"Endodermal Sinus Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
| Descriptor ID |
D018240
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| MeSH Number(s) |
C04.557.465.510.350
|
| Concept/Terms |
Endodermal Sinus Tumor- Endodermal Sinus Tumor
- Endodermal Sinus Tumors
- Tumor, Endodermal Sinus
- Tumors, Endodermal Sinus
- Yolk Sac Tumor
- Tumor, Yolk Sac
- Tumors, Yolk Sac
- Yolk Sac Tumors
|
Below are MeSH descriptors whose meaning is more general than "Endodermal Sinus Tumor".
Below are MeSH descriptors whose meaning is more specific than "Endodermal Sinus Tumor".
This graph shows the total number of publications written about "Endodermal Sinus Tumor" by people in this website by year, and whether "Endodermal Sinus Tumor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endodermal Sinus Tumor" by people in Profiles.
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Oral extragonadal yolk sac tumor in a patient with Aicardi syndrome: putative origin and differential diagnosis. Hum Pathol. 2012 Jun; 43(6):939-42.
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The use of cytokeratin 7 and EMA in differentiating ovarian yolk sac tumors from endometrioid and clear cell carcinomas. Am J Surg Pathol. 2004 Nov; 28(11):1499-505.
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Germ cell tumors of the mediastinum. Pathol Res Pract. 1999; 195(8):583-7.
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Mediastinal yolk sac tumors. Am J Surg Pathol. 1999 Jan; 23(1):132-3.
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Germ cell tumors of the mediastinum and testis: a comparative immunohistochemical study of 120 cases. Hum Pathol. 1998 Jul; 29(7):737-42.
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Hepatoid yolk sac tumors of the mediastinum: a clinicopathologic and immunohistochemical study of four cases. Am J Surg Pathol. 1997 Oct; 21(10):1210-4.
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Yolk sac tumors of the mediastinum with prominent spindle cell features: a clinicopathologic study of three cases. Am J Surg Pathol. 1997 Oct; 21(10):1173-7.
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Primary germ cell tumors of the mediastinum: III. Yolk sac tumor, embryonal carcinoma, choriocarcinoma, and combined nonteratomatous germ cell tumors of the mediastinum--a clinicopathologic and immunohistochemical study of 64 cases. Cancer. 1997 Aug 15; 80(4):699-707.
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Mediastinal yolk sac tumors associated with prominent multilocular cystic changes of thymic epithelium: a clinicopathologic and immunohistochemical study of five cases. Mod Pathol. 1997 Aug; 10(8):800-3.