"Defensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of antimicrobial peptides that have been identified in humans, animals, and plants. They are thought to play a role in host defenses against infections, inflammation, wound repair, and acquired immunity.
Descriptor ID |
D023082
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MeSH Number(s) |
D12.644.050.200 D12.776.543.695.054.200
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Defensins".
Below are MeSH descriptors whose meaning is more specific than "Defensins".
This graph shows the total number of publications written about "Defensins" by people in this website by year, and whether "Defensins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 0 | 1 | 1 |
1998 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Defensins" by people in Profiles.
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CD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice. J Control Release. 2022 09; 349:796-811.
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Differential Expression of Putative Ornithodoros turicata Defensins Mediated by Tick Feeding. Front Cell Infect Microbiol. 2020; 10:152.
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Repurposing a drug targeting peptide for targeting antimicrobial peptides against Staphylococcus. Biotechnol Lett. 2020 Feb; 42(2):287-294.
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Comparative genomic study of arachnid immune systems indicates loss of beta-1,3-glucanase-related proteins and the?immune deficiency pathway. J Evol Biol. 2016 Feb; 29(2):277-91.
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Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye. Cornea. 2008 Aug; 27(7):811-7.
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Macrophage migration inhibitory factor in patients with preterm parturition and microbial invasion of the amniotic cavity. J Matern Fetal Neonatal Med. 2005 Dec; 18(6):405-16.
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Defensins and cathelicidins: neutrophil peptides with roles in inflammation, hyperlipidemia and atherosclerosis. J Cell Mol Med. 2005 Jan-Mar; 9(1):3-10.
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Theta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. J Virol. 2004 May; 78(10):5147-56.
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Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human. Endocrinology. 2001 Oct; 142(10):4529-39.
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Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract. Am J Pathol. 1998 May; 152(5):1247-58.