"Caspase 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
| Descriptor ID |
D053454
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550.920 D08.811.277.656.300.200.126.550.920 D12.644.360.075.405.550.920 D12.776.476.075.405.550.920
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caspase 12".
Below are MeSH descriptors whose meaning is more specific than "Caspase 12".
This graph shows the total number of publications written about "Caspase 12" by people in this website by year, and whether "Caspase 12" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 12" by people in Profiles.
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Conditioned Medium from Mesenchymal Stem Cells Alleviates Endothelial Dysfunction of Vascular Grafts Submitted to Ischemia/Reperfusion Injury in 15-Month-Old Rats. Cells. 2021 05 17; 10(5).
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Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis. PLoS One. 2016; 11(10):e0164115.
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Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes. Cell Death Dis. 2015 Jul 09; 6:e1813.
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The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells. Mol Ther. 2004 Mar; 9(3):355-67.
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The effect of ursodeoxycholic acid on the survivin in thapsigargin-induced apoptosis. Cancer Lett. 2003 Feb 28; 191(1):83-92.
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Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep; 36(3):592-601.