Deoxyribonuclease IV (Phage T4-Induced)
"Deoxyribonuclease IV (Phage T4-Induced)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.
| Descriptor ID |
D043223
|
| MeSH Number(s) |
D08.811.277.352.335.350.275
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Deoxyribonuclease IV (Phage T4-Induced)".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonuclease IV (Phage T4-Induced)".
This graph shows the total number of publications written about "Deoxyribonuclease IV (Phage T4-Induced)" by people in this website by year, and whether "Deoxyribonuclease IV (Phage T4-Induced)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxyribonuclease IV (Phage T4-Induced)" by people in Profiles.
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The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once. DNA Repair (Amst). 2014 Jul; 19:95-107.
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Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. J Biol Chem. 2013 Mar 22; 288(12):8445-8455.
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DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nat Struct Mol Biol. 2008 May; 15(5):515-22.
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Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV. Proc Natl Acad Sci U S A. 2007 Jan 30; 104(5):1465-70.
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Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer. Mol Carcinog. 2001 Aug; 31(4):214-23.
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A thermostable endonuclease III homolog from the archaeon Pyrobaculum aerophilum. Nucleic Acids Res. 2001 Feb 01; 29(3):604-13.
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DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. Prog Nucleic Acid Res Mol Biol. 2001; 68:315-47.
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Lessons learned from structural results on uracil-DNA glycosylase. Mutat Res. 2000 Aug 30; 460(3-4):183-99.
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Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means. Mutat Res. 2000 Aug 30; 460(3-4):211-29.
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The food of sweet and bitter fancy. Nat Struct Biol. 2000 Jan; 7(1):17-8.