.
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Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity.
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Immuno-profiling and cellular spatial analysis using five immune oncology multiplex immunofluorescence panels for paraffin tumor tissue.
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Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing.
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Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features.
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Multiplex Immunofluorescence Tyramide Signal Amplification for Immune Cell Profiling of Paraffin-Embedded Tumor Tissues.
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The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
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Liquid Biopsy for Advanced NSCLC: A Consensus Statement From the International Association for the Study of Lung Cancer.
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A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers.
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Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial.
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Pretreatment Tissue TCR Repertoire Evenness Is Associated with Complete Pathologic Response in Patients with NSCLC Receiving Neoadjuvant Chemoimmunotherapy.
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Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer.
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Artificial intelligence strategy integrating morphologic and architectural biomarkers provides robust diagnostic accuracy for disease progression in chronic lymphocytic leukemia.
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BCL-W expression associates with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified.
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The immunogenomic landscape of resected intrahepatic cholangiocarcinoma.
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NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis.
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Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer.
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Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer.
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PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
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Effector memory cytotoxic CD3+/CD8+/CD45RO+ T cells are predictive of good survival and a lower risk of recurrence in triple-negative breast cancer.
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The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics.
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Surgical approach does not influence changes in circulating immune cell populations following lung cancer resection.
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Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes.
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Germline and Somatic Smoothened Mutations in Non-Small-Cell Lung Cancer Are Potentially Responsive to Hedgehog Inhibitor Vismodegib.
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ESMO expert consensus statements on the management of EGFR mutant non-small-cell lung cancer.
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MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers.
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Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer.
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Distinct Immune Gene Programs Associated with Host Tumor Immunity, Neoadjuvant Chemotherapy, and Chemoimmunotherapy in Resectable NSCLC.
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T?cells.
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Impact of Region-of-Interest Size on Immune Profiling Using Multiplex Immunofluorescence Tyramide Signal Amplification for Paraffin-Embedded Tumor Tissues.
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The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8+ cytotoxic T-cell response.
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Pathological Response and Immune Biomarker Assessment in Non-Small-Cell Lung Carcinoma Receiving Neoadjuvant Immune Checkpoint Inhibitors.
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Game of clones: Battles in the field of carcinogenesis.
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The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma.
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Predictive Biomarkers for Immunotherapy in Lung Cancer: Perspective From the International Association for the Study of Lung Cancer Pathology Committee.
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Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non-small cell lung cancer.
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Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.
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Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
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A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response.
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Neoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial.
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Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer.
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Netie: inferring the evolution of neoantigen-T cell interactions in tumors.
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Phase II study of durvalumab (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
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Analysis of Immune Intratumor Heterogeneity Highlights Immunoregulatory and Coinhibitory Lymphocytes as Hallmarks of?Recurrence in Stage I Non-Small Cell Lung Cancer.
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Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.
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PD-L1+ macrophages are associated with favorable features in primary mediastinal (thymic) large B-cell lymphoma.
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Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers.
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Immune cellular patterns of distribution affect outcomes of patients with non-small cell lung cancer.
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Phase II trial of neoadjuvant sitravatinib plus nivolumab in patients undergoing nephrectomy for locally advanced clear cell renal cell carcinoma.
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Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer.
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Gene expression profiling and multiplex immunofluorescence analysis of bullous pemphigoid immune-related adverse event reveal upregulation of toll-like receptor 4/complement-induced innate immune response and increased density of TH 1 T-cells.
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Predicting benefit from immune checkpoint inhibitors in patients with non-small-cell lung cancer by CT-based ensemble deep learning: a retrospective study.
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Pathologist-initiated reflex testing for biomarkers in non-small-cell lung cancer: expert consensus on the rationale and considerations for implementation.
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MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
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Quantitative multiplexed imaging technologies for single-cell analysis to assess predictive markers for immunotherapy in thoracic immuno-oncology: promises and challenges.
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EMT activates exocytotic Rabs to coordinate invasion and immunosuppression in lung cancer.
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Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma.
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Stereotactic ablative radiotherapy with or without immunotherapy for early-stage or isolated lung parenchymal recurrent node-negative non-small-cell lung cancer: an open-label, randomised, phase 2 trial.
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International Association for the Study of Lung Cancer Study of Reproducibility in Assessment of Pathologic Response in Resected Lung Cancers After Neoadjuvant Therapy.
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Genomic Staging of Multifocal Lung Squamous Cell Carcinomas Is Independent of the Comprehensive Morphologic Assessment.
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Autotaxin suppresses cytotoxic T cells via LPAR5 to promote anti-PD-1 resistance in non-small cell lung cancer.
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Author Correction: Neoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial.
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Deep Learning-Based H-Score Quantification of Immunohistochemistry-Stained Images.
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Nectin-4 expression in a subset of cutaneous adnexal carcinomas: A potential target for therapy with enfortumab vedotin.
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LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells.
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Tumor- and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes.
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Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial.
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An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
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Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept.
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Atezolizumab plus bevacizumab in advanced Merkel cell carcinoma: A prospective study.
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Differential Upregulation of Th1/Th17-Associated Proteins and PD-L1 in Granulomatous Mycosis Fungoides.
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Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
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Cancer biomarkers: Emerging trends and clinical implications for personalized treatment.
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Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights.
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