"Ribonuclease H" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms as well as RETROVIRUSES.
| Descriptor ID |
D016914
|
| MeSH Number(s) |
D08.811.277.352.355.350.700 D08.811.277.352.700.350.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ribonuclease H".
Below are MeSH descriptors whose meaning is more specific than "Ribonuclease H".
This graph shows the total number of publications written about "Ribonuclease H" by people in this website by year, and whether "Ribonuclease H" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ribonuclease H" by people in Profiles.
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Systemic complications of Aicardi Gouti?res syndrome using real-world data. Mol Genet Metab. 2024 Sep-Oct; 143(1-2):108578.
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Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Mol Cancer Ther. 2024 Jul 02; 23(7):1057-1065.
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RNase H genes cause distinct impacts on RNA:DNA hybrid formation and mutagenesis genome wide. Sci Adv. 2023 07 28; 9(30):eadi5945.
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A non-coding RNASEH1 gene variant associates with type 1 diabetes and interacts with HLA tagSNPs in families from Colombia. Pediatr Diabetes. 2020 11; 21(7):1183-1192.
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Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition. Oncogene. 2019 04; 38(14):2451-2463.
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Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Nat Commun. 2016 10 05; 7:13049.
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Adapting capillary gel electrophoresis as a sensitive, high-throughput method to accelerate characterization of nucleic acid metabolic enzymes. Nucleic Acids Res. 2016 Jan 29; 44(2):e15.
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Assessment of interferon-related biomarkers in Aicardi-Gouti?res syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study. Lancet Neurol. 2013 Dec; 12(12):1159-69.
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RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1. Proc Natl Acad Sci U S A. 2012 Mar 13; 109(11):4221-6.
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R loops stimulate genetic instability of CTG.CAG repeats. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):692-7.