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WISTUBA, IGNACIO IVAN
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Item TypeName
Academic Article Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway.
Academic Article Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer.
Academic Article Mismatch repair gene expression and genetic instability in testicular germ cell tumor.
Academic Article Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects.
Academic Article Mortality in the randomized, controlled lung intergroup trial of isotretinoin.
Academic Article Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer.
Academic Article A phase II study of gefitinib for aggressive cutaneous squamous cell carcinoma of the head and neck.
Academic Article ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.
Academic Article Fibulin-2 is a driver of malignant progression in lung adenocarcinoma.
Academic Article Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers.
Academic Article Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer.
Academic Article Smoking-related genomic signatures in non-small cell lung cancer.
Academic Article Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model.
Academic Article Somatic mutations affect key pathways in lung adenocarcinoma.
Academic Article Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma.
Academic Article Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.
Academic Article Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions.
Academic Article TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
Academic Article Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor ?2 expression.
Academic Article Activating enhancer-binding protein-2? nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection.
Academic Article G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer.
Academic Article Characterizing the cancer genome in lung adenocarcinoma.
Academic Article Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.
Academic Article Phase II trials of imatinib mesylate and docetaxel in patients with metastatic non-small cell lung cancer and head and neck squamous cell carcinoma.
Academic Article MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression.
Concept Endodermal Sinus Tumor
Concept Colorectal Neoplasms, Hereditary Nonpolyposis
Concept Biliary Tract Neoplasms
Concept Thyroid Neoplasms
Concept Bronchial Neoplasms
Concept Tracheal Neoplasms
Concept Neuroendocrine Tumors
Concept Pleural Neoplasms
Concept Neoplasms, Multiple Primary
Concept Muscle Neoplasms
Concept Duodenal Neoplasms
Concept Tumor Burden
Concept Esophageal Neoplasms
Concept Brain Neoplasms
Concept Lung Neoplasms
Concept Uterine Neoplasms
Concept Neoplasms, Germ Cell and Embryonal
Concept Tumor Suppressor Protein p53
Concept Prostatic Neoplasms
Concept Neoplasm Metastasis
Concept Genes, Tumor Suppressor
Concept Adrenal Gland Neoplasms
Concept Hematologic Neoplasms
Concept Mammary Neoplasms, Animal
Concept Biomarkers, Tumor
Concept Antigens, Neoplasm
Concept Gallbladder Neoplasms
Concept Antigens, Viral, Tumor
Concept Ovarian Neoplasms
Concept Thymus Neoplasms
Concept Antigens, Tumor-Associated, Carbohydrate
Concept Sweat Gland Neoplasms
Concept Meningeal Neoplasms
Concept DNA, Neoplasm
Concept Tumor Necrosis Factor Receptor Superfamily, Member 9
Concept Mediastinal Neoplasms
Concept Common Bile Duct Neoplasms
Concept Urinary Bladder Neoplasms
Concept Appendiceal Neoplasms
Concept Neoplasms, Experimental
Concept Neoplasms, Second Primary
Concept Colorectal Neoplasms
Concept Salivary Gland Neoplasms
Concept Pancreatic Neoplasms
Concept Multiple Endocrine Neoplasia Type 2b
Concept Neoplasm Proteins
Concept Neoplasm Staging
Concept Neoplasms, Radiation-Induced
Concept Tumor Escape
Concept Kidney Neoplasms
Concept Vulvar Neoplasms
Concept Drug Resistance, Neoplasm
Concept Neoplasm Transplantation
Concept Carcinoid Tumor
Concept Mouth Neoplasms
Concept Breast Neoplasms
Concept Stomach Neoplasms
Concept Bone Neoplasms
Concept Tumor Stem Cell Assay
Concept Tumor Cells, Cultured
Concept Phyllodes Tumor
Concept Head and Neck Neoplasms
Concept Lymphocytes, Tumor-Infiltrating
Concept Bile Duct Neoplasms
Concept Sebaceous Gland Neoplasms
Concept Neoplasms, Glandular and Epithelial
Concept Tumor Necrosis Factor-alpha
Concept Multiple Endocrine Neoplasia Type 2a
Concept Von Hippel-Lindau Tumor Suppressor Protein
Concept Neoplasms
Concept Skin Neoplasms
Concept Receptors, Tumor Necrosis Factor
Concept Tongue Neoplasms
Concept Neoplasms, Adnexal and Skin Appendage
Concept Colonic Neoplasms
Concept Cell Line, Tumor
Concept Tumor Suppressor Proteins
Concept Neuroectodermal Tumors, Primitive
Concept Neoplasm Recurrence, Local
Concept Neoplasms, Squamous Cell
Concept Splenic Neoplasms
Concept Peritoneal Neoplasms
Concept Genes, Neoplasm
Concept RNA, Neoplasm
Concept Liver Neoplasms
Concept Uterine Cervical Neoplasms
Concept Soft Tissue Neoplasms
Concept Tumor Virus Infections
Concept Neoplasm Invasiveness
Concept Testicular Neoplasms
Concept Endometrial Neoplasms
Academic Article SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines.
Academic Article Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells.
Academic Article Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR-?) is associated with PDGFRB gene copy number gain in sarcomatoid non-small-cell lung cancer.
Academic Article Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.
Academic Article Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors.
Academic Article c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.
Academic Article Extrahepatic bile duct adenocarcinoma: patients at high-risk for local recurrence treated with surgery and adjuvant chemoradiation have an equivalent overall survival to patients with standard-risk treated with surgery alone.
Academic Article ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.
Academic Article Epithelial-to-mesenchymal transition in the development and progression of adenocarcinoma and squamous cell carcinoma of the lung.
Academic Article Primary oncocytic adenocarcinomas of the lung: a clinicopathologic, immunohistochemical, and molecular biologic analysis of 16 cases.
Academic Article Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.
Academic Article Histologic features of low- and intermediate-grade neuroendocrine carcinoma (typical and atypical carcinoid tumors) of the lung.
Academic Article Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.
Academic Article Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis.
Academic Article Sox10-positive sustentacular cells in neuroendocrine carcinoma of the lung.
Academic Article Oncocytic neuroendocrine tumors of the lung: histopathologic spectrum and immunohistochemical analysis of 15 cases.
Academic Article Using the mitosis-specific marker anti-phosphohistone H3 to assess mitosis in pulmonary neuroendocrine carcinomas.
Academic Article Histologic patterns and molecular characteristics of lung adenocarcinoma associated with clinical outcome.
Academic Article Clinicopathological and immunohistochemical analysis of spindle-cell carcinoid tumour of the lung.
Academic Article Thymomas I: a clinicopathologic correlation of 250 cases with emphasis on the World Health Organization schema.
Academic Article HER family receptor and ligand status in thymic carcinoma.
Academic Article Differential expression of somatostatin receptors 1-5 in neuroendocrine carcinoma of the lung.
Academic Article Molecular aspects of thymic carcinoma.
Academic Article Comparative immunohistochemical analysis of pulmonary and thymic neuroendocrine carcinomas using PAX8 and TTF-1.
Academic Article Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma.
Academic Article EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma.
Academic Article Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer.
Academic Article Thymic neuroendocrine tumors (paraganglioma and carcinoid tumors): a comparative immunohistochemical study of 46 cases.
Academic Article Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing.
Academic Article Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers.
Academic Article Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma.
Academic Article [Gallbladder cancer: immunohistochemical expression of CA-19-9, epithelial membrane antigen, dupan-2 and carcinoembryonic antigen].
Academic Article Eosinophilic globules in pigmented spindle cell nevus.
Academic Article [Advanced stomach neoplasms: expression of the fixation index of bromodeoxyuridine in vivo].
Academic Article [Association of gallbladder and Vater's ampulla neoplasms. Report of a case].
Academic Article [Gallbladder pathology in Temuco, IX Region].
Academic Article [Gallbladder cancer in the IX Region of Chile. Impact of the anatomopathological study of 474 cases].
Academic Article [Breast cancer and flow cytometry: comparative study of DNA ploidy pattern with clinicopathological parameters].
Academic Article [Cervix uteri cancer: determination of DNA content by means of cytophotometry].
Academic Article Loss of heterozygosity and microsatellite alterations in p53 and RB genes in adenoid cystic carcinoma of the salivary glands.
Academic Article Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: association with human papillomavirus type.
Academic Article Gallbladder adenomas have molecular abnormalities different from those present in gallbladder carcinomas.
Academic Article Genetic changes in the spectrum of neuroendocrine lung tumors.
Academic Article Comparison of features of human lung cancer cell lines and their corresponding tumors.
Academic Article Comparison of molecular changes in cervical intraepithelial neoplasia in HIV-positive and HIV-indeterminate subjects.
Academic Article Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer.
Academic Article Molecular abnormalities associated with secretory carcinomas of the breast.
Academic Article Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines.
Academic Article Pathogenesis of non-AIDS-defining cancers: a review.
Academic Article Molecular changes in the bronchial epithelium of patients with small cell lung cancer.
Academic Article Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma.
Academic Article Consensus statements from the Second International Lung Cancer Molecular Biomarkers Workshop: a European strategy for developing lung cancer molecular diagnostics in high risk populations.
Academic Article High resolution chromosome 3p, 8p, 9q and 22q allelotyping analysis in the pathogenesis of gallbladder carcinoma.
Academic Article Identification of novel cellular targets in biliary tract cancers using global gene expression technology.
Academic Article Comparative analysis of loss of heterozygosity and microsatellite instability in adult and pediatric melanoma.
Academic Article EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.
Academic Article TP53 abnormalities are frequent and early events in the sequential pathogenesis of gallbladder carcinoma.
Academic Article High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.
Academic Article Application of a methylation gene panel by quantitative PCR for lung cancers.
Academic Article Epidermal growth factor receptor abnormalities in lung cancer. Pathogenetic and clinical implications.
Academic Article Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung cancer.
Academic Article Molecular pathogenesis of early-stage non-small cell lung cancer and a proposal for tissue banking to facilitate identification of new biomarkers.
Academic Article Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion.
Academic Article Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene.
Academic Article Germ-line and somatic presentations of the EGFR T790M mutation in lung cancer.
Academic Article HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy.
Academic Article Chromosomal deletions and progression of premalignant lesions: less is more.
Academic Article Amplification of chromosomal segment 4q12 in non-small cell lung cancer.
Academic Article Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells.
Academic Article The multidisciplinary approach to thymoma: combining molecular and clinical approaches.
Academic Article Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
Academic Article Methodological and practical challenges for personalized cancer therapies.
Academic Article Differential impacts of insulin-like growth factor-binding protein-3 (IGFBP-3) in epithelial IGF-induced lung cancer development.
Academic Article Cotargeting cyclin D1 starts a new chapter in lung cancer prevention and therapy.
Academic Article The BATTLE to personalize lung cancer prevention through reverse migration.
Academic Article Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer.
Academic Article The role of PKR/eIF2a signaling pathway in prognosis of non-small cell lung cancer.
Academic Article Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
Academic Article Field cancerization in non-small cell lung cancer: implications in disease pathogenesis.
Academic Article The BATTLE trial: personalizing therapy for lung cancer.
Academic Article Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.
Academic Article Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion.
Academic Article Diagnosis of lung cancer in small biopsies and cytology: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification.
Academic Article Prognostic value of LIPC in non-small cell lung carcinoma.
Academic Article Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.
Academic Article Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial.
Academic Article An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Academic Article An update on clinicopathological, immunohistochemical, and molecular profiles of colloid carcinoma of the lung.
Academic Article [2 rare cases of a presentation of endometrial cancer].
Academic Article [In situ and invasive cancer of the gallbladder: nucleolar organizer regions].
Academic Article [Stomach neoplasms in the IX Region of Chile: comparison of the anatomo-pathological study of lymph node emptying in 2 periods].
Academic Article [Inapparent cancer of the gallbladder].
Academic Article [The pathological findings in patients reoperated on for gallbladder cancer].
Academic Article Allele-specific mutations involved in the pathogenesis of endemic gallbladder carcinoma in Chile.
Academic Article Proliferating cell nuclear antigen in gallbladder carcinoma.
Academic Article [Stomach and gallbladder cancer. Analysis of cell cycle phases by means of flow cytometry].
Academic Article [Determination of DNA content by means of cytophotometry. Technical and methodological considerations and its application in tumor pathology].
Academic Article DNA content in gallbladder carcinoma: a flow cytometric study of 96 cases.
Academic Article p53 protein overexpression in gallbladder carcinoma and its precursor lesions: an immunohistochemical study.
Academic Article [Epidermoid carcinoma of the cervix uteri: molecular abnormalities of p53 and rb genes].
Academic Article FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations.
Academic Article Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Academic Article Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene.
Academic Article Human papillomavirus type 16 is detected in transitional cell carcinomas and squamotransitional cell carcinomas of the cervix and endometrium.
Academic Article Mutation analysis of the PTEN/MMAC1 gene in lung cancer.
Academic Article Comparison of features of human breast cancer cell lines and their corresponding tumors.
Academic Article Deletions of chromosome 4 at multiple sites are frequent in malignant mesothelioma and small cell lung carcinoma.
Academic Article Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma.
Academic Article Enrichment of epithelial cells for molecular studies.
Academic Article K-ras and p53 mutations in the pathogenesis of classical and goblet cell carcinoids of the appendix.
Academic Article Multiple regions of chromosome 4 demonstrating allelic losses in breast carcinomas.
Academic Article Molecular identification of metastatic cancer to the skin using laser capture microdissection: a case report.
Academic Article Genome-wide allelotyping analysis reveals multiple sites of allelic loss in gallbladder carcinoma.
Academic Article High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss.
Academic Article Microdissection and the study of cancer pathways.
Academic Article BRAF mutation: a frequent event in benign, atypical, and malignant melanocytic lesions of the skin.
Academic Article Mitochondrial DNA mutation at the D310 (displacement loop) mononucleotide sequence in the pathogenesis of gallbladder carcinoma.
Academic Article The V599E BRAF mutation is uncommon in biliary tract cancers.
Academic Article Bronchioalveolar cell carcinoma: radiologic appearance and dilemmas in the assessment of response.
Academic Article Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence.
Academic Article Aberrant methylation of Reprimo in human malignancies.
Academic Article Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
Academic Article Frequent epigenetic inactivation of chromosome 3p candidate tumor suppressor genes in gallbladder carcinoma.
Academic Article Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry.
Academic Article Lung premalignancy induced by mutant B-Raf, what is thy fate? To senesce or not to senesce, that is the question.
Academic Article Molecular biology, genomics, and proteomics in bronchioloalveolar carcinoma.
Academic Article Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.
Academic Article Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer.
Academic Article Data driven semantic integration of translational lung cancer research at MDAnderson Cancer Center.
Academic Article Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas.
Academic Article Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.
Academic Article Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer.
Academic Article Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma.
Academic Article Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system.
Academic Article miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1.
Academic Article Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer.
Academic Article Exponential decay nonlinear regression analysis of patient survival curves: preliminary assessment in non-small cell lung cancer.
Academic Article Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation.
Academic Article Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
Academic Article Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence.
Academic Article International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Academic Article Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells.
Academic Article Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance.
Academic Article Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients.
Academic Article Pulmonary adenocarcinoma: a renewed entity in 2011.
Academic Article Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis.
Academic Article Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters.
Academic Article New strategies in squamous cell carcinoma of the lung: identification of tumor drivers to personalize therapy.
Academic Article Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy.
Academic Article Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer.
Academic Article Tissue platinum concentration and tumor response in non-small-cell lung cancer.
Academic Article Diagnosis of lung adenocarcinoma in resected specimens: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification.
Academic Article Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
Academic Article Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Academic Article 19q13-ERCC1 gene copy number increase in non--small-cell lung cancer.
Academic Article DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-?-driven epithelial-mesenchymal transition.
Academic Article miR-93-directed downregulation of DAB2 defines a novel oncogenic pathway in lung cancer.
Academic Article Identification of a subset of human non-small cell lung cancer patients with high PI3K? and low PTEN expression, more prevalent in squamous cell carcinoma.
Academic Article Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer.
Academic Article Phase I trial of cisplatin, pemetrexed, and imatinib mesylate in chemonaive patients with unresectable malignant pleural mesothelioma.
Academic Article CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.
Academic Article [Gastric cancer: epidermal growth factor and epidermal growth factor receptor].
Academic Article [Neoplasms of Vater's papilla: study of nucleolar organizer regions].
Academic Article Gallbladder cancer in Chile. A report on 54 potentially resectable tumors.
Academic Article [Immunohistochemical expression of the carcinoembryonic antigen in gallbladder cancer].
Academic Article [Nucleolus organizer regions and ploidy pattern of DNA in stomach neoplasms].
Academic Article [Gallbladder cancer: anatomic and anatomo-pathologic considerations].
Academic Article [Laparoscopic cholecystectomy makes difficult the analysis of gallbladder mucosa. Morphometric study].
Academic Article [Immunohistochemical expression of epidermal growth factor receptor (EGFR) in epidermoid carcinoma of the cervix uteri and its precursor lesions].
Academic Article [Gallbladder carcinoma: expression of the c-myc and ras-p-21 oncogene products].
Academic Article Gallbladder cancer in patients less than 40 years old.
Academic Article Analysis of the FHIT gene and FRA3B region in sporadic breast cancer, preneoplastic lesions, and familial breast cancer probands.
Academic Article DNA analysis at p53 locus in carcinomas arising from pleomorphic adenomas of salivary glands: comparison of molecular study and p53 immunostaining.
Academic Article Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.
Academic Article Precursors to pulmonary neoplasia.
Academic Article Molecular abnormalities associated with endocrine tumors of the uterine cervix.
Academic Article Loss of heterozygosity at 3p in benign lesions preceding invasive breast cancer.
Academic Article Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer.
Academic Article Genetic changes during the multistage pathogenesis of human papillomavirus positive and negative vulvar carcinomas.
Academic Article Use of archival fine-needle aspirates for the allelotyping of tumors.
Academic Article Presence of simian virus 40 sequences in malignant mesotheliomas and mesothelial cell proliferations.
Academic Article High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.
Academic Article Molecular analysis of synchronous and metachronous tumors of the lung: impact on management and prognosis.
Academic Article Clonality of combined tumors.
Academic Article Distinct K-ras mutation pattern characterizes signet ring cell colorectal carcinoma.
Academic Article Progression of gene hypermethylation in gallstone disease leading to gallbladder cancer.
Academic Article Nuclear morphometry as a biomarker for bronchial intraepithelial neoplasia: correlation with genetic damage and cancer development.
Academic Article Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.
Academic Article Cystic bronchioloalveolar cell carcinoma.
Academic Article Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
Academic Article Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions.
Academic Article Genetics of preneoplasia: lessons from lung cancer.
Academic Article Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
Academic Article KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer.
Academic Article A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer.
Academic Article Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensional organotypic air-liquid interface method.
Academic Article The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer.
Academic Article Lung cancer preneoplasia.
Academic Article Mismatch repair expression in testicular cancer predicts recurrence and survival.
Academic Article Molecular pathology of thymic epithelial neoplasms.
Academic Article PIK3CA mutations and copy number gains in human lung cancers.
Academic Article Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas.
Academic Article HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors.
Academic Article Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation.
Academic Article Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development.
Academic Article Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.
Academic Article EphA2 in the early pathogenesis and progression of non-small cell lung cancer.
Academic Article Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions.
Academic Article Biological activity of celecoxib in the bronchial epithelium of current and former smokers.
Academic Article SSTR2-based reporters for assessing gene transfer into non-small cell lung cancer: evaluation using an intrathoracic mouse model.
Academic Article Phase II study of dasatinib in patients with advanced non-small-cell lung cancer.
Academic Article Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers.
Academic Article Bronchioloalveolar carcinoma: a translational perspective.
Academic Article A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis.
Academic Article Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer.
Academic Article The impact of phosphorylated AMP-activated protein kinase expression on lung cancer survival.
Academic Article Evolving concepts in lung carcinogenesis.
Academic Article STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma.
Academic Article Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development.
Academic Article miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers.
Academic Article Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study.
Academic Article Prognostic impact of vitamin B6 metabolism in lung cancer.
Academic Article Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trial.
Academic Article An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
Academic Article CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.
Academic Article Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma.
Academic Article Computed tomography RECIST assessment of histopathologic response and prediction of survival in patients with resectable non-small-cell lung cancer after neoadjuvant chemotherapy.
Academic Article A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients.
Academic Article RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.
Academic Article Prognostic significance of combinations of RNA-dependent protein kinase and EphA2 biomarkers for NSCLC.
Academic Article Feasibility of image-guided transthoracic core-needle biopsy in the BATTLE lung trial.
Academic Article Uncommon epidermal growth factor receptor mutations in non-small cell lung cancer and their mechanisms of EGFR tyrosine kinase inhibitors sensitivity and resistance.
Academic Article Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial.
Academic Article DeMix: deconvolution for mixed cancer transcriptomes using raw measured data.
Academic Article The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors.
Academic Article RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner.
Academic Article Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?
Academic Article Prediction of survival in resected non-small cell lung cancer using a protein expression-based risk model: implications for personalized chemoprevention and therapy.
Academic Article TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients.
Academic Article Membrane carbonic anhydrase IX expression and relapse risk in resected stage I-II non-small-cell lung cancer.
Academic Article [Immunohistochemical demonstration of pepsinogens I and II in the gallbladder].
Academic Article [Expression of p29, estrogen receptor related protein in primary breast carcinoma. Methodological, anatomoclinical, and DNA content analysis].
Academic Article [Determination of DNA content using cytophotometry in nuclear suspension conserved for prolonged periods (preliminary study)].
Academic Article [Mutagen extraction from bile of patients with inflammatory biliary pathology: Ames test using blue rayon].
Academic Article [Epithelial lesions associated with gallbladder carcinoma. A methodical study of 32 cases].
Academic Article [Proliferating cell nuclear antigen in cervical cancer and precursor lesions].
Academic Article Comparison of molecular changes in lung cancers in HIV-positive and HIV-indeterminate subjects.
Academic Article DNA analysis at p53 locus in adenoid cystic carcinoma: comparison of molecular study and p53 immunostaining.
Academic Article Allelic losses at chromosome 3p are seen in human papilloma virus 16 associated transitional cell carcinoma of the cervix.
Academic Article Genetic abnormalities involved in the pathogenesis of gallbladder carcinoma.
Academic Article Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome.
Academic Article Molecular changes in second primary lung and breast cancers after therapy for Hodgkin's disease.
Academic Article Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
Academic Article Microsatellite analysis of synchronous and metachronous tumors: a tool for double primary tumor and metastasis assessment.
Academic Article Detection of lymphatic micrometastases in patients with stages I and II colorectal cancer: impact on five-year survival.
Academic Article Gallbladder cancer: lessons from a rare tumour.
Academic Article Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
Academic Article Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma.
Academic Article High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Academic Article Bronchioloalveolar carcinoma and lung adenocarcinoma: the clinical importance and research relevance of the 2004 World Health Organization pathologic criteria.
Academic Article Cyclic AMP response element-binding protein overexpression: a feature associated with negative prognosis in never smokers with non-small cell lung cancer.
Academic Article Elevated phospho-S6 expression is associated with metastasis in adenocarcinoma of the lung.
Academic Article Integration of molecular profiling into the lung cancer clinic.
Academic Article Prognostic significance of RNA-dependent protein kinase on non-small cell lung cancer patients.
Academic Article Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy.
Academic Article Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts.
Academic Article Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion.
Academic Article Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Academic Article Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.
Academic Article Personalizing lung cancer prevention through a reverse migration strategy.
Academic Article Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling.
Academic Article ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer.
Academic Article A reevaluation of CD22 expression in human lung cancer.
Academic Article Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer.
Academic Article Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma.
Academic Article [Nucleolar organizer regions in uterine cervical cancer and its precursor epithelial lesions].
Academic Article Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma.
Academic Article Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis.
Academic Article Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.
Academic Article Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis.
Academic Article [Atypical presentation of a colorectal carcinoma].
Academic Article Histologic evaluation of bronchial squamous lesions: any role in lung cancer risk assessment?
Academic Article [Pathogenic role of PTEN tumor suppressor gene in ovarian cancer associated to endometriosis].
Academic Article Aromatase expression predicts survival in women with early-stage non small cell lung cancer.
Academic Article A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras.
Academic Article Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer.
Academic Article Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma.
Academic Article High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation.
Academic Article Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.
Academic Article NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.
Academic Article The evolving genomic classification of lung cancer.
Academic Article Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs.
Academic Article Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma.
Academic Article Presence of simian virus 40 sequences in malignant pleural, peritoneal and noninvasive mesotheliomas.
Academic Article Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors.
Academic Article Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications.
Academic Article Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer.
Academic Article VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy.
Academic Article Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer.
Academic Article Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway.
Academic Article Vandetanib and indwelling pleural catheter for non-small-cell lung cancer with recurrent malignant pleural effusion.
Academic Article Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma.
Academic Article A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.
Academic Article Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.
Academic Article Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples.
Academic Article Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study.
Academic Article A phase I/II study combining erlotinib and dasatinib for non-small cell lung cancer.
Academic Article Current concepts on the molecular pathology of non-small cell lung carcinoma.
Academic Article ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.
Academic Article Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.
Academic Article Validation of a molecular and pathological model for five-year mortality risk in patients with early stage lung adenocarcinoma.
Academic Article Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition.
Academic Article Genetic mutation of p53 and suppression of the miR-17~92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling.
Academic Article Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Academic Article Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer.
Academic Article Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience.
Academic Article Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival.
Academic Article RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells.
Academic Article RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer.
Academic Article An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.
Academic Article Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer.
Academic Article Adding Erlotinib to Chemoradiation Improves Overall Survival but Not Progression-Free Survival in Stage III Non-Small Cell Lung Cancer.
Academic Article Regulation of AURKC expression by CpG island methylation in human cancer cells.
Academic Article Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer.
Academic Article Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment.
Academic Article Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.
Academic Article Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?
Academic Article The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification.
Academic Article Pleuropulmonary Meningothelial Proliferations: Evidence for a Common Histogenesis.
Academic Article Molecular Testing for Treatment of Metastatic Non-Small Cell Lung Cancer: How to Implement Evidence-Based Recommendations.
Academic Article LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells.
Academic Article From Uniplex to Multiplex Molecular Profiling in Advanced Non-Small Cell Lung Carcinoma.
Academic Article Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations.
Academic Article NRF2 regulates serine biosynthesis in non-small cell lung cancer.
Academic Article Image-Guided Biopsy in the Era of Personalized Cancer Care: Proceedings from the Society of Interventional Radiology Research Consensus Panel.
Academic Article ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis.
Academic Article Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway.
Academic Article Multiplatform-based molecular subtypes of non-small-cell lung cancer.
Academic Article Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties.
Academic Article Regulation of AURKC expression by CpG island methylation in human cancer cells
Academic Article Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors
Academic Article Corrigendum to "PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer" [Neoplasia 18 (2016) 282-293]
Academic Article Cancer-associated fibroblasts induce a collagen cross-link switch in tumor stroma
Academic Article An integrated molecular analysis of lung adenocarcinomas identifies potential therapeutic targets among TTF1-negative tumors, including DNA Repair Proteins and Nrf2
Academic Article STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T-cell activity in the lung tumor microenvironment
Academic Article Molecular changes in cervical endocrine tumors
Academic Article Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples
Academic Article Primary Mediastinal Yolk Sac Tumors
Academic Article The 2015 World Health Organization Classification of Lung Tumors
Academic Article Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma
Academic Article Image analysis-based assessment of PD-L1 and tumor-associated immune cells density supports distinct intratumoral microenvironment groups in non-small cell lung carcinoma patients
Academic Article Molecular changes in cervical endocrine tumors
Academic Article IL6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras-mutant lung cancer
Academic Article Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade
Academic Article Sarcomatoid Renal Cell Carcinoma Has a Distinct Molecular Pathogenesis, Driver Mutation Profile, and Transcriptional Landscape.
Academic Article Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis.
Academic Article Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome.
Academic Article Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.
Academic Article RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer.
Academic Article Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGF?RIII-p38MAPK-pS249/T252RB Pathway.
Academic Article The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.
Academic Article Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis.
Academic Article Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.
Academic Article Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.
Academic Article LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells.
Academic Article A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition.
Academic Article Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial.
Academic Article Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.
Academic Article Optimizing the DNA yield for molecular analysis from cytologic preparations.
Academic Article Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients With Lung Adenocarcinoma.
Academic Article STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
Academic Article Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations.
Academic Article Minimally invasive genomic and transcriptomic profiling of visceral cancers by next-generation sequencing of circulating exosomes.
Academic Article Validation of SCT Methylation as a Hallmark Biomarker for Lung Cancers.
Academic Article Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases.
Academic Article Early Events in the Molecular Pathogenesis of Lung Cancer.
Academic Article KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib.
Academic Article Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma.
Academic Article Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma.
Academic Article The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer: Status in 2016.
Academic Article Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Academic Article Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity.
Academic Article Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations.
Academic Article ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.
Academic Article Spindle cell and pleomorphic ("sarcomatoid") carcinomas of the lung: an immunohistochemical analysis of 86 cases.
Academic Article Primary Mediastinal Yolk Sac Tumors: An Immunohistochemical Analysis of 14 Cases.
Academic Article IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.
Academic Article An Expression Signature as an Aid to the Histologic Classification of Non-Small Cell Lung Cancer.
Academic Article Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer.
Academic Article Image Analysis-based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-small Cell Lung Carcinoma Patients.
Academic Article Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Academic Article PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis.
Academic Article Comprehensive Computational Pathological Image Analysis Predicts Lung Cancer Prognosis.
Academic Article The ISG15-specific protease USP18 regulates stability of PTEN.
Academic Article Comprehensive evaluation of published gene expression prognostic signatures for biomarker-based lung cancer clinical studies.
Academic Article High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients.
Academic Article Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer.
Academic Article Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function.
Academic Article XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Academic Article Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up.
Academic Article Genomic heterogeneity of multiple synchronous lung cancer.
Academic Article Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers.
Academic Article Lung Cancer Biomarkers.
Academic Article Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.
Academic Article A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer.
Academic Article Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer.
Academic Article DNA methylation intratumor heterogeneity in localized lung adenocarcinomas.
Academic Article Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.
Academic Article CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Academic Article Phase I Trial of Cediranib in Combination with Cisplatin and Pemetrexed in Chemonaive Patients with Unresectable Malignant Pleural Mesothelioma (SWOG S0905).
Academic Article JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non-Small Cell Lung Cancer.
Academic Article Expression of PD-1 and PD-L1 in thymic epithelial neoplasms.
Academic Article VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer.
Academic Article GLI1 Blockade Potentiates the Antitumor Activity of PI3K Antagonists in Lung Squamous Cell Carcinoma.
Academic Article Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.
Academic Article Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer.
Academic Article Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma.
Academic Article Study of Preanalytic and Analytic Variables for Clinical Next-Generation Sequencing of Circulating Cell-Free Nucleic Acid.
Academic Article The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.
Academic Article TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.
Academic Article Update on EGFR Mutational Testing and the Potential of Noninvasive Liquid Biopsy in Non-Small-cell Lung Cancer.
Academic Article Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.
Academic Article Novel enriched pathways in superficial malignant peripheral nerve sheath tumours and spindle/desmoplastic melanomas.
Academic Article Interobserver Variation among Pathologists and Refinement of Criteria in Distinguishing Separate Primary Tumors from Intrapulmonary Metastases in Lung.
Academic Article Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol.
Academic Article Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with ?-blockers.
Academic Article Versatile ion S5XL sequencer for targeted next generation sequencing of solid tumors in a clinical laboratory.
Academic Article A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling.
Academic Article Programmed cell death ligand 1 and tumor-infiltrating lymphocyte status in patients with renal cell carcinoma and sarcomatoid dedifferentiation.
Academic Article Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemotherapy.
Academic Article Metastasis of cancer: when and how?
Academic Article Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues.
Academic Article Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Academic Article Serum MicroRNA-150 Predicts Prognosis for Early-Stage Non-Small Cell Lung Cancer and Promotes Tumor Cell Proliferation by Targeting Tumor Suppressor Gene SRCIN1.
Academic Article Programmed Death Cell Ligand 1 (PD-L1) Is Associated With Survival in Stage I Non-Small Cell Lung Cancer.
Academic Article Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer.
Academic Article Biomarker-Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma.
Academic Article Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma.
Academic Article Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer.
Academic Article Salvaging the supernatant: next generation cytopathology for solid tumor mutation profiling.
Academic Article Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors.
Academic Article Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors.
Academic Article Major pathologic response and RAD51 predict survival in lung cancer patients receiving neoadjuvant chemotherapy.
Academic Article Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.
Academic Article Induction Cisplatin Docetaxel Followed by Surgery and Erlotinib in Non-Small Cell Lung Cancer.
Academic Article The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations-The Lung Cancer Mutation Consortium (LCMC2).
Academic Article Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer.
Academic Article Multiregion gene expression profiling reveals heterogeneity in molecular subtypes and immunotherapy response signatures in lung cancer.
Academic Article Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease.
Academic Article CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.
Academic Article A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms.
Academic Article Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.
Academic Article Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer.
Academic Article Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial.
Academic Article Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer.
Academic Article Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident.
Academic Article Liquid Biopsy for Advanced Non-Small Cell Lung?Cancer (NSCLC): A Statement Paper from the?IASLC.
Academic Article Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
Academic Article The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer.
Academic Article HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress.
Academic Article STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
Academic Article Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.
Academic Article Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
Academic Article Validation of the 12-gene Predictive Signature for Adjuvant Chemotherapy Response in Lung Cancer.
Academic Article Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition.
Academic Article Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.
Academic Article Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration.
Academic Article 5 protein-based signature for resectable lung squamous cell carcinoma improves the prognostic performance of the TNM staging.
Academic Article PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.
Academic Article Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.
Academic Article Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.
Academic Article LCE: an open web portal to explore gene expression and clinical associations in lung cancer.
Academic Article METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
Academic Article Centrifuged supernatants from FNA provide a liquid biopsy option for clinical next-generation sequencing of thyroid nodules.
Academic Article Rational "Error Elimination" Approach to Evaluating Molecular Barcoded Next-Generation Sequencing Data Identifies Low-Frequency Mutations in Hematologic Malignancies.
Academic Article B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density.
Academic Article ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.
Academic Article Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
Academic Article PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer.
Academic Article State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues.
Academic Article Gene expression profiling of lichenoid dermatitis immune-related adverse event from immune checkpoint inhibitors reveals increased CD14+ and CD16+ monocytes driving an innate immune response.
Academic Article Liquid biopsy assay for lung carcinoma using centrifuged supernatants from fine-needle aspiration specimens.
Academic Article Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer.
Academic Article Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung.
Academic Article A novel protein-based prognostic signature improves risk stratification to guide clinical management in early-stage lung adenocarcinoma patients.
Academic Article Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.
Academic Article Development and Validation of a Pathology Image Analysis-based Predictive Model for Lung Adenocarcinoma Prognosis - A Multi-cohort Study.
Concept Circulating Tumor DNA
Concept Tumor Microenvironment
Concept Neoplasm Grading
Concept Triple Negative Breast Neoplasms
Academic Article YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
Academic Article Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer.
Academic Article Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma.
Academic Article Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer.
Academic Article Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer.
Academic Article Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma.
Academic Article Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer.
Academic Article Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.
Academic Article Characterization and Comparison of GITR Expression in Solid Tumors.
Academic Article Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy.
Academic Article A proposal for pathologic processing of breast implant capsules in patients with suspected breast implant anaplastic large cell lymphoma.
Academic Article Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Na?ve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905).
Academic Article Development and Application of Duplex Sequencing Strategy for Cell-Free DNA-Based Longitudinal Monitoring of Stage IV Colorectal Cancer.
Academic Article Non-invasive genotyping of metastatic colorectal cancer using circulating cell free DNA.
Academic Article Oncogenic enhancer of zeste homolog 2 is an actionable target in patients with non-small cell lung cancer.
Academic Article Multiplex Immunofluorescence Assays.
Academic Article Lymphovascular Invasion Is Associated With Mutational Burden and PD-L1 in Resected Lung Cancer.
Academic Article Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
Academic Article Nicotinic acetylcholine receptor expression in human airway correlates with lung function.
Academic Article Expression of Epithelial-Mesenchymal Transition Markers in Treated Pancreatic Ductal Adenocarcinoma.
Academic Article The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma.
Academic Article Mesonephric-like Carcinoma of the Endometrium: A Subset of Endometrial Carcinoma With an Aggressive Behavior.
Academic Article Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation.
Academic Article Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC.
Academic Article ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network.
Academic Article High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer.
Academic Article Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance.
Academic Article PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee.
Academic Article RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.
Academic Article Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer.
Academic Article Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy.
Academic Article IASLC Multidisciplinary Recommendations for Pathologic Assessment of Lung Cancer Resection Specimens After Neoadjuvant Therapy.
Academic Article Comprehensive T cell repertoire characterization of non-small cell lung cancer.
Academic Article New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
Academic Article STING Pathway Expression Identifies NSCLC With an Immune-Responsive Phenotype.
Academic Article A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non-Small Cell Lung Cancer.
Academic Article Agreement on Major Pathological Response in NSCLC Patients Receiving Neoadjuvant Chemotherapy.
Academic Article 18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer.
Academic Article Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors.
Academic Article T-Cell Repertoire in Combination with T-Cell Density Predicts Clinical Outcomes in Patients with Merkel Cell Carcinoma.
Academic Article Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort.
Academic Article Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.
Academic Article The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation.
Academic Article Programmed Death-Ligand 1 Heterogeneity and Its Impact on Benefit From Immune Checkpoint Inhibitors in NSCLC.
Academic Article LKB1/STK11 Expression in Lung Adenocarcinoma and Associations With Patterns of Recurrence.
Academic Article Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers: Results From a Retrospective Multicenter Cohort Study.
Academic Article An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.
Academic Article The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker: A Perspective from the International Association for the Study of Lung Cancer Pathology Committee.
Academic Article A Grading System for Invasive Pulmonary Adenocarcinoma: A Proposal From the International Association for the Study of Lung Cancer Pathology Committee.
Academic Article A Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma.
Academic Article Interplay between estrogen and Stat3/NF-?B-driven immunomodulation in lung cancer.
Academic Article Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa.
Academic Article Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development.
Academic Article Female Gender Predicts Augmented Immune Infiltration in Lung Adenocarcinoma.
Academic Article Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment.
Academic Article Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion.
Academic Article eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer.
Academic Article TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer.
Academic Article Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC.
Academic Article Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting.
Academic Article Sarcomatoid Mesothelioma: A CDKN2A molecular analysis of 53 cases with immunohistochemical correlation with BAP1.
Academic Article Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity.
Academic Article The value of interventional radiology in clinical trial teams: experience from the BATTLE lung cancer trials.
Academic Article Altered Regulation of HIF-1a in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype.
Academic Article Cross-Site Concordance Evaluation of Tumor DNA and RNA Sequencing Platforms for the CIMAC-CIDC Network.
Academic Article Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax.
Academic Article Pathologic Assessment of Lung Squamous Cell Carcinoma After Neoadjuvant Immunotherapy.
Academic Article Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.
Academic Article CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma.
Academic Article Network for Biomarker Immunoprofiling for Cancer Immunotherapy: Cancer Immune Monitoring and Analysis Centers and Cancer Immunologic Data Commons (CIMAC-CIDC).
Academic Article Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities.
Academic Article Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas.
Academic Article Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
Academic Article Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer.
Academic Article PD-L1 as a biomarker of response to immune-checkpoint inhibitors.
Academic Article PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer.
Academic Article Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).
Academic Article Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial.
Academic Article Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer.
Academic Article Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib?onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit.
Academic Article Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.
Academic Article Corrigendum to "PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer" [Neoplasia 18 (2016) 282-293].
Academic Article Challenges in Facing the Lung Cancer Epidemic and Treating Advanced Disease in Latin America.
Academic Article TMPRSS4: A Novel Tumor Prognostic Indicator for the Stratification of Stage IA Tumors and a Liquid Biopsy Biomarker for NSCLC Patients.
Academic Article Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues.
Academic Article The International Association for the Study of Lung Cancer Global Survey on Programmed Death-Ligand 1 Testing for NSCLC.
Academic Article Global analysis of shared T?cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery.
Academic Article Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer.
Academic Article Overexpression of CD73 in pancreatic ductal adenocarcinoma is associated with immunosuppressive tumor microenvironment and poor survival.
Academic Article CD8+ T cells inhibit metastasis and CXCL4 regulates its function.
Academic Article Pilot Clinical Trial of Perioperative Durvalumab and Tremelimumab in the Treatment of Resectable Colorectal Cancer Liver Metastases.
Academic Article Evaluation of Pathologic Response in Lymph Nodes of Patients With Lung Cancer Receiving Neoadjuvant Chemotherapy.
Academic Article Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity.
Academic Article Immuno-profiling and cellular spatial analysis using five immune oncology multiplex immunofluorescence panels for paraffin tumor tissue.
Academic Article Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors.
Academic Article Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing.
Academic Article Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features.
Academic Article Multiplex Immunofluorescence Tyramide Signal Amplification for Immune Cell Profiling of Paraffin-Embedded Tumor Tissues.
Academic Article The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
Academic Article Liquid Biopsy for Advanced NSCLC: A Consensus Statement From the International Association for the Study of Lung Cancer.
Academic Article Immune Phenotype and Response to Neoadjuvant Therapy in Triple-Negative Breast Cancer.
Academic Article Multiplex Tissue Imaging Harmonization: A Multicenter Experience from CIMAC-CIDC Immuno-Oncology Biomarkers Network.
Academic Article Efficacy, Safety, and Biomarker Analysis of Combined PD-L1 (Atezolizumab) and VEGF (Bevacizumab) Blockade in Advanced Malignant Peritoneal Mesothelioma.
Academic Article Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE) Study.
Academic Article Immune Profiling Mass Cytometry Assay Harmonization: Multicenter Experience from CIMAC-CIDC.
Academic Article A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers.
Academic Article Estrogen Promotes Resistance to Bevacizumab in Murine Models of NSCLC.
Academic Article Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial.
Academic Article Pretreatment Tissue TCR Repertoire Evenness Is Associated with Complete Pathologic Response in Patients with NSCLC Receiving Neoadjuvant Chemoimmunotherapy.
Academic Article Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer.
Academic Article Artificial intelligence strategy integrating morphologic and architectural biomarkers provides robust diagnostic accuracy for disease progression in chronic lymphocytic leukemia.
Academic Article SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas.
Academic Article The immunogenomic landscape of resected intrahepatic cholangiocarcinoma.
Academic Article NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis.
Academic Article Genomic Profiling of Lung Adenocarcinoma in Never-Smokers.
Academic Article Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer.
Academic Article The Combiome Hypothesis: Selecting Optimal Treatment for Cancer Patients.
Academic Article Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer.
Academic Article PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
Academic Article Effector memory cytotoxic CD3+/CD8+/CD45RO+ T cells are predictive of good survival and a lower risk of recurrence in triple-negative breast cancer.
Academic Article The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics.
Academic Article Surgical approach does not influence changes in circulating immune cell populations following lung cancer resection.
Academic Article Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes.
Academic Article ESMO expert consensus statements on the management of EGFR mutant non-small-cell lung cancer.
Academic Article SIRPa+ macrophages are increased in patients with FL who progress or relapse after frontline lenalidomide and rituximab.
Academic Article Expression of TRPS1 in phyllodes tumor and sarcoma of the breast.
Academic Article MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers.
Academic Article Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer.
Academic Article Assessment of Clinical Response Following Atezolizumab and Bevacizumab Treatment in Patients With Neuroendocrine Tumors: A Nonrandomized Clinical Trial.
Academic Article Distinct Immune Gene Programs Associated with Host Tumor Immunity, Neoadjuvant Chemotherapy, and Chemoimmunotherapy in Resectable NSCLC.
Academic Article AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T?cells.
Academic Article Diminished Immune Surveillance during Histologic Progression of Intraductal Papillary Mucinous Neoplasms Offers a Therapeutic Opportunity for Cancer Interception.
Academic Article Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma.
Academic Article Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma.
Academic Article Impact of Region-of-Interest Size on Immune Profiling Using Multiplex Immunofluorescence Tyramide Signal Amplification for Paraffin-Embedded Tumor Tissues.
Academic Article The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8+ cytotoxic T-cell response.
Academic Article Implementation of a Novel Web-Based Lesion Selection Tool to Improve Acquisition of Tumor Biopsy Specimens.
Academic Article Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk.
Academic Article Game of clones: Battles in the field of carcinogenesis.
Academic Article Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.
Academic Article Immunogenomic profiling of lung adenocarcinoma reveals poorly differentiated tumors are associated with an immunogenic tumor microenvironment.
Academic Article Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas: a single-centre phase 2 trial.
Academic Article The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma.
Academic Article Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer.
Academic Article Predictive Biomarkers for Immunotherapy in Lung Cancer: Perspective From the International Association for the Study of Lung Cancer Pathology Committee.
Academic Article Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non-small cell lung cancer.
Academic Article Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.
Academic Article Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
Academic Article A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response.
Academic Article Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures.
Academic Article Neoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial.
Academic Article Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer.
Academic Article Netie: inferring the evolution of neoantigen-T cell interactions in tumors.
Academic Article Phase II study of durvalumab (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
Academic Article Analysis of Immune Intratumor Heterogeneity Highlights Immunoregulatory and Coinhibitory Lymphocytes as Hallmarks of?Recurrence in Stage I Non-Small Cell Lung Cancer.
Academic Article Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.
Academic Article Extrauterine Mesonephric-like Carcinoma: A Comprehensive Single Institution Study of 33 Cases.
Academic Article Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer: The EXTEND Phase 2 Randomized Clinical Trial.
Academic Article Naproxen chemoprevention induces proliferation of cytotoxic lymphocytes in Lynch Syndrome colorectal mucosa.
Academic Article Immune cellular patterns of distribution affect outcomes of patients with non-small cell lung cancer.
Academic Article Phase II trial of neoadjuvant sitravatinib plus nivolumab in patients undergoing nephrectomy for locally advanced clear cell renal cell carcinoma.
Academic Article Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer.
Academic Article Predicting benefit from immune checkpoint inhibitors in patients with non-small-cell lung cancer by CT-based ensemble deep learning: a retrospective study.
Academic Article Pathologist-initiated reflex testing for biomarkers in non-small-cell lung cancer: expert consensus on the rationale and considerations for implementation.
Academic Article MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
Academic Article Quantitative multiplexed imaging technologies for single-cell analysis to assess predictive markers for immunotherapy in thoracic immuno-oncology: promises and challenges.
Academic Article EMT activates exocytotic Rabs to coordinate invasion and immunosuppression in lung cancer.
Academic Article Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma.
Academic Article Stereotactic ablative radiotherapy with or without immunotherapy for early-stage or isolated lung parenchymal recurrent node-negative non-small-cell lung cancer: an open-label, randomised, phase 2 trial.
Academic Article International Association for the Study of Lung Cancer Study of Reproducibility in Assessment of Pathologic Response in Resected Lung Cancers After Neoadjuvant Therapy.
Academic Article Genomic Staging of Multifocal Lung Squamous Cell Carcinomas Is Independent of the Comprehensive Morphologic Assessment.
Academic Article Autotaxin suppresses cytotoxic T cells via LPAR5 to promote anti-PD-1 resistance in non-small cell lung cancer.
Academic Article Pathomic Features Reveal Immune and Molecular Evolution From Lung Preneoplasia to Invasive Adenocarcinoma.
Academic Article A novel Bayesian model for assessing intratumor heterogeneity of tumor infiltrating leukocytes with multi-region gene expression sequencing.
Academic Article Nectin-4 expression in a subset of cutaneous adnexal carcinomas: A potential target for therapy with enfortumab vedotin.
Academic Article Exploration of cancer associated fibroblasts phenotypes in the tumor microenvironment of classical and pleomorphic Invasive Lobular Carcinoma.
Academic Article LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells.
Academic Article Intragenic EGFR::EGFR.E1E8 Fusion (EGFRvIII) in 4331 Solid Tumors.
Academic Article Tumor- and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes.
Academic Article Circulating microRNA Panel for Prediction of Recurrence and Survival in Early-Stage Lung Adenocarcinoma.
Academic Article An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
Academic Article eEF1A2 promotes PTEN-GSK3?-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer.
Academic Article Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept.
Academic Article Atezolizumab plus bevacizumab in advanced Merkel cell carcinoma: A prospective study.
Academic Article Differential Upregulation of Th1/Th17-Associated Proteins and PD-L1 in Granulomatous Mycosis Fungoides.
Academic Article Exploratory pilot study to characterize the immune landscapes of malignant pleural effusions and their corresponding primary tumors from patients with breast carcinoma and lung adenocarcinoma.
Academic Article Cancer biomarkers: Emerging trends and clinical implications for personalized treatment.
Academic Article Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights.
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