"Micrococcal Nuclease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the endonucleolytic cleavage to 3'-phosphomononucleotide and 3'-phospholigonucleotide end-products. It can cause hydrolysis of double- or single-stranded DNA or RNA. (From Enzyme Nomenclature, 1992) EC 3.1.31.1.
| Descriptor ID |
D008836
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| MeSH Number(s) |
D08.811.277.352.335.350.500 D08.811.277.352.355.325.500 D08.811.277.352.355.350.500 D08.811.277.352.700.350.500
|
| Concept/Terms |
Micrococcal Nuclease- Micrococcal Nuclease
- Nuclease, Micrococcal
- TNase
- Thermostable Nuclease
- Nuclease, Thermostable
- Staphylococcal Nuclease
- Nuclease, Staphylococcal
- Thermonuclease
|
Below are MeSH descriptors whose meaning is more general than "Micrococcal Nuclease".
Below are MeSH descriptors whose meaning is more specific than "Micrococcal Nuclease".
This graph shows the total number of publications written about "Micrococcal Nuclease" by people in this website by year, and whether "Micrococcal Nuclease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Micrococcal Nuclease" by people in Profiles.
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Inhibitors of Streptococcus pneumoniae surface endonuclease EndA discovered by high-throughput screening using a PicoGreen fluorescence assay. J Biomol Screen. 2013 Mar; 18(3):247-57.
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Substrate binding drives large-scale conformational changes in the Hsp90 molecular chaperone. Mol Cell. 2011 Apr 08; 42(1):96-105.
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Nucleosome fragility reveals novel functional states of chromatin and poises genes for activation. Genome Res. 2011 May; 21(5):718-24.
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Probing the conformational state of a truncated staphylococcal nuclease R using time of flight mass spectrometry with limited proteolysis. Eur J Biochem. 2001 Aug; 268(15):4227-32.
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Evidence that partial unwrapping of DNA from nucleosomes facilitates the binding of heat shock factor following DNA replication in yeast. J Biol Chem. 1998 Aug 07; 273(32):20463-72.
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Neither HMG-14a nor HMG-17 gene function is required for growth of chicken DT40 cells or maintenance of DNaseI-hypersensitive sites. Nucleic Acids Res. 1997 Jan 15; 25(2):283-8.
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The importance of anchorage in determining a strained protein loop conformation. Protein Sci. 1994 Apr; 3(4):549-56.
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Yeast alpha 2 repressor positions nucleosomes in TRP1/ARS1 chromatin. Mol Cell Biol. 1990 May; 10(5):2247-60.
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Chromatin structure of the ovalbumin gene family in the chicken oviduct. Biochemistry. 1983 Jan 04; 22(1):21-30.
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Altered gel electrophoretic mobility of bleomycin-mediated release of nucleosomal DNA. Cancer Res. 1981 Jun; 41(6):2433-8.