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Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
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Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer. Nat Med. 2018 07; 24(7):1047-1057.
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PubMed
subject areas
Animals
Biosynthetic Pathways
Cell Line, Tumor
Cell Respiration
DNA Helicases
Energy Metabolism
Female
Genetic Engineering
Humans
Lung Neoplasms
Mice, Nude
Mitochondria
Mutation
Nuclear Proteins
Oxidative Phosphorylation
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Stress, Physiological
Transcription Factors
Xenograft Model Antitumor Assays
authors with profiles
BINGLIANG FANG
IGNACIO IVAN WISTUBA
KUNAL RAI
FLORIAN MULLER
YONATHAN LISSANU DERIBE