"Colistin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
| Descriptor ID |
D003091
|
| MeSH Number(s) |
D04.345.566.780.110 D10.477.750.110 D12.644.050.600.110 D12.644.641.780.110 D12.776.543.695.054.600.110
|
| Concept/Terms |
Colistin- Colistin
- Colisticin
- Polymyxin E
- Colimycin
|
Below are MeSH descriptors whose meaning is more general than "Colistin".
Below are MeSH descriptors whose meaning is more specific than "Colistin".
This graph shows the total number of publications written about "Colistin" by people in this website by year, and whether "Colistin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 4 | 1 | 5 |
| 2016 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 2 | 4 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Colistin" by people in Profiles.
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Structural biology of MCR-1-mediated resistance to polymyxin antibiotics. Curr Opin Struct Biol. 2023 10; 82:102647.
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Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli. Nat Commun. 2022 06 09; 13(1):3189.
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Rescuing humanity by antimicrobial peptides against colistin-resistant bacteria. Appl Microbiol Biotechnol. 2022 Jun; 106(11):3879-3893.
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MgrB-Dependent Colistin Resistance in Klebsiella pneumoniae Is Associated with an Increase in Host-to-Host Transmission. mBio. 2022 04 26; 13(2):e0359521.
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Antibiotic Resistance Pattern Of Acinetobacter Baumannii Isolated From Bacteremia Patients In Pakistan. J Ayub Med Coll Abbottabad. 2022 Jan-Mar; 34(1):95-100.
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Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1. mBio. 2021 12 21; 12(6):e0277621.
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In vitro activity of colistin against multidrug-resistant Acinetobacter baumannii isolates harboring blaOXA-23-like and blaOXA-24-like genes: A multicenter based study. Acta Microbiol Immunol Hung. 2020 Mar 09; 67(3):182-186.
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International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti-infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP). Pharmacotherapy. 2019 01; 39(1):10-39.
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CTX-M-55-, MCR-1-, and FosA-Producing Multidrug-Resistant Escherichia coli Infection in a Child in France. Antimicrob Agents Chemother. 2018 04; 62(4).
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High Rates of Human Fecal Carriage of mcr-1-Positive Multidrug-Resistant Enterobacteriaceae Emerge in China in Association With Successful Plasmid Families. Clin Infect Dis. 2018 02 10; 66(5):676-685.