Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
"Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.
| Descriptor ID |
D000074884
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| MeSH Number(s) |
D08.811.277.656.262.500.126.775 D08.811.277.656.300.200.126.775 D08.811.464.938.750.233
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein".
This graph shows the total number of publications written about "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" by people in this website by year, and whether "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" by people in Profiles.
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Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application. Haematologica. 2024 05 01; 109(5):1348-1358.
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Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma. J Clin Invest. 2023 02 01; 133(3).
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Deletion of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis. Arthritis Rheumatol. 2019 12; 71(12):2005-2015.
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The CBM Complex Underwrites NF-?B Activation to Promote HER2-Associated Tumor Malignancy. Mol Cancer Res. 2016 Jan; 14(1):93-102.
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C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-?B activation. J Biol Chem. 2014 Oct 24; 289(43):30052-62.
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Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity. 2014 May 15; 40(5):692-705.
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The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity. Cell Host Microbe. 2012 Mar 15; 11(3):277-89.
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Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature. 2009 Mar 05; 458(7234):92-6.
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MALT lymphoma involving the kidney: a report of 10 cases and review of the literature. Am J Clin Pathol. 2007 Sep; 128(3):464-73.
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Enhanced survival in perineural invasion of pancreatic cancer: an in vitro approach. Hum Pathol. 2007 Feb; 38(2):299-307.