Neoplasms, Second Primary
"Neoplasms, Second Primary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
| Descriptor ID |
D016609
|
| MeSH Number(s) |
C04.692
|
| Concept/Terms |
Neoplasms, Second Primary- Neoplasms, Second Primary
- Neoplasm, Second Primary
- Second Primary Neoplasm
- Metachronous Second Primary Neoplasms
- Neoplasms, Metachronous
- Second Primary Neoplasms, Metachronous
- Second Malignancy
- Malignancies, Second
- Malignancy, Second
- Second Malignancies
- Second Neoplasm
- Neoplasm, Second
- Neoplasms, Second
- Second Neoplasms
- Second Primary Neoplasms
- Metachronous Neoplasms
- Metachronous Neoplasm
- Neoplasm, Metachronous
- Neoplasms, Metachronous Second Primary
Neoplasms, Therapy-Associated- Neoplasms, Therapy-Associated
- Neoplasm, Therapy-Associated
- Neoplasms, Therapy Associated
- Therapy-Associated Neoplasm
- Neoplasms, Treatment-Associated
- Neoplasm, Treatment-Associated
- Neoplasms, Treatment Associated
- Treatment-Associated Neoplasm
- Neoplasms, Treatment-Related
- Neoplasm, Treatment-Related
- Neoplasms, Treatment Related
- Treatment-Related Neoplasm
- Therapy-Related Neoplasms
- Therapy Related Neoplasms
- Treatment-Associated Neoplasms
- Treatment Associated Neoplasms
- Treatment-Related Neoplasms
- Treatment Related Neoplasms
- Neoplasms, Therapy-Related
- Neoplasm, Therapy-Related
- Neoplasms, Therapy Related
- Therapy-Related Neoplasm
- Therapy-Associated Neoplasms
- Therapy Associated Neoplasms
Therapy-Associated Cancer- Therapy-Associated Cancer
- Cancer, Therapy-Associated
- Cancers, Therapy-Associated
- Therapy Associated Cancer
- Therapy-Associated Cancers
- Therapy-Related Cancer
- Cancer, Therapy-Related
- Cancers, Therapy-Related
- Therapy Related Cancer
- Therapy-Related Cancers
- Treatment-Related Cancer
- Cancer, Treatment-Related
- Cancers, Treatment-Related
- Treatment Related Cancer
- Treatment-Related Cancers
- Treatment-Associated Cancer
- Cancer, Treatment-Associated
- Cancers, Treatment-Associated
- Treatment Associated Cancer
- Treatment-Associated Cancers
Cancer, Second Primary- Cancer, Second Primary
- Cancers, Second Primary
- Second Primary Cancer
- Second Primary Cancers
- Second Cancer
- Cancer, Second
- Cancers, Second
- Second Cancers
|
Below are MeSH descriptors whose meaning is more general than "Neoplasms, Second Primary".
Below are MeSH descriptors whose meaning is more specific than "Neoplasms, Second Primary".
This graph shows the total number of publications written about "Neoplasms, Second Primary" by people in this website by year, and whether "Neoplasms, Second Primary" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 3 | 0 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 2 | 4 |
| 2005 | 3 | 0 | 3 |
| 2006 | 1 | 0 | 1 |
| 2008 | 3 | 0 | 3 |
| 2009 | 4 | 0 | 4 |
| 2010 | 4 | 0 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 6 | 1 | 7 |
| 2013 | 5 | 1 | 6 |
| 2014 | 3 | 0 | 3 |
| 2015 | 3 | 1 | 4 |
| 2016 | 4 | 1 | 5 |
| 2017 | 4 | 1 | 5 |
| 2018 | 2 | 1 | 3 |
| 2019 | 6 | 3 | 9 |
| 2020 | 2 | 2 | 4 |
| 2021 | 6 | 1 | 7 |
| 2022 | 5 | 0 | 5 |
| 2023 | 4 | 0 | 4 |
| 2024 | 5 | 1 | 6 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Neoplasms, Second Primary" by people in Profiles.
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Germline Pathogenic/Likely Pathogenic Mutations and Subsequent Neoplasms Among Childhood Cancer Survivors: A Report From the Children's Oncology Group ALTE03N1 Study. J Clin Oncol. 2025 Sep 20; 43(27):3011-3020.
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Contributions of cancer treatment and genetic predisposition to risk of subsequent neoplasms in long-term survivors of childhood cancer: a report from the St Jude Lifetime Cohort and the Childhood Cancer Survivor Study. Lancet Oncol. 2025 Jun; 26(6):806-816.
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Late Events Occurring After 5?Years in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group. Pediatr Blood Cancer. 2025 Jan; 72(1):e31421.
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Data mining for second malignancies after CAR-T. Blood. 2024 05 16; 143(20):2023-2024.
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Second primary cancer risks according to race and ethnicity among U.S. breast cancer survivors. Int J Cancer. 2024 Sep 15; 155(6):996-1006.
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Clonal Hematopoiesis and Therapy-Related Myeloid Neoplasms After Autologous Transplant for Hodgkin Lymphoma. J Clin Oncol. 2024 Jul 10; 42(20):2415-2424.
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Germline Genetic Testing and Survival Outcomes Among Children With Rhabdomyosarcoma: A Report From the Children's Oncology Group. JAMA Netw Open. 2024 03 04; 7(3):e244170.
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Serum Tumor Markers and Outcomes in Patients With Appendiceal Adenocarcinoma. JAMA Netw Open. 2024 02 05; 7(2):e240260.
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Risk model-based management for second primary lung cancer among lung cancer survivors through a validated risk prediction model. Cancer. 2024 03 01; 130(5):770-780.
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Margetuximab in HER2-positive metastatic breast cancer. Future Oncol. 2023 May; 19(16):1099-1112.