"alpha-Defensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.
| Descriptor ID |
D023084
|
| MeSH Number(s) |
D12.644.050.200.050 D12.776.543.695.054.200.050
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "alpha-Defensins".
Below are MeSH descriptors whose meaning is more specific than "alpha-Defensins".
This graph shows the total number of publications written about "alpha-Defensins" by people in this website by year, and whether "alpha-Defensins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2006 | 2 | 0 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 1 | 2 |
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "alpha-Defensins" by people in Profiles.
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Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal Immunol. 2019 03; 12(2):491-502.
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Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cell Mol Gastroenterol Hepatol. 2019; 7(3):533-554.
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Decellularized colorectal cancer matrix as bioactive microenvironment for in vitro 3D cancer research. J Cell Physiol. 2018 08; 233(8):5937-5948.
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Delineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibition. PLoS Pathog. 2014 Sep; 10(9):e1004360.
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Activation of neutrophils by the two-component leukotoxin LukE/D from Staphylococcus aureus: proteomic analysis of the secretions. J Proteome Res. 2013 Aug 02; 12(8):3667-78.
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Macaque paneth cells express lymphoid chemokine CXCL13 and other antimicrobial peptides not previously described as expressed in intestinal crypts. Clin Vaccine Immunol. 2013 Aug; 20(8):1320-8.
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An altered immune response, but not individual cationic antimicrobial peptides, is associated with the oral attenuation of Ara4N-deficient Salmonella enterica serovar Typhimurium in mice. PLoS One. 2012; 7(11):e49588.
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Detection of bladder cancer using proteomic profiling of urine sediments. PLoS One. 2012; 7(8):e42452.
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Overexpression of alpha-defensin is associated with bladder cancer invasiveness. Urol Oncol. 2006 Mar-Apr; 24(2):97-108.
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Neutrophil antimicrobial peptide alpha-defensin causes endothelial dysfunction in porcine coronary arteries. J Vasc Surg. 2006 Feb; 43(2):357-63.