"Polymyxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
| Descriptor ID |
D011113
|
| MeSH Number(s) |
D04.345.566.780 D10.477.750 D12.644.050.600 D12.644.641.780 D12.776.543.695.054.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Polymyxins".
Below are MeSH descriptors whose meaning is more specific than "Polymyxins".
This graph shows the total number of publications written about "Polymyxins" by people in this website by year, and whether "Polymyxins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Polymyxins" by people in Profiles.
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Zileuton ameliorates aminoglycoside and polymyxin-associated acute kidney injury in an animal model. J Antimicrob Chemother. 2023 10 03; 78(10):2435-2441.
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Structural biology of MCR-1-mediated resistance to polymyxin antibiotics. Curr Opin Struct Biol. 2023 10; 82:102647.
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Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1. mBio. 2021 12 21; 12(6):e0277621.
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In-Vitro Assessment Of The Therapeutic Potential Of Polymyxins And Tigecycline Against Multidrugresistant Acinetobacter Isolates From Infected Wounds. J Ayub Med Coll Abbottabad. 2020 Oct-Dec; 32(4):459-464.
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Outcomes of Lung Transplantation for Cystic Fibrosis in the Setting of Extensively Drug-Resistant Organisms. Prog Transplant. 2019 09; 29(3):220-224.
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Toxicity in Patients. Adv Exp Med Biol. 2019; 1145:289-304.
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Analytical and functional determination of polymyxin B protein binding in serum. Antimicrob Agents Chemother. 2015 Nov; 59(11):7121-3.
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In vitro assessment and multicenter cohort study of comparative nephrotoxicity rates associated with colistimethate versus polymyxin B therapy. Antimicrob Agents Chemother. 2014 May; 58(5):2740-6.
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Reply to Nation et al. Clin Infect Dis. 2013 Dec; 57(11):1657-8.
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Polymyxins: wisdom does not always come with age. Clin Infect Dis. 2013 Sep; 57(6):877-83.