Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
"Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.
| Descriptor ID |
D000074884
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| MeSH Number(s) |
D08.811.277.656.262.500.126.775 D08.811.277.656.300.200.126.775 D08.811.464.938.750.233
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein".
This graph shows the total number of publications written about "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" by people in this website by year, and whether "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" by people in Profiles.
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Novel Agents in Waldenstr?m Macroglobulinemia. Hematol Oncol Clin North Am. 2023 08; 37(4):751-760.
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Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity. 2014 May 15; 40(5):692-705.
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The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity. Cell Host Microbe. 2012 Mar 15; 11(3):277-89.
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Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature. 2009 Mar 05; 458(7234):92-6.
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Enhanced survival in perineural invasion of pancreatic cancer: an in vitro approach. Hum Pathol. 2007 Feb; 38(2):299-307.
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CIAP2 inhibits anigen receptor signaling by targeting Bcl10 for degredation. Cell Cycle. 2006 Jul; 5(13):1438-42.
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A loss-of-function RNA interference screen for molecular targets in cancer. Nature. 2006 May 04; 441(7089):106-10.
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cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. J Clin Invest. 2006 Jan; 116(1):174-81.
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MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells. Blood. 2005 Apr 01; 105(7):2891-9.
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The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling. Semin Immunol. 2004 Dec; 16(6):429-35.